Interesting facts
N-chloro-4-methyl-benzenesulfonamide
N-chloro-4-methyl-benzenesulfonamide is a fascinating compound that combines elements of organic chemistry and synthetic applications. Here are some interesting facts about this compound that every chemistry student should know:
- Structure and Stability: The compound features a sulfonamide group, which plays a critical role in its reactivity and biological activity. The presence of a chlorine atom adds to its unique properties, impacting the stability and interaction of the molecule.
- Biological Relevance: Sulfonamides are vital in medicinal chemistry, as they were among the first antibiotics used to treat bacterial infections. Although N-chloro-4-methyl-benzenesulfonamide specifically does not have the same historical significance as the original sulfa drugs, it still provides a basis for exploring various modifications that can enhance antimicrobial properties.
- Applications in Research: This compound can serve as a synthetic intermediate in organic reactions. Scientists can utilize its unique functional groups to create more complex molecules for use in pharmaceuticals or agricultural products.
- Environmental Impact: Understanding the behavior of compounds like N-chloro-4-methyl-benzenesulfonamide is crucial for evaluating their ecological effects. Research into how such compounds persist in the environment helps form regulations and guidelines to mitigate their impact.
- Chemistry in Action: The reactivity of N-chloro-4-methyl-benzenesulfonamide can be demonstrated in various experimental settings, showcasing concepts like electrophilic aromatic substitution and nucleophilic attack. This makes it a useful example in organic chemistry coursework.
In conclusion, N-chloro-4-methyl-benzenesulfonamide exemplifies the intricate balance between structure and function in chemical compounds. By studying such molecules, chemists continue to unlock new possibilities in synthesis, medicine, and environmental science.
Synonyms
N-Chloro-p-toluenesulfonamide
tosylchloramide
144-86-5
UF17KA8AC5
p-Toluenesulfonamide, N-chloro-
TOSYLCHLORAMIDE [WHO-DD]
n-chloro-4-methyl-benzenesulfonamide
RefChem:898633
N-chloro-4-methylbenzenesulfonamide
Benzenesulfonamide, N-chloro-4-methyl-
N-chlorotoluene-p-sulfonamide
CHEBI:53782
UNII-UF17KA8AC5
N-chloro-4-methylbenzene-1-sulfonamide
SCHEMBL43534
CHEMBL1625750
DTXSID9047627
NXTVQNIVUKXOIL-UHFFFAOYSA-N
AKOS004909750
DB14708
NS00005965
EN300-215534
SR-01000944411
SR-01000944411-1
BRD-K93546328-236-02-8
Q27124208
Solubility of N-chloro-4-methyl-benzenesulfonamide
N-chloro-4-methyl-benzenesulfonamide, a sulfonamide derivative, exhibits specific solubility characteristics that are essential for its applications in pharmaceuticals and chemistry. The solubility of this compound is greatly influenced by several factors:
Overall, while N-chloro-4-methyl-benzenesulfonamide can be soluble in polar solvents, it is essential to consider the various parameters that can affect its solubility. As stated, "solubility is a key factor influencing the biological activity and therapeutic efficacy of chemical compounds." This emphasizes the importance of understanding solubility in the context of drug development and other applications.