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N-butyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide

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Identification
Molecular formula
C13H18N4O2
CAS number
87233-66-5
IUPAC name
N-butyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide
State
State

At room temperature, N-butyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide is generally in a solid state.

Melting point (Celsius)
174.10
Melting point (Kelvin)
447.30
Boiling point (Celsius)
452.50
Boiling point (Kelvin)
725.70
General information
Molecular weight
250.32g/mol
Molar mass
250.3150g/mol
Density
1.2150g/cm3
Appearence

This compound typically appears as a solid crystalline powder. The color can range from off-white to light yellow, depending on purity and specific syntheses methods used.

Comment on solubility

Solubility of N-butyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide

The solubility of N-butyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide can be influenced by several factors due to its complex structure. Here are some key points to consider:

  • Polarity: The presence of both hydrophobic (butyl group) and hydrophilic (carbonyl and amine groups) elements suggests varying degrees of solubility in different solvents.
  • Solvent Type: This compound may demonstrate better solubility in polar solvents (such as water or ethanol) due to the polar functional groups.
  • Concentration Effects: As with many organic compounds, the solubility can vary based on concentration, temperature, and the presence of other solutes.
  • Hydrogen Bonding: The potential for hydrogen bonding with solvents could enhance solubility, particularly in alcohols or amines.

In conclusion, while the specific solubility characteristics of N-butyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide may require empirical determination, understanding the interplay of its functional groups and their interaction with different solvents is crucial. As the saying goes, "Like dissolves like," so one must consider both the chemical structure and the environment to predict solubility effectively.

Interesting facts

Interesting Facts about N-butyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide

N-butyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide is a fascinating compound that combines elements of medicinal chemistry and organic synthesis. Here are some key points that highlight its significance:

  • Pharmacological Potential: This compound belongs to a class of hydrazine derivatives that exhibit diverse biological activities, making them potential candidates for drug development. Studies have shown that similar compounds can possess anticancer properties or act as enzyme inhibitors.
  • Pyridine Influence: The inclusion of a pyridine ring within its structure is noteworthy. Pyridine derivatives are known for their ability to interact with a variety of biological targets, which can lead to promising therapeutic implications.
  • Synthetic Versatility: The synthesis of N-butyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide may involve various organic reactions, showcasing the versatility of hydrazine chemistry. This opens pathways to explore modifications that could enhance its efficacy or reduce side effects.
  • Research Applications: This compound can serve as a template for exploring structure-activity relationships (SAR) in drug discovery, allowing chemists to tweak functional groups to optimize performance.
  • Complexity and Uniqueness: The chemical structure of this compound features multiple functional groups that contribute to its unique properties. The balance between hydrophobic and hydrophilic regions can significantly impact its biological interactions.

In summary, N-butyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide is an intriguing compound that represents the intersection of organic synthesis and medicinal chemistry. Its complex structure and potential applications in pharmaceuticals highlight the continuous need for innovative research in this field.

Synonyms
P 1391
BRN 0487068
ISONICOTINIC ACID, 2-(2-(BUTYLCARBAMOYL)ETHYL)HYDRAZIDE
13012-73-2
DTXSID00156354
DTXCID8078845
SCHEMBL2999218