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Chloramine-T

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Identification
Molecular formula
C7H7ClNO2S
CAS number
127-65-1
IUPAC name
N-chlorobenzenesulfonamide
State
State

At room temperature, Chloramine-T is typically a solid. This hygroscopic crystalline powder is stable under standard atmospheric conditions but should be stored in airtight containers to prevent moisture absorption.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
227.64g/mol
Molar mass
227.6400g/mol
Density
1.4000g/cm3
Appearence

Chloramine-T typically appears as a white to off-white crystalline powder. It is quite distinct due to its fine granular texture when observed closely. When in solid form, it may exhibit slight hygroscopic properties, attracting moisture from the air.

Comment on solubility

Solubility of N-chlorobenzenesulfonamide

N-chlorobenzenesulfonamide, with the chemical formula C6H6ClNO2S, presents interesting solubility characteristics that are worth exploring. This compound typically exhibits the following behavior:

  • Solvent Interaction: N-chlorobenzenesulfonamide is generally soluble in polar solvents such as water, given its sulfonamide group, which can engage in hydrogen bonding.
  • Organic Solvents: It also displays solubility in organic solvents like methanol and ethanol due to the presence of the aromatic ring and the polar nature of the sulfonamide group.
  • Temperature Dependency: Like many sulfonamides, the solubility of N-chlorobenzenesulfonamide can be affected by temperature; higher temperatures typically lead to increased solubility.

In practical terms, this means that when preparing solutions of N-chlorobenzenesulfonamide, a chemist might find it convenient to select a solvent based on the desired application. For instance, “Choosing the right solvent can significantly impact the efficiency of chemical reactions involving N-chlorobenzenesulfonamide.

Overall, while N-chlorobenzenesulfonamide demonstrates notable solubility in various solvents, understanding these interactions is crucial for its effective application in chemical processes.

Interesting facts

Interesting Facts About N-Chlorobenzenesulfonamide

N-chlorobenzenesulfonamide, a fascinating compound in the field of organic chemistry, holds significant relevance in both industrial applications and pharmaceutical research. This compound is primarily used as a reagent in various organic syntheses, showcasing its versatility and utility. Here are some intriguing aspects of N-chlorobenzenesulfonamide:

  • Pharmaceutical Importance: N-chlorobenzenesulfonamide is notable for its role in medicinal chemistry, where it acts as an intermediary in the synthesis of sulfa drugs, a class of antibiotics that revolutionized the treatment of bacterial infections.
  • Antimicrobial Properties: The sulfonamide group is known for its antimicrobial properties, making compounds like N-chlorobenzenesulfonamide useful in combating various infections, highlighting the compound's significance in healthcare.
  • Chemical Reactivity: This compound's reactivity is particularly interesting; it can participate in various substitution reactions, allowing chemists to modify its structure and enhance its efficacy for specific applications.
  • Synthetic Routes: Chemists have developed several synthetic routes to produce N-chlorobenzenesulfonamide, emphasizing the importance of understanding different methodologies in organic synthesis.

In the realm of research and development, compounds like N-chlorobenzenesulfonamide provide a wealth of opportunities for innovation. As one scientist aptly noted, "Understanding the structure and reactivity of compounds like N-chlorobenzenesulfonamide is key to unlocking new therapeutic potentials." This compound continues to be a subject of study, proving that even small modifications can lead to significant advancements in chemistry and medicine.

Synonyms
N-Chlorobenzenesulfonamide
80-16-0
Phenylsulfamyl chloride
59521MS4CG
RefChem:927087
Chlordetal
UNII-59521MS4CG
AI3-00817
SCHEMBL238411
orb1697829
SCHEMBL1827999
SCHEMBL1828000
SCHEMBL2687422
AKOS006278416
BENZENSULFONCHLORAMIDE [WHO-DD]
NS00040878
EN300-218228
Q27261655