Skip to main content

N-(cyclohexylideneamino)-4-nitro-benzamide

ADVERTISEMENT
Identification
Molecular formula
C13H14N3O3
CAS number
5485-64-3
IUPAC name
N-(cyclohexylideneamino)-4-nitro-benzamide
State
State

N-(cyclohexylideneamino)-4-nitro-benzamide would be a solid at room temperature. The presence of the aromatic ring and nitro group contributes to a high melting point consistent with a solid crystalline structure.

Melting point (Celsius)
189.00
Melting point (Kelvin)
462.15
Boiling point (Celsius)
405.00
Boiling point (Kelvin)
678.15
General information
Molecular weight
289.30g/mol
Molar mass
289.3390g/mol
Density
1.2930g/cm3
Appearence

N-(cyclohexylideneamino)-4-nitro-benzamide typically appears as a crystalline solid. The color is generally pale yellow, often indicative of the nitro groups present in the compound. The solid nature suggests a degree of rigidity in its structure due to the aromatic benzamide and the cyclohexylidene moiety.

Comment on solubility

Solubility of N-(cyclohexylideneamino)-4-nitro-benzamide

N-(cyclohexylideneamino)-4-nitro-benzamide, a compound with a complex molecular structure, exhibits unique solubility characteristics influenced by its functional groups and molecular interactions. Understanding its solubility is essential for applications in pharmaceuticals and material sciences.

Factors Influencing Solubility:

  • Polarity: The presence of polar functional groups can significantly affect solubility. In the case of this compound, the nitro group contributes to its polarity, which may enhance solubility in polar solvents.
  • Hydrophobic Interactions: The cyclohexyl group introduces hydrophobic characteristics, suggesting that N-(cyclohexylideneamino)-4-nitro-benzamide might have limited solubility in water but could be better dissolved in organic solvents.
  • Hydrogen Bonding: The amide group can participate in hydrogen bonding, potentially allowing for better solubility in solvents capable of forming such interactions.

As a general rule, compounds like N-(cyclohexylideneamino)-4-nitro-benzamide might be more soluble in:

  • Organic solvents such as DMSO, DMF, or ethanol
  • Aqueous solutions with the presence of surfactants or co-solvents that enhance solubility

In summary, while the solubility of N-(cyclohexylideneamino)-4-nitro-benzamide may not be straightforward, considering the interplay of its functional groups and molecular properties provides valuable insights. Knowing its solubility behavior is crucial for its practical applications and effectiveness in various fields.

Interesting facts

N-(Cyclohexylideneamino)-4-nitro-benzamide

N-(Cyclohexylideneamino)-4-nitro-benzamide, a compound with intriguing properties, has garnered attention in various fields, including medicinal chemistry and organic synthesis. Here are some interesting facts about this chemical:

  • Structural Significance: This compound is characterized by the presence of both a nitro group and an amide group, contributing to its potential reactivity. Its unique structure may lead to interesting interactions in biological systems.
  • Biological Activity: Compounds with similar structures have been investigated for their pharmacological properties. Research has suggested that amide derivatives can exhibit antimicrobial, anti-inflammatory, and even anticancer activities.
  • Cyclohexylidene Group: The presence of the cyclohexylidene moiety enhances the lipophilicity of the compound, which can be advantageous for enhancing bioavailability and molecular interactions in drug development.
  • Application Potential: Given its structural components, this compound could be explored as a lead compound in drug discovery or as a molecular probe in the study of enzyme mechanisms.
  • Reaction Pathways: The functional groups present in this compound make it valuable for various organic reactions, potentially leading to the synthesis of more complex molecules. Many researchers enjoy exploring the diverse pathways of amides and nitro compounds in synthetic applications.

In summary, N-(cyclohexylideneamino)-4-nitro-benzamide showcases the fascinating interplay between structure and function in chemical compounds, serving as a reminder of how small changes in molecular architecture can lead to big differences in behavior and utility. As scientific research continues to uncover its potential, this compound may pave the way for new innovations in chemistry and medicine.

Synonyms
N-(cyclohexylideneamino)-4-nitrobenzamide
329-84-0
BENZOIC ACID, p-NITRO-, CYCLOHEXYLIDENEHYDRAZIDE
p-Nitrobenzoic acid cyclohexylidene hydrazide
KWJ99GYN8Q
Benzoic acid, 4-nitro-, cyclohexylidenehydrazide
NSC-404147
NSC 404147
BRN 3372757
NSC404147
N'-cyclohexylidene-4-nitrobenzohydrazide
UNII-KWJ99GYN8Q
WLN: L6TJ AMMVR DNW
DTXSID80186553
AKOS002314497
4-NITROBENZOIC ACID 2-CYCLOHEXYLIDENEHYDRAZIDE
BENZOIC ACID, 4-NITRO-, 2-CYCLOHEXYLIDENEHYDRAZIDE