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N-Benzyl-N-methylprop-2-yn-1-amine hydrochloride

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Identification
Molecular formula
C11H14ClN
CAS number
24806-78-6
IUPAC name
N-benzyl-N-methyl-prop-2-yn-1-amine;hydrochloride
State
State
At room temperature, N-Benzyl-N-methylprop-2-yn-1-amine hydrochloride is typically found in a solid state, specifically as a crystalline powder.
Melting point (Celsius)
191.00
Melting point (Kelvin)
464.15
Boiling point (Celsius)
270.00
Boiling point (Kelvin)
543.15
General information
Molecular weight
221.72g/mol
Molar mass
221.7200g/mol
Density
1.0605g/cm3
Appearence

N-Benzyl-N-methylprop-2-yn-1-amine hydrochloride typically appears as a solid crystalline powder. The color of the powder can range from white to off-white, depending on the purity and specific conditions of preparation.

Comment on solubility

Solubility of N-benzyl-N-methyl-prop-2-yn-1-amine; hydrocholoride

N-benzyl-N-methyl-prop-2-yn-1-amine; hydrochloride is classified as a quaternary ammonium compound. Its solubility can be affected by several factors:

  • Polarity: The hydrochloride salt form typically increases the polarity of the compound, enhancing its solubility in polar solvents such as water.
  • Temperature: Solubility can often increase with temperature, making it more soluble at elevated temperatures.
  • pH Level: The solubility may vary with changes in pH, as it is a salt, thus being more soluble in acidic conditions.

In practice, it is generally observed that quaternary ammonium salts, including this compound, exhibit good solubility in:

  • Water
  • Alcohols
  • Aqueous buffers

For researchers and practitioners working with this compound, it is crucial to ensure that the solubility conditions are met for effective applications. Overall, the solubility characteristics of N-benzyl-N-methyl-prop-2-yn-1-amine; hydrochloride highlight the importance of understanding both the chemical structure and its interactions with solvents.

Interesting facts

Interesting Facts about N-benzyl-N-methyl-prop-2-yn-1-amine Hydrochloride

N-benzyl-N-methyl-prop-2-yn-1-amine hydrochloride, often referred to simply as a type of substituted amine, belongs to a class of compounds that are widely studied for their potential applications in medicinal chemistry. Here are some captivating insights about this compound:

  • Structure and Functionality: The structure of this compound features a triple bond (alkyne) and two amine groups, which grants it unique reactivity patterns compared to simple amines. This architecture can facilitate interactions with biological receptors, thus enhancing its profiles in pharmacological activities.
  • Biological Significance: Compounds similar to N-benzyl-N-methyl-prop-2-yn-1-amine hydrochloride have been examined for their potential applications in treating various neurological disorders. Researchers are particularly interested in their ability to cross the blood-brain barrier, which is crucial for effective drug delivery to the central nervous system.
  • Synthetic Pathways: The synthesis of this compound can involve multiple organic reactions, including alkylation and coupling reactions. Understanding these pathways allows chemists to efficiently produce this compound in the lab for further study or pharmaceutical development.
  • Research and Development: Currently, there is significant interest in modifying the benzyl and methyl groups of this compound to enhance its selectivity and potency. As a result, multiple derivatives are being synthesized and tested in various biological assays.
  • Applications in Materials Science: Beyond medicinal chemistry, the unique properties of N-benzyl-N-methyl-prop-2-yn-1-amine hydrochloride allow it to be explored in materials science, particularly as a precursor for polymers and other functional materials.

In conclusion, N-benzyl-N-methyl-prop-2-yn-1-amine hydrochloride exemplifies the intersection of organic synthesis and biological applications. Its versatility and multifaceted properties underscore the importance of compounds like these in advancing both scientific research and applied technologies. As one researcher eloquently put it, "The beauty of chemistry lies in its ability to transform simple building blocks into complex, functional structures."

Synonyms
Pargyline hydrochloride
306-07-0
Pargyline HCl
Eutonyl
N-Methyl-N-propargylbenzylamine hydrochloride
Eutonyl-ten
Pargyline chloride
N-Methyl-N-2-propynylbenzylamine hydrochloride
N-benzyl-N-methylprop-2-yn-1-amine hydrochloride
USAF A-19120
Benzylmethylpropynylamine hydrochloride
Methylbenzylpropynylamine hydrochloride
Benzenemethanamine, N-methyl-N-2-propynyl-, hydrochloride
Pargyline (hydrochloride)
Pargyline, HCl
UNII-W70V6I2OMY
EINECS 206-175-1
W70V6I2OMY
MFCD00012492
MO-911
NSC 43798
NSC-43798
N-Benzyl-N-methyl-2-propynylamine hydrochloride
Pargyline hydrochloride [USAN]
DTXSID1044647
AI3-62178
N-Methyl-N-propargylbenzylamine HCl
A-19120
2-Propynylamine, N-benzyl-N-methyl-, hydrochloride
Benzenemethanamine, N-methyl-N-2-propyn-1-yl-, hydrochloride (1:1)
MLS000028460
BENZYLAMINE, N-METHYL-N-2-PROPYNYL-, HYDROCHLORIDE
DTXCID9024647
N-Methyl-N-(2-propynyl)benzylamine hydrochloride
N-benzyl-N-methylprop-2-yn-1-amine;hydrochloride
NSC43798
Pargyline hydrochloride [USAN:USP]
SMR000058367
EUTRON COMPONENT PARGYLINE HYDROCHLORIDE
Pargyline hydrochloride (USAN)
Pargyline hydrochloride (USAN:USP)
PARGYLINE HYDROCHLORIDE (MART.)
PARGYLINE HYDROCHLORIDE [MART.]
SR-01000003035
NCGC00015841-02
CAS-306-07-0
Prestwick_377
Eutonyl (TN)
Hydrochloride, Pargyline
Opera_ID_404
N-Methyl-N-propargylbenzylamineHydrochloride
MLS001076511
Pargyline hydrochloride, 99%
SCHEMBL121111
2-Propynylamine, hydrochloride
PARGYLINE HYDROCHLORIDE?
CHEMBL1200425
HMS1568F07
Pharmakon1600-01500462
BCP21320
HY-A0091
PARGYLINE HYDROCHLORIDE [MI]
Tox21_110241
Tox21_302678
Tox21_501022
CCG-40239
NSC757264
s3690
AKOS015950558
Tox21_110241_1
FM41823
LP01022
NSC-757264
PARGYLINE HYDROCHLORIDE [VANDF]
WLN: 1UU2N1 & 1R & GH
PARGYLINE HYDROCHLORIDE [WHO-DD]
NCGC00015841-11
NCGC00094313-01
NCGC00094313-02
NCGC00094313-03
NCGC00256654-01
NCGC00261707-01
AC-18917
AC-38070
AS-16929
SY005867
DB-047811
EU-0101022
NS00079435
PARGYLINE HYDROCHLORIDE [ORANGE BOOK]
BIM-0050995.0001
D02564
P 8013
A820454
PARGYLINE HYDROCHLORIDE COMPONENT OF EUTRON
N-benzyl-N-methylprop-2-yn-1-amine;hydron;chloride
SR-01000003035-2
SR-01000003035-7
Q27292421
SR-01000003035-11
N-methyl-N-(phenylmethyl)-2-propyn-1-amine hydrochloride
N-methyl-N-(phenylmethyl)prop-2-yn-1-amine hydrochloride
206-175-1
N-benzyl-N-methylprop-2-yn-1-amine hydrochloride; Eutonyl-ten; N-Methyl-N-propargylbenzylamine hydrochloride; Pargyline HCl