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Nitrofurazone

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Identification
Molecular formula
C8H7N3O4
CAS number
59-87-0
IUPAC name
N-ethyl-3-(5-nitro-2-furyl)prop-2-enamide
State
State

At room temperature, nitrofurazone is in a solid state. It exists as a stable crystalline powder under standard conditions of temperature and pressure. Nitrofurazone does not readily liquefy at room temperature unless dissolved in a suitable solvent.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
333.00
Boiling point (Kelvin)
606.15
General information
Molecular weight
198.16g/mol
Molar mass
198.1570g/mol
Density
1.3670g/cm3
Appearence

Nitrofurazone typically appears as a yellow, crystalline powder. It has a distinctive yellow hue, which is quite characteristic of many nitro-containing aromatic compounds. The powder is fine and can be challenging to handle due to its light, fluffy nature, sometimes clumping slightly due to static or minor moisture absorption.

Comment on solubility

Solubility of N-ethyl-3-(5-nitro-2-furyl)prop-2-enamide

N-ethyl-3-(5-nitro-2-furyl)prop-2-enamide exhibits intriguing solubility characteristics, primarily influenced by its chemical structure and the presence of functional groups. Understanding its solubility can be broken down as follows:

  • Polarity: The electron-withdrawing nitro group and the amide functional group enhance the polarity of this compound, suggesting that it may have a better solubility in polar solvents such as water and alcohols.
  • Hydrogen Bonding: The amide group can participate in hydrogen bonding, which can further facilitate solubility in polar solvents while possibly limiting solubility in non-polar solvents.
  • Temperature Dependence: Like many organic compounds, the solubility of N-ethyl-3-(5-nitro-2-furyl)prop-2-enamide can be affected by temperature; typically, increased temperatures can enhance solubility.
  • Miscibility: This compound may show various degrees of miscibility with common organic solvents, which can be critical in practical applications.

In summary, *N-ethyl-3-(5-nitro-2-furyl)prop-2-enamide* stands out with its potential to dissolve effectively in polar environments, thanks to both its structural features and the nature of its intermolecular interactions. As with all compounds, the assessment of solubility is essential for understanding its reactivity and applications in various chemical contexts.

Interesting facts

Interesting Facts about N-ethyl-3-(5-nitro-2-furyl)prop-2-enamide

N-ethyl-3-(5-nitro-2-furyl)prop-2-enamide is a fascinating compound with intriguing properties and applications. As a member of the amide family, it features unique structural characteristics that contribute to its chemical behavior and potential uses. Here are some noteworthy facts about this compound:

  • Nitro Functional Group: The presence of a nitro group (-NO2) on the furan ring enhances the reactivity of the compound, making it an interesting target for various chemical reactions.
  • Furan Derivative: The furan component of the molecule is a five-membered aromatic ring. These types of compounds are known for their interesting biological activity and can serve as precursors in organic synthesis.
  • Potential Pharmacological Properties: Compounds with similar structures have been studied for their potential pharmacological effects, including anti-inflammatory and antitumor activities. The nitro substituent might play a significant role in enhancing these activities.
  • Environmental Considerations: As with many nitro-containing compounds, it is vital to study their environmental impact, especially regarding their degradation and interaction with biological systems. Understanding these interactions can inform safety protocols for both laboratory and industrial use.

This compound exemplifies how small variations in chemical structure can lead to substantial differences in properties and functionality. As chemists explore N-ethyl-3-(5-nitro-2-furyl)prop-2-enamide, they contribute to the broader understanding of amide derivatives and their potential roles in various scientific fields.