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N-Cyclohexylbenzamide

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Identification
Molecular formula
C13H17NO
CAS number
866-94-2
IUPAC name
N-cyclohexylbenzamide
State
State

N-Cyclohexylbenzamide is in a solid state at room temperature. It appears as a stable crystalline powder, exhibiting typical characteristics of amide compounds. The solid state allows it to be handled easily in laboratory environments and for various chemical applications.

Melting point (Celsius)
118.00
Melting point (Kelvin)
391.15
Boiling point (Celsius)
182.00
Boiling point (Kelvin)
455.15
General information
Molecular weight
203.29g/mol
Molar mass
203.2920g/mol
Density
1.0645g/cm3
Appearence

N-Cyclohexylbenzamide typically appears as a white or off-white crystalline powder. Its crystals may vary in size and shape depending on the conditions of crystallization, but they are generally uniform and stable under standard conditions. The compound's appearance is typical for many solid amides, with a texture that may feel slightly granular to the touch.

Comment on solubility

Solubility of N-cyclohexylbenzamide

N-cyclohexylbenzamide, with the chemical formula C13H17NO, exhibits interesting solubility characteristics that are vital for its applications. Understanding these can help in various fields such as medicinal chemistry and organic synthesis.

Solubility in Common Solvents

This compound is primarily soluble in organic solvents, which include:

  • Ethyl acetate
  • Dimethyl sulfoxide (DMSO)
  • Acetone

These solvents are often used for dissolving organic compounds due to their ability to interact favorably with non-polar moieties.

Limited Aqueous Solubility

In contrast, N-cyclohexylbenzamide has very low solubility in water. This characteristic can be attributed to:

  • Its hydrophobic cyclohexyl ring, which increases the non-polar characteristics of the molecule.
  • The absence of significant polar functional groups that could form hydrogen bonds with water.

As a result, it is often recommended to avoid using water as a solvent when working with this compound.

Importance of Solubility

Understanding the solubility of N-cyclohexylbenzamide is crucial for:

  • Determining its interactions in biological systems.
  • Guiding the choice of solvents in laboratory applications.
  • Predicting its behavior in environmental contexts, particularly in relation to bioaccumulation.

In summary, while N-cyclohexylbenzamide shows beneficial solubility in various organic solvents, its limited solubility in water highlights the importance of careful solvent selection in its handling and application.

Interesting facts

Interesting Facts about N-cyclohexylbenzamide

N-cyclohexylbenzamide is an intriguing compound that has garnered attention in both academic research and industrial applications. Here are some notable facts that highlight its significance:

  • Chemical Structure: The compound features a unique structure that consists of a cyclohexyl group attached to a benzamide moiety. This configuration plays a crucial role in its chemical reactivity and physical properties.
  • Pharmaceutical Potential: N-cyclohexylbenzamide has been investigated for its potential use in medicinal chemistry. Its structure allows for interactions with various biological targets, making it a candidate for drug development.
  • Research Applications: This compound has become a focus for researchers studying the mechanisms of amide bond formations and their implications in the synthesis of complex organic molecules.
  • Chemical Behavior: Due to the presence of both a cyclic alkane and an aromatic system, N-cyclohexylbenzamide displays interesting solubility characteristics that may affect its behavior in different solvents.
  • Environmentally Relevant: Studies have shown that compounds like N-cyclohexylbenzamide can be significant in understanding environmental pollution, particularly in how amides behave in different ecological conditions.

In conclusion, N-cyclohexylbenzamide is more than just a molecule; it represents a convergence of chemistry and potential usability in various scientific fields. As we explore this compound further, we can expect to uncover more about its properties and capabilities.

Synonyms
N-Cyclohexylbenzamide
N-Benzoylcyclohexylamine
Hexamethylenebenzamide
BENZAMIDE, N-CYCLOHEXYL-
UNII-Q3GK2CZL0R
Q3GK2CZL0R
NSC 4632
P-401
BRN 1873469
AI3-01429
NSC-4632
N-HEXAMETHYLENEBENZAMIDE
DTXSID70170042
4-12-00-00043 (Beilstein Handbook Reference)
1',2',3',4',5',6'-HEXAHYDROBENZANILIDE
DTXCID5092533
843-044-3
kqjydhwnypriry-uhfffaoysa-n
1759-68-8
N-cyclohexyl-benzamide
NSC4632
MFCD00452187
MLS006027070
SCHEMBL307051
BAA75968
STL253079
AKOS002259322
AS-77733
SMR001495922
D85671
EN300-138387
Q15628307
Z31484290