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Venlafaxine

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Identification
Molecular formula
C17H27NO2
CAS number
93413-69-5
IUPAC name
N-ethyl-2-(2-methoxyphenyl)-N-(2-morpholinoethyl)ethanamine
State
State

Venlafaxine is typically found as a solid at room temperature. It is a pharmaceutical compound commonly used in its hydrochloride salt form due to increased solubility properties for drug formulation.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
694.80
Boiling point (Kelvin)
968.00
General information
Molecular weight
277.41g/mol
Molar mass
277.4140g/mol
Density
1.1120g/cm3
Appearence

Venlafaxine is typically seen as a crystalline solid. It is often provided in the form of tablets or capsules for pharmaceutical use. Pure venlafaxine is a solid at room temperature.

Comment on solubility

Solubility of N-ethyl-2-(2-methoxyphenyl)-N-(2-morpholinoethyl)ethanamine

The solubility of N-ethyl-2-(2-methoxyphenyl)-N-(2-morpholinoethyl)ethanamine can be influenced by various factors such as temperature, pH, and the chemical structure of the compound itself. This compound, with its complex structure, presents a unique set of solubility characteristics:

  • Solvent Compatibility: It is generally more soluble in organic solvents like ethanol, methanol, and DMSO compared to water.
  • Polar and Nonpolar Interactions: The presence of both polar and nonpolar groups in the molecule can lead to diverse solubility profiles. The methoxy group (−OCH3) increases its polarity, potentially enhancing solubility in polar solvents.
  • Temperature Effects: As is typical for many organic compounds, solubility may increase with temperature, making warm solvents more effective for dissolving this compound.
  • pH Sensitivity: Being an amine, its solubility could be affected by the pH of the solution, with higher solubility in acidic conditions where it can become protonated.

In summary, while N-ethyl-2-(2-methoxyphenyl)-N-(2-morpholinoethyl)ethanamine is less soluble in water, it shows promising solubility in organic solvents and can be effectively used in various applications due to its flexible solubility characteristics.

Interesting facts

Interesting Facts about N-ethyl-2-(2-methoxyphenyl)-N-(2-morpholinoethyl)ethanamine

N-ethyl-2-(2-methoxyphenyl)-N-(2-morpholinoethyl)ethanamine is a fascinating compound that has caught the attention of chemists and pharmacologists alike. Here are some noteworthy aspects of this chemical:

  • Origin: This compound belongs to a class of chemical entities known as amines, which play a critical role in various biological and chemical processes.
  • Potential Applications: Research indicates that compounds similar to this one are often explored for their medicinal properties, particularly in the context of neuropharmacology. Their unique structure may allow them to interact with various neurotransmitter systems in the brain.
  • Structural Diversity: The presence of both a methoxy group and a morpholino group enhances its structural complexity. This diversity can lead to a broad spectrum of biological activity, making it a valuable candidate for drug development.
  • Functional Groups: Featuring a morpholine ring, this compound exemplifies how cyclic amines can be integral to the functionality of pharmaceutical compounds, aiding in the modulation of drug interactions.
  • Research Interest: Scientists continue to investigate related compounds for their potential efficacy in treating conditions that involve altered neurotransmitter dynamics, including mood disorders and neurodegenerative diseases.

In summary, N-ethyl-2-(2-methoxyphenyl)-N-(2-morpholinoethyl)ethanamine represents more than just a chemical formula; it embodies the intersection of chemistry, biology, and medicine. As research progresses, we may uncover even more intriguing properties and applications for this compound, contributing to the advancement of therapeutic strategies in the healthcare sector.

Synonyms
N-ethyl-2-(2-methoxyphenyl)-N-(2-morpholin-4-ylethyl)ethanamine
84R965G63C
4-Morpholineethanamine, N-ethyl-N-[2-(2-methoxyphenyl)ethyl]-
N-Ethyl-N-[2-(2-methoxyphenyl)ethyl]-4-morpholineethanamine
3812-63-3