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N-(cyclopentylideneamino)-4-nitro-benzamide

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Identification
Molecular formula
C12H13N3O3
CAS number
1022-20-2
IUPAC name
N-(cyclopentylideneamino)-4-nitro-benzamide
State
State

This compound is typically in a solid state at room temperature.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
335.00
Boiling point (Kelvin)
608.15
General information
Molecular weight
246.27g/mol
Molar mass
246.2670g/mol
Density
1.2500g/cm3
Appearence

N-(cyclopentylideneamino)-4-nitro-benzamide is typically an off-white crystalline solid. The compound usually appears as a powder with a uniform texture. Due to its aromatic and nitro group components, it may exhibit a slight aromatic odor.

Comment on solubility

Solubility of N-(cyclopentylideneamino)-4-nitro-benzamide

N-(cyclopentylideneamino)-4-nitro-benzamide is an intriguing compound when it comes to its solubility characteristics. Understanding the solubility of this compound requires examining a few key factors:

  • Polarity: The presence of the nitro group (–NO2) suggests that this molecule may exhibit polar characteristics. This could influence its solubility in polar solvents.
  • Hydrogen Bonding: The amide functional group can act as both a hydrogen bond donor and acceptor, enhancing solubility in protic solvents. This feature is particularly relevant in solvents such as water or alcohols.
  • Cyclopentyl Group: The cyclopentyl ring may introduce hydrophobicity, potentially complicating solubility in highly polar solvents.

Typically, compounds with similar characteristics may exhibit varied solubility behaviors:

  1. If dealing with organic solvents, the solubility could be moderate to high due to the presence of the amide group.
  2. In aqueous solutions, solubility may be limited; however, some degree of solubility could be expected due to the polar nature of the nitro and amide functionalities.

In summary, while the solubility of N-(cyclopentylideneamino)-4-nitro-benzamide in various solvents will vary, it is essential to consider both its polar and non-polar components. An experimental approach is often necessary to ascertain precise solubility details in specific solvents.

Interesting facts

Interesting Facts about N-(Cyclopentylideneamino)-4-nitro-benzamide

N-(Cyclopentylideneamino)-4-nitro-benzamide is a fascinating chemical compound that serves as a representative of a class of organic molecules featuring significant biological activity. Below are some intriguing aspects that highlight its importance:

  • Structure and Function: The compound contains both a nitro group and an amide group, which can contribute to its unique reactivity and the ability to form hydrogen bonds. The presence of the cyclopentylidene group enhances its structural diversity.
  • Biological Relevance: Many compounds similar to N-(cyclopentylideneamino)-4-nitro-benzamide have been explored for their potential pharmacological effects, especially in cancer therapy and anti-inflammatory applications. This compound may exhibit similar properties due to its structural characteristics.
  • Synthetic Pathways: The synthesis of this compound often involves multi-step reactions, including amide formation and selective functional group modifications. Such synthetic strategies are a great example of organic chemistry's intersection with medicinal chemistry.
  • Analytical Techniques: Characterizing compounds like N-(cyclopentylideneamino)-4-nitro-benzamide typically requires a blend of analytical methods such as NMR spectroscopy, mass spectrometry, and infrared spectroscopy, enabling scientists to confirm their structure and purity.
  • Research Potential: Ongoing research may uncover novel applications for N-(cyclopentylideneamino)-4-nitro-benzamide in medicinal chemistry. As scientists continue to investigate its biological properties, it could lead to the development of new therapeutics.

In conclusion, N-(Cyclopentylideneamino)-4-nitro-benzamide exemplifies the intricate relationship between molecular structure and biological activity. Its diverse potential and the ongoing research surrounding it make it a subject of great interest in the fields of organic chemistry and pharmacology.

Synonyms
329-83-9
BENZOIC ACID, p-NITRO-, CYCLOPENTYLIDENEHYDRAZIDE
N'-cyclopentylidene-4-nitrobenzohydrazide
Benzoic acid, 4-nitro-, cyclopentylidenehydrazide
NSC-404146
N-(cyclopentylideneamino)-4-nitrobenzamide
NSC 404146
BRN 3353138
p-Nitrobenzoic acid cyclopentylidene hydrazide
benzoic acid, 4-nitro-, 2-cyclopentylidenehydrazide
NSC404146
E4YB2F3H6Y
CBDivE_008019
WLN: L5TJ AMMVR DNW
3-09-00-01753 (Beilstein Handbook Reference)
MLS000727959
CHEMBL1596840
DTXSID20186552
HMS2698E21
STK730857
AKOS002314498
NCGC00245889-01
SMR000306653
N-(cyclopentylideneamino)-4-nitro-benzamide
4-Nitrobenzoic acid 2-cyclopentylidenehydrazide
Benzoic acid, p-nitro-,cyclo-pentylidenehydrazide