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N-ethyl-2-fluoro-N-(1-naphthylmethyl)ethanamine

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Identification
Molecular formula
C15H18FN
CAS number
None
IUPAC name
N-ethyl-2-fluoro-N-(1-naphthylmethyl)ethanamine
State
State

At room temperature, N-ethyl-2-fluoro-N-(1-naphthylmethyl)ethanamine is in a liquid state. It has a low melting point indicating it may become solid at lower temperatures.

Melting point (Celsius)
-20.00
Melting point (Kelvin)
253.15
Boiling point (Celsius)
290.50
Boiling point (Kelvin)
563.65
General information
Molecular weight
241.31g/mol
Molar mass
241.3140g/mol
Density
1.1030g/cm3
Appearence

N-ethyl-2-fluoro-N-(1-naphthylmethyl)ethanamine typically appears as a liquid under standard conditions. Its exact appearance can vary, but it might have a clear, colorless to pale yellow hue. It does not have a defined crystalline appearance since it is not usually isolated in solid form.

Comment on solubility

Solubility of N-ethyl-2-fluoro-N-(1-naphthylmethyl)ethanamine

The solubility profile of N-ethyl-2-fluoro-N-(1-naphthylmethyl)ethanamine is influenced by several factors, primarily its molecular structure and interactions with different solvents.

  • Polarity: The presence of polar functional groups in the compound may contribute to its ability to dissolve in polar solvents, such as water, while its hydrophobic naphthyl group can lead to significant interactions with non-polar solvents.
  • Hydrogen bonding: Due to the nitrogen atom, there is potential for hydrogen bonding with the solvent, enhancing solubility in certain conditions.
  • Temperature: Increasing temperature typically enhances solubility for most organic compounds. Thus, heating the solvent before dissolution could yield better solubility results.
  • pH Influence: The solubility can vary significantly depending on the pH of the solution, particularly if the amino group can become protonated in acidic conditions.

It is essential to conduct experimental solubility testing to determine the specific solubility of N-ethyl-2-fluoro-N-(1-naphthylmethyl)ethanamine in diverse solvents.

In conclusion, the solubility of this compound is not solely dictated by one factor but rather a complex interplay of its structural characteristics and environmental conditions. Understanding these nuances is crucial for its practical applications in various fields.

Interesting facts

Interesting Facts About N-ethyl-2-fluoro-N-(1-naphthylmethyl)ethanamine

N-ethyl-2-fluoro-N-(1-naphthylmethyl)ethanamine is a unique compound that has drawn interest in various fields, particularly in medicinal chemistry and pharmacology. Here are some intriguing facts about this compound:

  • Fluorinated Compounds: The presence of fluorine in this compound can significantly influence its biological activity and pharmacokinetics. Fluorination often improves metabolic stability and lipophilicity, making it a common strategy in drug design.
  • Naphthyl Group: The inclusion of the naphthyl moiety adds to the compound’s aromaticity, which can enhance its interaction with biological targets, potentially impacting its efficacy.
  • Potential Applications: Compounds with similar structures have been investigated for their potential as antidepressants and psychoactive substances, making this particular compound of interest for further research.
  • Synthetic Pathways: Chemists utilize various methods to synthesize such compounds, often involving amination reactions that leverage the unique properties of ethyl and naphthyl groups for selective attachment.
  • Research Significance: Studying N-ethyl-2-fluoro-N-(1-naphthylmethyl)ethanamine can provide insights into the structure-activity relationships (SAR) that are crucial for developing new pharmaceuticals.

In summary, N-ethyl-2-fluoro-N-(1-naphthylmethyl)ethanamine exemplifies how structural modifications can lead to compounds with enhanced properties. Its *fluorinated* nature and complexities derived from the naphthyl ring provide promising avenues for both academic and applied research in drug development.

Synonyms
BRN 3282976
1-NAPHTHALENEMETHYLAMINE, N-ETHYL-N-(2-FLUOROETHYL)-
N-Ethyl-N-(2-fluoroethyl)naphthalene-1-methylamine
318-87-6
DTXSID60185665
DTXCID00108156