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N'-benzyl-5-methylisoxazole-3-carbohydrazide

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Identification
Molecular formula
C12H13N3O2
CAS number
3270-98-2
IUPAC name
N'-benzyl-5-methyl-isoxazole-3-carbohydrazide
State
State

At room temperature, N'-benzyl-5-methyl-isoxazole-3-carbohydrazide is typically found as a solid. Its crystalline structure and relatively high melting point support its solid state under standard conditions.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
245.26g/mol
Molar mass
245.2630g/mol
Density
1.2000g/cm3
Appearence

N'-benzyl-5-methyl-isoxazole-3-carbohydrazide typically appears as a white or off-white crystalline solid. The compound's structure contributes to its stability and distinct appearance, with crystalline forms that may also appear slightly powdery depending on the sample's purity and method of crystallization.

Comment on solubility

Solubility of N'-benzyl-5-methyl-isoxazole-3-carbohydrazide

N'-benzyl-5-methyl-isoxazole-3-carbohydrazide (C12H13N3O2) demonstrates some notable characteristics regarding its solubility:

  • Polar Characteristics: The compound's structure includes polar functional groups, which can enhance solubility in polar solvents such as water or ethanol.
  • Non-Polar Characteristics: The presence of the benzyl group may also impart some non-polar characteristics, suggesting that N'-benzyl-5-methyl-isoxazole-3-carbohydrazide could also be soluble in organic solvents like chloroform or dichloromethane.
  • Solubility Variability: It is important to note that the solubility of this compound can vary significantly with temperature and pH, making experimentation crucial for determining precise solubility limits.

Overall, the compound's solubility profile can be summarized as follows:

  • Potential for moderate solubility in polar solvents.
  • Increased solubility in non-polar organic solvents.
  • Temperature and solvent choice greatly influence solubility behavior.

In conclusion, understanding the solubility of N'-benzyl-5-methyl-isoxazole-3-carbohydrazide provides essential insights for its applications and handling in various chemical and pharmaceutical settings.

Interesting facts

Interesting Facts about N'-benzyl-5-methyl-isoxazole-3-carbohydrazide

N'-benzyl-5-methyl-isoxazole-3-carbohydrazide is a fascinating compound with intriguing properties and applications in various fields. Here are some notable facts about this compound:

  • Structural Uniqueness: This compound features an isoxazole ring, which is known for its presence in numerous bioactive molecules. The isoxazole structure contributes to its stability and chemical reactivity.
  • Biological Activity: Compounds containing isoxazole moieties often exhibit significant biological properties, including antimicrobial, anti-inflammatory, and anticancer activities. Research is ongoing to explore the potential pharmacological applications of N'-benzyl-5-methyl-isoxazole-3-carbohydrazide.
  • Versatile Synthetic Routes: The synthesis of this compound can be approached via various methods, including hydrazine and carboxylic acid derivatives. Understanding these synthesis pathways is essential for its production in the lab.
  • Research Opportunities: As scientists continue to investigate the properties of this compound, it opens doors for developing new derivatives with enhanced potency or reduced toxicity, especially in therapeutic contexts.
  • Intermolecular Interactions: The presence of polar functional groups in this compound suggests the potential for strong intermolecular interactions, including hydrogen bonding, that could influence its solubility and reactivity with other molecules.

Overall, N'-benzyl-5-methyl-isoxazole-3-carbohydrazide is a compound that exemplifies the fascinating intersection of organic chemistry and medicinal research. As scientists delve deeper into its properties, we can anticipate new discoveries that may contribute to advancements in pharmaceuticals and materials science. As the well-known chemist Marie Curie once said, “Nothing in life is to be feared, it is only to be understood.” With compounds such as this, understanding could lead to significant breakthroughs!

Synonyms
isocarboxazid
59-63-2
Isocarboxazide
Marplan
Enerzer
Isocarbonazid
Benazide
N'-Benzyl-5-methylisoxazole-3-carbohydrazide
Isocarbossazide
Isocarboxyzid
Marplon
Isocarboxazida
N'-benzyl-5-methyl-1,2-oxazole-3-carbohydrazide
Isocarbossazide [DCIT]
Isocarboxazidum
Maraplan
Ro 5-0831
Isocarboxazide [INN-French]
Isocarboxazidum [INN-Latin]
Isocarboxazida [INN-Spanish]
Ro 5-0831/1
BMIH
5-Methyl-3-isoxazolecarboxylic acid 2-benzylhydrazide
3-Isoxazolecarboxylic acid, 5-methyl-, 2-(phenylmethyl)hydrazide
N'-Benzyl N-methyl-5-isoxazolecarboxylhydrazide-3
CCRIS 9178
NSC 169893
EINECS 200-438-4
NSC-169893
BRN 0201295
Isocarboxazid (INN)
DTXSID4023171
1-Benzyl-2-(5-methyl-3-isoxazolyl-carbonyl)hydrazine
UNII-34237V843T
3-Isoxazolecarboxylic acid, 5-methyl-, 2-benzylhydrazide
1-Benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine
59-63-2 (free base)
MLS003106729
RO-5-0831
DTXCID003171
Isocarboxazid [USP:INN:BAN]
34237V843T
4-27-00-03999 (Beilstein Handbook Reference)
NSC169893
CAS-59-63-2
NCGC00016267-01
ISOCARBOXAZID [INN]
Isocarboxazide (INN-French)
Isocarboxazidum (INN-Latin)
Isocarboxazida (INN-Spanish)
ISOCARBOXAZID (MART.)
ISOCARBOXAZID [MART.]
ISOCARBOXAZID (USP-RS)
ISOCARBOXAZID [USP-RS]
Isocarboxazid (USP:INN:BAN)
SMR001233334
Marplan (TN)
Isocarboxazid (1.0 mg/mL in Acetonitrile)
SR-01000841192
Isocarboxacid
Isocarboxazid (ICD)
Isocarboxazid (Standard)
Prestwick0_000795
Prestwick1_000795
Prestwick2_000795
Prestwick3_000795
ISOCARBOXAZID [MI]
SCHEMBL49562
BSPBio_000930
MLS002154005
5-methyl-N'-(phenylmethyl)isoxazole-3-carbohydrazide
SPBio_002869
ISOCARBOXAZID [WHO-DD]
BPBio1_001024
GTPL7204
CHEMBL1201168
WLN: T5NOJ C1 EVMM1R
CHEBI:93635
ISOCARBOXAZID (200 MG)
N06AF01
BDBM163692
GLXC-02865
HMS1570O12
HMS2097O12
HMS2230E11
HMS3369G18
HMS3714O12
HMS3887K05
ISOCARBOXAZID [ORANGE BOOK]
Tox21_110336
HY-13929R
AKOS016003091
CCG-220795
DB01247
NCGC00016267-02
NCGC00016267-03
NCGC00016267-06
AC-24841
DA-64526
HY-13929
MS-23317
AB00513923
CS-0008613
NS00007049
3-Isoxazolecarboxylic acid, 2-benzylhydrazide
N?-Benzyl-5-methylisoxazole-3-carbohydrazide
D02580
G12701
N'-Benzyl-5-methyl-3-isoxazolecarbohydrazide #
EN300-12578055
Q409595
SR-01000841192-2
SR-01000841192-3
3-Isoxazolecarboxylic acid, 2-(phenylmethyl)hydrazide
5-methyl-N'-(phenylmethyl)-3-isoxazolecarbohydrazide
BRD-K93332168-001-03-2
BRD-K93332168-001-10-7
BRD-K93332168-001-11-5
Z2044793215
Isocarboxazid 5-methyl-3-isoxazole-carboxylic acid 2-benzylhydrazide, AldrichCPR
200-438-4