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N-butylbenzenesulfonamide

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Identification
Molecular formula
C10H15NO2S
CAS number
3622-84-2
IUPAC name
N-butylbenzenesulfonamide
State
State

At room temperature, N-butylbenzenesulfonamide is a solid compound.

Melting point (Celsius)
49.00
Melting point (Kelvin)
322.15
Boiling point (Celsius)
186.00
Boiling point (Kelvin)
459.15
General information
Molecular weight
213.29g/mol
Molar mass
213.2940g/mol
Density
1.1551g/cm3
Appearence

N-butylbenzenesulfonamide is a colorless to pale yellow solid compound. It is typically found in a crystalline form, giving it an aesthetically uniform and clean appearance.

Comment on solubility

Solubility of N-butylbenzenesulfonamide

N-butylbenzenesulfonamide, with its chemical formula C12H17N1O2S1, exhibits intriguing solubility characteristics. Its solubility can be attributed to its functional groups and overall molecular structure. Here are some key points regarding its solubility:

  • Polarity: N-butylbenzenesulfonamide has a sulfonamide group that enhances its ability to interact with polar solvents.
  • Solvent Compatibility: It is expected to be soluble in polar organic solvents such as ethanol and dimethyl sulfoxide (DMSO), but may have limited solubility in non-polar solvents like hexane.
  • Temperature Effects: Increased temperatures typically improve solubility; thus, heating the solvent may facilitate the dissolution process.
  • Hydrogen Bonding: The presence of sulfonamide may allow for hydrogen bonding with water, potentially leading to moderate solubility in aqueous solutions.

In conclusion, while N-butylbenzenesulfonamide shows notable solubility in various solvents due to its structural components, the exact solubility can vary based on the solvent type and environmental conditions. Understanding these aspects is crucial for applications in chemical synthesis and formulation.

Interesting facts

Interesting Facts about N-butylbenzenesulfonamide

N-butylbenzenesulfonamide is a fascinating compound that showcases unique properties and applications, making it an intriguing topic of study for chemists and students alike.

Key Characteristics

  • Structure: This compound features a sulfonamide functional group, which is known for its diverse biological activities.
  • Applications: N-butylbenzenesulfonamide is often used in the pharmaceutical industry as an intermediate for the synthesis of various active pharmaceutical ingredients (APIs).
  • Biological Relevance: Sulfonamides have a significant history in medicine, notably as antibiotics, emphasizing their potential in therapeutic applications.
  • Physical Properties: The butyl group enhances its hydrophobic characteristics, which can influence how it interacts with biological systems.

Research Insights

According to several studies, compounds like N-butylbenzenesulfonamide have been recognized for their ability to inhibit certain enzymes, leading to important implications in drug development. “The potential of sulfonamides in medicinal chemistry is vast, as they can serve as scaffolds for new ligands and therapeutic agents.”

Environmental and Safety Considerations

As with many chemical compounds, understanding the environmental impact and safety measures associated with N-butylbenzenesulfonamide is crucial. It is essential to handle this compound with care, following appropriate safety protocols to minimize exposure risks.

This compound exemplifies how a chemical with a seemingly simple structure can play a significant role in advanced scientific research. Its multi-faceted applications and importance in medicinal chemistry make it a compound worth studying!

Synonyms
N-BUTYLBENZENESULFONAMIDE
3622-84-2
Benzenesulfonamide, N-butyl-
Plastomoll BMB
N-BUTYL-BENZENESULFONAMIDE
Dellatol BBS
Plasthall BSA
Cetamoll BMB
N-Butylbenzenesulphonamide
Benzenesulfonic acid butyl amide
N-Butylbenzene sulfonamide
Uniplex 214
BM 4 (sulfonamide)
N-(n-Butyl)benzenesulfonamide
NSC 3536
EINECS 222-823-6
DTXSID7027540
BRN 2725965
YO7UAW6717
CHEBI:44237
AI3-08011
NSC-3536
DTXCID907540
EC 222-823-6
4-11-00-00051 (Beilstein Handbook Reference)
222-823-6
NButylsulfonamid
NButylbenzenesulphonamide
NnButylbenzenesulfonamide
NButylbenzene sulfonamide
NButylbenzolsulfonsaureamid
Benzenesulfonamide, Nbutyl
nButylamide of benzenesulphonic acid
NnButylamide of benzenesulphonic acid
N-n-Butylbenzenesulfonamide
N-Butylbenzenesulfonamide-d9
N-n-Butyl benzenesulfonamide
UNII-YO7UAW6717
NBB
CAS-3622-84-2
N- butylbenzenesulfonamide
MFCD00025024
N-Benzenesulfonylbutylamine
3cz1
Cambridge id 5182395
SCHEMBL51729
CHEMBL479880
N-Butylbenzenesulfonamide, 99%
NSC3536
3d78
HMS3604D04
Tox21_201692
Tox21_303184
AKOS000120870
CS-W014968
DB02055
MS-7234
NCGC00164214-01
NCGC00164214-02
NCGC00256957-01
NCGC00259241-01
AC-12448
DB-080953
B0716
NS00007746
EN300-15785
D70361
AB00037309-01
AB00037309-02
N-butylbenzenesulphonamide; N-butylbenzenesulfonamide
Q14853448
Z45516915
F1113-0008
benzenesulfonamide, n-butyl-;n-butylbenzenesulfonamide;n-butylbenzenesulphonamide;benzenesulfonamide, n-butyl- n-butylbenzenesulfonamide n-butylbenzenesulphonamide
InChI=1/C10H15NO2S/c1-2-3-9-11-14(12,13)10-7-5-4-6-8-10/h4-8,11H,2-3,9H2,1H