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N-benzyl-4-sulfamoyl-benzamide

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Identification
Molecular formula
C14H14N2O3S
CAS number
n/a
IUPAC name
N-benzyl-4-sulfamoyl-benzamide
State
State

At room temperature, N-benzyl-4-sulfamoyl-benzamide is in a solid state. It is stable and generally does not degrade under normal atmospheric conditions.

Melting point (Celsius)
245.00
Melting point (Kelvin)
518.00
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.00
General information
Molecular weight
290.34g/mol
Molar mass
290.3400g/mol
Density
1.4200g/cm3
Appearence

N-benzyl-4-sulfamoyl-benzamide is typically a white to off-white crystalline powder. It is odorless and has a distinct crystalline texture.

Comment on solubility

Solubility of N-benzyl-4-sulfamoyl-benzamide

N-benzyl-4-sulfamoyl-benzamide, with the chemical formula C14H14N2O3S, is an intriguing compound with specific solubility characteristics. Understanding its solubility helps in determining practical applications and interactions with various solvents.

Generally, the solubility of N-benzyl-4-sulfamoyl-benzamide can be summarized as follows:

  • Solvent Interactions: This compound exhibits a tendency to dissolve in polar solvents due to the presence of the sulfonamide functional group. Polar solvents such as water and ethanol may facilitate its dissolving process.
  • Non-Polar Solvent Behavior: Conversely, this compound shows limited solubility in non-polar solvents. Therefore, it might not dissolve well in solvents like hexane or benzene.
  • pH Sensitivity: The solubility can be affected by the pH of the solution, which can lead to variations in ionization; hence shifting the solubility profile in different environments.

In summary, the solubility of N-benzyl-4-sulfamoyl-benzamide is influenced by its molecular structure and functional groups, emphasizing the importance of solvent choice in its application. As often stated, "like dissolves like," and this compound fits well within that principle, showcasing significant solubility in polar media while demonstrating restrictions in non-polar contexts.

Interesting facts

Interesting Facts about N-benzyl-4-sulfamoyl-benzamide

N-benzyl-4-sulfamoyl-benzamide is a fascinating compound that belongs to the class of sulfonamide drugs, renowned for their antibacterial properties. Here are some engaging insights about this compound:

  • Medicinal Applications: Compounds like N-benzyl-4-sulfamoyl-benzamide have sparked interest in pharmaceutical research due to their potential in treating various bacterial infections. Sulfanilamide, a well-known member of this class, laid the groundwork for the development of antibiotics.
  • Biomedical Significance: Researchers are continuously exploring derivatives of sulfonamide compounds to enhance their efficacy and reduce side effects. The presence of the sulfonamide group in this compound contributes significantly to its biological activity.
  • Structure-Activity Relationship: The unique structure of N-benzyl-4-sulfamoyl-benzamide allows for various substitutions, which can lead to enhanced pharmacological profile, making it a subject of active investigation in medicinal chemistry.
  • Synthesis Techniques: The synthesis of compounds like this often involves innovative chemical reactions, showcasing the creativity and problem-solving skills of chemists in designing effective drug molecules.
  • Research Opportunities: For aspiring chemists and seasoned researchers alike, the study of sulfonamide derivatives opens exciting avenues for discovery, from optimizing the molecular design to understanding their mechanisms of action.

In summary, N-benzyl-4-sulfamoyl-benzamide represents not only a crucial player in medicinal chemistry but also offers plentiful opportunities for research and development aimed at tackling infectious diseases. As John C. Martin, a renowned chemist, once said, "If you think research is expensive, try disease!" This underscores the importance of exploring compounds like N-benzyl-4-sulfamoyl-benzamide in the quest for effective treatments.

Synonyms
n-benzyl-4-sulfamoyl-benzamide
N-benzyl-4-sulfamoylbenzamide
107619-27-2
6LQK8L3YE9
CHEMBL302715
CHEBI:41231
DTXSID80274429
4-(aminosulfonyl)-N-benzylbenzamide
N-benzyl-4-(aminosulfonyl)benzamide
4-(benzylcarbamoyl)benzenesulfonamide
1g4o
Benzamide, 4-(aminosulfonyl)-N-(phenylmethyl)-
SCHEMBL678390
BDBM12013
n-(4-sulfamylbenzoyl)benzylamine
DTXCID50225908
Benzamide, N-benzyl-p-sulfamoyl-
HMS3604F04
AKOS001408419
DB01748
N-(Phenylmethyl)-4-sulfamoyl-benzamide
4-(Aminosulfonyl)-N-(phenylmethyl)benzamide
NS00068287
4-(AMINOSULFONYL)-N-PHENYLMETHYLBENZAMIDE
EN300-26181507
Q27092910
Z31477806