Skip to main content

Cefaclor

ADVERTISEMENT
Identification
Molecular formula
C15H14N2O5S
CAS number
70356-03-5
IUPAC name
N-ethoxy-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxamide
State
State

At room temperature, Cefaclor is typically in a solid state, appearing as a crystalline powder. Its stability in this solid form allows it to be packaged and handled efficiently in pharmaceutical contexts.

Melting point (Celsius)
138.00
Melting point (Kelvin)
411.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
367.82g/mol
Molar mass
367.8220g/mol
Density
1.4900g/cm3
Appearence

Cefaclor appears as a white to off-white crystalline powder. It is practically insoluble in water, slightly soluble in methanol, and sparingly soluble in ethanol. Its appearance is consistent with similar cephalosporin antibiotics, which generally have a crystalline and white powdered form.

Comment on solubility

Solubility of N-ethoxy-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxamide

The solubility of N-ethoxy-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxamide is an interesting topic due to its complex molecular structure and functional groups. Understanding its solubility can be pivotal for various applications.

Factors Influencing Solubility

Several factors determine the solubility of this compound:

  • Polarity: The presence of polar functional groups, such as the carboxamide and ethoxy groups, can enhance solubility in polar solvents like water.
  • Hydrophobic regions: The presence of aromatic rings (like the phenylacetyl group) can create hydrophobic areas that may reduce solubility in aqueous environments.
  • Temperature: Increased temperatures generally increase solubility, particularly for organic compounds.

Predicted Solubility

Based on its structure, one might anticipate:

  • High solubility in: Organic solvents such as ethanol or DMSO due to its non-polar regions.
  • Limitations in: Aqueous solutions, although the polar groups may provide some solubility.

In conclusion, while exact solubility values are essential for practical applications, the structural components suggest a tendency towards solubility in certain organic solvents while potentially facing challenges in polar aqueous solutions. Therefore, it’s crucial to explore empirical data for precise solubility analysis.

Interesting facts

Overview of N-ethoxy-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxamide

N-ethoxy-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxamide is a fascinating compound belonging to the class of thiazolidinones. It boasts a unique bicyclic structure which adds to its reactivity and potential applications in various fields.

Interesting Facts

  • Antimicrobial Properties: This compound has been investigated for its antimicrobial activity and has shown promise against several pathogenic bacteria, which makes it a candidate for further pharmaceutical development.
  • Structural Complexity: The bicyclic architecture involves a thia and azabicyclic framework, which is relatively rare and allows for diverse chemical modifications. Such structural intricacies ultimately influence biological interactions and potential efficacy.
  • Drug Development: The incorporation of ethoxy and phenylacetyl moieties suggests potential bioactive properties, making it an interesting subject for studies in drug design and synthesis.
  • Research Implications: The unique combination of functional groups may lead researchers to explore its applications not just in medicinal chemistry, but also in agrochemistry and materials science, opening doors to innovative compounds.
  • Future Studies: Continuous research is warranted to better understand its mechanisms of action, potential therapeutic applications, and how modifications to its structure could enhance efficacy or reduce side effects.

As scientists continue to unravel the complexity of N-ethoxy-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxamide, its role in advancing medicinal chemistry and influencing future drug development remains intriguing. Its multifaceted nature exemplifies the importance of chemical exploration in the search for new therapeutic agents.

Synonyms
DTXSID50945356
N-Ethoxy-6-[(1-hydroxy-2-phenylethylidene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboximidic acid