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N-ethyl-2-fluoro-N-(1-naphthyl)acetamide

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Identification
Molecular formula
C14H14FNO
CAS number
84393-84-8
IUPAC name
N-ethyl-2-fluoro-N-(1-naphthyl)acetamide
State
State
At room temperature, it is a solid with a stable crystalline structure.
Melting point (Celsius)
58.00
Melting point (Kelvin)
331.00
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.00
General information
Molecular weight
245.28g/mol
Molar mass
245.2750g/mol
Density
1.2270g/cm3
Appearence

N-ethyl-2-fluoro-N-(1-naphthyl)acetamide is typically a crystalline solid with a white to off-white appearance. Its structural integrity is maintained at room temperature, making it stable under standard conditions.

Comment on solubility

Solubility of N-ethyl-2-fluoro-N-(1-naphthyl)acetamide

N-ethyl-2-fluoro-N-(1-naphthyl)acetamide, characterized by its unique molecular structure, exhibits distinctive solubility properties. Understanding its solubility can be pivotal for applications in pharmaceuticals and chemical processes.

Key Points on Solubility

  • Polarity: The presence of the fluoro group and the naphthyl moiety affect the molecule's overall polarity, influencing its solubility in different solvents.
  • Solvent Interactions: This compound is likely to be soluble in organic solvents such as ethanol, acetone, and dimethyl sulfoxide (DMSO) due to hydrophobic interactions with the naphthyl group.
  • Aqueous Solubility: Conversely, solubility in water is expected to be limited, given the relatively non-polar characteristics imparted by the naphthyl structure.
  • Temperature Dependence: As with many organic compounds, solubility may increase with temperature, allowing for enhanced dissolution in organic solvents.

In summary, the solubility of N-ethyl-2-fluoro-N-(1-naphthyl)acetamide is largely influenced by its chemical structure, making it soluble in specific organic solvents while likely exhibiting reduced solubility in polar solvents such as water.

Interesting facts

Discovering N-ethyl-2-fluoro-N-(1-naphthyl)acetamide

N-ethyl-2-fluoro-N-(1-naphthyl)acetamide is a fascinating compound with intriguing properties and applications. Here are some interesting facts that highlight its significance in the field of chemistry:

  • Fluorine's Influence: The presence of fluorine in this compound enhances its biological activity, making it an area of interest in medicinal chemistry. Fluorinated compounds often exhibit improved pharmacokinetic properties.
  • Structural Complexity: This compound features a unique blend of a naphthyl group and an acetamide backbone. The naphthyl moiety contributes to its aromatic character, which can influence the compound's interactions and stability.
  • Research Applications: N-ethyl-2-fluoro-N-(1-naphthyl)acetamide is studied for its potential applications in drug discovery. Researchers are keen to explore its effects on various biological systems, aiming to develop novel therapeutics.
  • Synthetic Pathways: The synthesis of this compound involves intricate organic reactions. Its study provides valuable insights into **reactivity, selectivity**, and the **development of fluorinated pharmaceuticals**.
  • Environmental Considerations: As with all fluorinated compounds, understanding the environmental impact is crucial. Studying the degradation and persistence of such compounds can inform safer chemical design.

In summary, N-ethyl-2-fluoro-N-(1-naphthyl)acetamide serves as a great example of how small modifications in chemical structure can lead to significant changes in properties and applications. As scientists continue to explore this compound, it promises to yield valuable insights in both medicinal chemistry and organic synthesis.

Synonyms
10016-03-2
BRN 2125393
N-Ethyl-2-fluoro-N-1-naphthylacetamide
ACETAMIDE, N-ETHYL-2-FLUORO-N-1-NAPHTHYL-
DTXSID30142982
DTXCID1065473
N-ethyl-2-fluoro-N-naphthalen-1-ylacetamide
N-Ethyl-2-fluoro-N-(1-naphtyl)acetamide