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N-butylformamide

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Identification
Molecular formula
C5H11NO
CAS number
592-45-0
IUPAC name
N-butylformamide
State
State

At room temperature, N-butylformamide is a colorless to slightly yellow, oily liquid. It is fairly stable under normal conditions.

Melting point (Celsius)
-60.90
Melting point (Kelvin)
212.25
Boiling point (Celsius)
204.50
Boiling point (Kelvin)
477.65
General information
Molecular weight
115.16g/mol
Molar mass
115.1610g/mol
Density
0.9114g/cm3
Appearence

N-butylformamide is a clear liquid with a slightly yellowish tint. It has an amide-like odor, which is typical for compounds in this category. Due to its nature, it may be viscous and oily to the touch.

Comment on solubility

Solubility of N-butylformamide

N-butylformamide, with the chemical formula C5H11NO, exhibits interesting solubility characteristics. This compound is a relatively polar amide, which significantly affects its behaviour in various solvents.

Solubility Characteristics:

  • Water Solubility: N-butylformamide is soluble in water due to its polar functional groups which facilitate hydrogen bonding with water molecules.
  • Organic Solvents: This compound is also soluble in many organic solvents such as ethanol, methanol, and acetone, making it versatile in synthetic and extraction processes.
  • Solvent Polarity: The solubility of N-butylformamide tends to increase with the polarity of the solvent. It demonstrates a notable affinity for solvents that can engage in dipole-dipole interactions.

In summary, the solubility profile of N-butylformamide underscores its polar nature, allowing it to interact efficiently with both polar and non-polar solvents to a reasonable extent, thus expanding its utility in various chemical applications.

Interesting facts

N-butylformamide: A Unique Chemical Compound

N-butylformamide is a fascinating compound that falls under the category of amides, specifically an aliphatic amide. This compound is particularly notable for its versatile applications and unique properties, which make it an interesting subject of study in the field of chemistry.

Key Characteristics and Applications

  • Versatile Solvent: N-butylformamide is often utilized as a solvent in various chemical reactions due to its ability to dissolve both polar and nonpolar substances effectively.
  • Intermediate in Synthesis: This compound acts as a key intermediate in the synthesis of pharmaceuticals and agricultural chemicals, making it a valuable asset in drug development.
  • Polymer Industry: N-butylformamide is also used in the production of various polymers, which highlights its significance in materials science.
  • Biological Activity: Studies have shown that certain derivatives of N-butylformamide exhibit biological activity, which opens doors for potential new therapeutic agents.

Chemical Behavior and Properties

From a chemical perspective, N-butylformamide displays interesting reactivity with a variety of compounds. Here are some additional insights:

  • It can undergo hydrolysis, leading to the formation of butylamine and formic acid.
  • The compound’s structure, featuring both a carbonyl and an amino group, enables it to participate in a range of chemical reactions, including condensation and acylation.
  • The presence of the butyl group contributes to its moderate hydrophobic nature, influencing its compatibility with different solvents.

With its diverse chemical properties and practical applications, N-butylformamide stands out as an important compound in both academic research and industrial applications. Scientists and students alike can appreciate the compound's role in advancing our understanding of organic chemistry and its applications in various fields.

As the renowned chemist Linus Pauling once said, "Chemistry is the science of matter, and the study of matter is the study of our world." N-butylformamide is a perfect example of how chemistry impacts both our environment and our progress in science.

Synonyms
N-Butylformamide
Butylformamide
N-n-Butylformamide
Formamide, N-butyl-
FORMAMIDE, N-n-BUTYL-
NSC 5939
UNII-S17P62W6IH
BRN 1700042
S17P62W6IH
CHEBI:84287
AI3-04127
NSC-5939
DTXSID10236131
4-04-00-00564 (Beilstein Handbook Reference)
NnButylformamide
Formamide, Nbutyl
Formamide, Nnbutyl
DTXCID10158622
qqgnlkjaivsnco-uhfffaoysa-n
871-71-6
N-Butyl-formamide
CHEMBL45466
NSC5939
WLN: VHM4
SCHEMBL26602
BDBM50064269
AKOS006274295
DB-318869
EN300-211463
Q27157653