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N-butyl-2-hydroxy-3-phenyl-benzamide

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Identification
Molecular formula
C17H19NO2
CAS number
27692-89-7
IUPAC name
N-butyl-2-hydroxy-3-phenyl-benzamide
State
State

At room temperature, N-butyl-2-hydroxy-3-phenyl-benzamide is typically found in a solid state.

Melting point (Celsius)
115.00
Melting point (Kelvin)
388.15
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.15
General information
Molecular weight
285.34g/mol
Molar mass
285.3500g/mol
Density
1.1049g/cm3
Appearence

N-butyl-2-hydroxy-3-phenyl-benzamide is a colorless to pale yellow crystalline solid. It has a slightly glossy appearance and can also be found as a powder depending on its purity and processing methods.

Comment on solubility

Solubility of N-butyl-2-hydroxy-3-phenyl-benzamide

N-butyl-2-hydroxy-3-phenyl-benzamide, a compound featuring both hydrophobic and hydrophilic functional groups, presents interesting characteristics regarding its solubility.

  • Hydrophobic Properties: The presence of the butyl group and the phenyl ring contributes significantly to the hydrophobicity of the compound, which can hinder solubility in polar solvents.
  • Hydrophilic Properties: The hydroxyl group (-OH) introduces some hydrophilicity, allowing for potential interactions with water molecules, which can enhance solubility to a degree.

In general, we can expect N-butyl-2-hydroxy-3-phenyl-benzamide to exhibit moderate solubility in polar organic solvents such as:

  • Alcohols (e.g., methanol, ethanol)
  • Aromatic hydrocarbons (e.g., toluene)

However, its solubility in water may be limited due to the predominance of the hydrophobic regions. It has been noted that:

"Solubility is often dictated by the balance between the hydrophobic and hydrophilic character of the molecules."

Ultimately, the solubility behavior of N-butyl-2-hydroxy-3-phenyl-benzamide can provide insight into its applicability and behavior in various chemical environments.

Interesting facts

Interesting Facts about N-butyl-2-hydroxy-3-phenyl-benzamide

N-butyl-2-hydroxy-3-phenyl-benzamide is a fascinating compound that has garnered attention in both pharmaceutical and chemical research. Here are some intriguing aspects of this compound:

  • Structure and Functionality: The compound features a benzamide backbone with a hydroxy group and a butyl side chain, which contributes to its unique properties. The presence of both hydrophobic and hydrophilic components enables versatile interactions with biological systems.
  • Potential Applications: Due to its structural characteristics, N-butyl-2-hydroxy-3-phenyl-benzamide may serve as a potential candidate in drug development, particularly for therapies targeting specific receptors in the body.
  • Analgesic and Anti-inflammatory Properties: Compounds similar to this structure have been explored for their ability to alleviate pain and reduce inflammation. This makes N-butyl-2-hydroxy-3-phenyl-benzamide a compound of interest in the search for new analgesics.
  • Research Gateways: Ongoing studies may reveal additional biological activities, including antimicrobial and antioxidant effects, potentially broadening its application in medicinal chemistry.
  • Importance of Substituents: The positioning of the butyl and hydroxyl groups is crucial for the compound’s biological activity. Such modifications are a strong focus in medicinal chemistry, where small changes can lead to significant differences in efficacy.

In the words of a renowned chemist, "The beauty of chemistry lies in the subtle balance of structure and function." N-butyl-2-hydroxy-3-phenyl-benzamide encapsulates this idea perfectly, showcasing how its molecular architecture can influence its role in various chemical and biological processes.

This compound not only serves as a valuable resource for ongoing research but also represents the intricate relationship between chemical design and practical applications in science today.

Synonyms
BUTYLPHENAMIDE
131-90-8
Butyl phenamide
Salicylamide, N-butyl-3-phenyl-
N-butyl-2-hydroxy-3-phenylbenzamide
4Q9N876YAJ
Bynamid
N-BUTYL-2-HYDROXY-[1,1'-BIPHENYL]-3-CARBOXAMIDE
N-n-Butyl-3-phenylsalicylamide
BRN 3325247
UNII-4Q9N876YAJ
(1,1'-Biphenyl)-3-carboxamide, N-butyl-2-hydroxy-
starbld0030875
N-butyl-3-phenyl-salicylamide
CHEMBL2106081
DTXSID50927031
N-butyl-2-hydroxy-3-phenyl-benzamide
Q27260361
N-Butyl-2-hydroxy[1,1'-biphenyl]-3-carboximidic acid