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N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide

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Identification
Molecular formula
C16H18N4O2
CAS number
.
IUPAC name
N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide
State
State

Under room temperature conditions, this compound exists as a solid.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.20
Boiling point (Celsius)
586.30
Boiling point (Kelvin)
859.50
General information
Molecular weight
268.34g/mol
Molar mass
268.3030g/mol
Density
1.2950g/cm3
Appearence

The compound is a crystalline solid, often appearing as a fine powder or small crystals. It is generally white to off-white in color.

Comment on solubility

Solubility of N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide

N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide, with the chemical formula C16H18N4O2, presents interesting considerations regarding its solubility. The solubility of a compound is influenced by various factors, and for this compound, several points are essential to note:

  • Polarity: The presence of the carbonyl and hydrazine functional groups may introduce polar characteristics, potentially enhancing solubility in polar solvents.
  • Hydrogen Bonding: This compound can engage in hydrogen bonding due to the active hydrogen atoms in the hydrazino group, which may promote solubility in protic solvents like water.
  • Solvent Compatibility: It is anticipated that N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide may be soluble in dimethyl sulfoxide (DMSO) and ethanol, while its solubility in non-polar solvents could be limited.
  • Temperature Influence: Like many organic compounds, increased temperature may enhance solubility, thus it is advisable to consider solubility studies at elevated temperatures.

In summary, one might expect that N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide exhibits variable solubility depending on the solvent environment and temperature. It illustrates the intricate nature of solubility in organic compounds, where structural features significantly guide interactions with different solvents.

Interesting facts

Interesting Facts about N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide

N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide is a fascinating compound with intriguing properties and potential applications in various fields. Here are some noteworthy aspects:

  • Structural Complexity: This compound features a multi-functional structure, incorporating both benzyl and pyridine moieties, which contributes to its chemical behavior and reactivity.
  • Biological Significance: Compounds similar to N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide have been explored in medicinal chemistry for their potential antifungal and antiviral activities, making them important in pharmaceutical research.
  • Versatile Reactions: The presence of the hydrazino group provides opportunities for various coupling reactions, making it a building block for synthesizing more complex compounds.
  • Research Relevance: Due to its unique structure, this compound serves as a subject of interest for studies related to drug design and development. Its interactions with biological targets are a pivotal area of investigation.
  • Hybrids and Conjugates: Scientists are exploring the synthesis of hybrid compounds that combine N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide with other pharmacophores to enhance therapeutic efficacy.

In summary, N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide showcases the intricate interplay of organic chemistry and pharmacology. It acts as a valuable template for further research and development, illustrating the continual evolution of chemical discovery and innovation. As noted by chemists, "The beauty of chemistry lies not just in its complexity, but also in its potential to solve real-world problems."

Synonyms
Nialamide
51-12-7
Niamid
Nialamid
Niaquitil
Niamidal
Niazin
Psicodisten
Novazid
Nuredal
Nyazin
Mygal
Delmoneurina
Isalizina
Espril
Surgex
BEIH
Nialamida
Delmoneurinaesprilisalizina
Nialamidum [INN-Latin]
Nialamida [INN-Spanish]
Nialamidum
N-Benzyl-beta-(isonicotinylhydrazino)propionamide
N-(2-(Benzylcarbamyl)ethylamino)isonicotinamide
CCRIS 3512
2-(2-(Benzylcarbamyl)ethyl)hydrazide isonicotinic acid
NSC 124514
2-(2-(Benzylcarbamoyl)ethyl)hydrazide isonicotinic acid
P 1133
N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazinyl]propanamide
N-Benzyl-beta-(isonicotinoylhydrazine)propionamide
Nialamide [INN:BAN:NF]
EINECS 200-079-3
1-(2-(Benzylcarbamoyl)ethyl)-2-isonicotinoylhydrazine
Nialamide (INN)
Isonicotinic acid 2-((2-benzylcarbamoyl)ethyl)hydrazide
Isonicotinic acid, 2-(2-(benzylcarbamoyl)ethyl)hydrazide
N-Isonicotinoyl-N'(beta-N-benzylcarboxamidoethyl)hydrazine
NSC-124514
Niamid (TN)
BRN 0492941
T2Q0RYM725
DTXSID1023362
HSDB 7698
NIALAMIDE [INN]
NIALAMIDE [MI]
NIALAMIDE [HSDB]
NSC124514
NIALAMIDE [MART.]
NIALAMIDE [WHO-DD]
4-Pyridinecarboxylic acid, 2-(3-oxo-3-((phenylmethyl)amino)propyl)hydrazide
4-Pyridinecarboxylic acid, 2-[3-oxo-3-[(phenylmethyl)amino]propyl]hydrazide
MLS000069474
DTXCID503362
N(sup1)-beta-Benzylcarbamoylethyl-N(sup2)-isonicotinoylhydrazine
N(sup 1)-beta-Benzylcarbamoylethyl-N(sup 2)-isonicotinoylhydrazine
5-22-02-00251 (Beilstein Handbook Reference)
4-Pyridinecarboxylic acid 2-(3-oxo-3-((phenylmethyl)amino)propyl)hydrazide
1-[2-(Benzylcarbamoyl)ethyl]-2-isonicotinoylhydrazine
CAS-51-12-7
Isonicotinic acid, 2-[2-(benzylcarbamoyl)ethyl]hydrazide
NCGC00015726-06
SMR000059131
Nialamidum (INN-Latin)
Nialamida (INN-Spanish)
NIALAMIDE (MART.)
N-Benzyl-.beta.-(isonicotinylhydrazino)propionamide
N-Benzyl-.beta.-(isonicotinoylhydrazine)propionamide
N-benzyl-3-[(pyridin-4-yl)formohydrazido]propanamide
2-[2-(Benzylcarbamoyl)ethyl]hydrazide isonicotinic acid
N-Isonicotinoyl-N'-(.beta.-N-benzylcarboxamidoethyl)hydrazine
Nyezin
4-Pyridinecarboxylic acid 2-[3-oxo-3-[(phenylmethyl)amino]propyl]hydrazide
N-Isonicotinyl hydrazide
SR-01000000028
Lopac-N-1392
N-Benzyl-3-(2-isonicotinoylhydrazino)propanamide
UNII-T2Q0RYM725
Nialamide, 95%
Opera_ID_1336
Prestwick0_001099
Prestwick1_001099
Prestwick2_001099
Prestwick3_001099
CBChromo1_000220
Nucleic Acid Electrophoresis
Lopac0_000865
SCHEMBL49430
BSPBio_001178
MLS001076132
MLS001424258
SPBio_003059
WLN: T6NJ DVMM2VM1R
BPBio1_001296
CHEMBL1256841
Isonicitinic acid 2-[(2-benzylcarbamoyl)ethyl]hydrazide
Isonicotinic acid, 2-[2-(benzylcarbamoylethyl]hydrazide
CHEBI:94510
N06AF02
BDBM163693
HMS1571K20
HMS2052O21
HMS2089M13
HMS2093L10
HMS2098K20
HMS2233A06
HMS3262N11
HMS3372J15
HMS3394O21
HMS3715K20
Pharmakon1600-01505986
HY-B1199
Tox21_110208
Tox21_500865
NSC759298
AKOS003390166
Tox21_110208_1
CCG-101150
CS-4827
DB04820
LP00865
NC00400
NSC-759298
SDCCGSBI-0050840.P003
NCGC00015726-01
NCGC00015726-02
NCGC00015726-03
NCGC00015726-04
NCGC00015726-05
NCGC00015726-07
NCGC00015726-08
NCGC00015726-09
NCGC00015726-11
NCGC00015726-16
NCGC00022832-03
NCGC00022832-04
NCGC00261550-01
MS-24288
SBI-0050840.P002
DB-051905
AB00384282
EU-0100865
NS00003489
SW197230-4
D07337
F85257
N 1392
AB00384282-14
AB00384282_15
AB00384282_16
EN300-12579134
N-benzyl-3-(2-isonicotinoylhydrazinyl)propanamide
N-benzyl-3-(pyridin-4-ylformohydrazido)propanamide
N-Benzyl-3-(2-isonicotinoylhydrazino)propanamide #
Q2359711
SR-01000000028-2
SR-01000000028-5
SR-01000000028-7
SR-01000000028-8
BRD-K12102668-001-04-0
BRD-K12102668-001-24-8
BRD-K12102668-001-25-5
N1-.beta.-Benzylcarbamoylethyl-N2-isonicotinoylhydrazine
N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide
3-[[oxo(pyridin-4-yl)methyl]hydrazo]-N-(phenylmethyl)propanamide
Hydrazine, N-isonicotinoyl-N'-[beta-(N-benzylcarboxamido)ethyl]-
n(sup1)-.beta.-Benzylcarbamoylethyl-n(sup2)isonicotinoylhydrazine
N-(phenylmethyl)-3-[2-(pyridin-4-ylcarbonyl)hydrazino]propanamide
N-Benzyl-3-[N'-(1-pyridin-4-yl-methanoyl)-hydrazino]-propionamide
4-Pyridinecarboxylic acid, 2-(3-oxo-3-((phenylmethyl)amino)propyl)hydrazide (9CI)
200-079-3