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Gramine

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Identification
Molecular formula
C12H18N2
CAS number
87-52-5
IUPAC name
N-butyl-N-[2-(1H-indol-3-yl)ethyl]butan-1-amine
State
State

At room temperature, Gramine is in a solid state.

Melting point (Celsius)
132.00
Melting point (Kelvin)
405.15
Boiling point (Celsius)
337.00
Boiling point (Kelvin)
610.15
General information
Molecular weight
204.29g/mol
Molar mass
204.3150g/mol
Density
1.0250g/cm3
Appearence

Gramine appears as a colorless solid that may exhibit crystalline forms. It is known for its solid structure at room temperature.

Comment on solubility

Solubility of N-butyl-N-[2-(1H-indol-3-yl)ethyl]butan-1-amine

The solubility of N-butyl-N-[2-(1H-indol-3-yl)ethyl]butan-1-amine is a noteworthy aspect of its chemical behavior and practical applications. This compound, with its complex structure, generally exhibits certain characteristics in various solvent systems. Here are some key points to consider:

  • Polar Solvents: N-butyl-N-[2-(1H-indol-3-yl)ethyl]butan-1-amine tends to have lower solubility in polar solvents due to its long hydrocarbon chains which make it more lipophilic.
  • Non-Polar Solvents: In contrast, this compound is likely to be more soluble in non-polar organic solvents such as hexane or toluene, where it can interact favorably.
  • Temperature Influence: The solubility may increase with temperature, a common behavior observed in organic compounds, where increased kinetic energy allows for better dispersion in the solvent.

In practical applications, the solubility behavior is crucial as it influences the compound’s bioavailability and efficacy in pharmaceutical formulations. As noted by many researchers, "the solubility of a compound often dictates its utility in various chemical processes and biological systems." Understanding the solubility profile of N-butyl-N-[2-(1H-indol-3-yl)ethyl]butan-1-amine can help chemists tailor its use in various fields such as drug design and material science.

Interesting facts

Discovering N-butyl-N-[2-(1H-indol-3-yl)ethyl]butan-1-amine

N-butyl-N-[2-(1H-indol-3-yl)ethyl]butan-1-amine, often referred to in the context of biochemistry and pharmacology, is a fascinating compound with potential implications in various fields. Here are some intriguing aspects of this compound:

  • Pharmacological Significance: This compound contains both butyl and indole moieties, which are known for their role in pharmacological activity. Indole derivatives are particularly notable for their biological activity, ranging from anti-inflammatory to anti-cancer effects.
  • Indole Structure: The presence of the indole ring in this compound enhances its ability to interact with various biological targets. Indoles are a common scaffold in drug design, thereby increasing the compound's appeal in medicinal chemistry.
  • Amine Functionality: The butan-1-amine component suggests that this compound may display amine-like properties, promoting its relevance in organic synthesis as a building block for more complex molecules.
  • Potential Neuroactive Properties: Given the structure of this compound, it may exhibit neuroactive properties. Compounds with similar structures have been studied for their effects on neurotransmitter systems, which makes this particular molecule of interest in neuropharmacology.

As with many compounds in pharmacology, the detailed study of N-butyl-N-[2-(1H-indol-3-yl)ethyl]butan-1-amine is essential not only for understanding its efficacy but also for its safety profile. Researchers continue to explore its full potential as a medicinal agent, thereby expanding our knowledge of indole-based compounds in drug development.

In summary, the unique combination of structural components in N-butyl-N-[2-(1H-indol-3-yl)ethyl]butan-1-amine positions it as a valuable compound in the search for new therapeutic agents. The ongoing research into its chemical properties and biological effects opens a window into innovative treatments in the medical field.

Synonyms
N,N-Dibutyltryptamine
DIBUTYLTRYPTAMINE
N-butyl-N-[2-(1H-indol-3-yl)ethyl]butan-1-amine
QFE8WT8WCW
1H-Indole-3-ethanamine, N,N-dibutyl-
DTXSID40166255
N-BUTYL-N-(2-(1H-INDOL-3-YL)ETHYL)BUTAN-1-AMINE
DTXCID1088746
15741-77-2
N,?N-?Dibutyltryptamine
N,N-Dibutyltryptamin
UNII-QFE8WT8WCW
SCHEMBL20970873
SCHEMBL29633016
DB-082954
Q5272303