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Pramipexole

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Identification
Molecular formula
C10H17N3S
CAS number
104632-26-0
IUPAC name
N-ethyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-3-carboximidothioic acid
State
State

At room temperature, Pramipexole is in the form of a solid powder. It is stable under standard conditions and should be stored away from excessive moisture and light.

Melting point (Celsius)
296.60
Melting point (Kelvin)
569.75
Boiling point (Celsius)
848.20
Boiling point (Kelvin)
1 121.35
General information
Molecular weight
211.33g/mol
Molar mass
211.3330g/mol
Density
1.1100g/cm3
Appearence

Pramipexole appears as a white to off-white powder. It is slightly soluble in water and very soluble in a range of organic solvents such as methanol, ethanol, and acetone.

Comment on solubility

Solubility of N-ethyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-3-carboximidothioic acid

The solubility of N-ethyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-3-carboximidothioic acid is an intriguing aspect to explore. This compound, with its complex structure, can exhibit varying solubility characteristics depending on several factors:

  • Polarity: The presence of the carboximidothioic acid group influences its polarity, potentially enhancing solubility in polar solvents.
  • Hydrogen Bonding: Ability to form hydrogen bonds may increase solubility in water and alcohols, as functional groups interact with solvent molecules.
  • Temperature: As with many organic compounds, solubility may improve with increased temperature, allowing for better dissolution.

In summary, while detailed empirical solubility data for N-ethyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-3-carboximidothioic acid may not be widely available, its structural features suggest that it could be soluble in polar solvents. As always, experimental verification under controlled conditions is essential to fully understand its solubility behavior.

Interesting facts

Interesting Facts about N-ethyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-3-carboximidothioic acid

N-ethyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-3-carboximidothioic acid is a fascinating compound that finds its significance in various fields of chemistry, particularly in pharmacology and organic synthesis. Here are some notable aspects of this intriguing molecule:

  • Structure and Complexity: This compound features a unique bicyclic structure, which is known for its strain and reactivity. The presence of the azabicyclo ring system contributes to the compound's interesting chemical behavior.
  • Potential Pharmaceutical Applications: Compounds like N-ethyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-3-carboximidothioic acid can serve as precursors for the development of new drugs due to their diverse functional groups. This can open doors for medications targeting various biological processes.
  • Thioic Acid Component: The incorporation of thioic acid functionality into the compound can enhance its interactions with biological systems, as thio groups are known to play crucial roles in various biochemical pathways.
  • Research and Discovery: The synthesis and characterization of such compounds are often subjects of research in organic chemistry labs, as scientists explore their properties and potential uses. This ongoing research can lead to significant breakthroughs in medicinal chemistry.
  • Cross-Disciplinary Interest: This compound exemplifies the interdisciplinary nature of modern chemistry, bridging organic chemistry, medicinal chemistry, and biochemistry, thereby appealing to a wide range of scientific disciplines.

As stated by renowned chemist Marie Curie, "Nothing in life is to be feared, it is only to be understood." Similarly, understanding the complexities and potential of compounds like N-ethyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane-3-carboximidothioic acid can pave the way for innovative applications in science and medicine.