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N-ethyl-4-nitroaniline

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Identification
Molecular formula
C8H10N2O2
CAS number
3426-07-1
IUPAC name
N-ethyl-4-nitro-aniline
State
State

At room temperature, N-ethyl-4-nitroaniline is in a solid state. It is often handled as a solid due to its relatively high melting point.

Melting point (Celsius)
60.00
Melting point (Kelvin)
333.15
Boiling point (Celsius)
325.00
Boiling point (Kelvin)
598.15
General information
Molecular weight
180.19g/mol
Molar mass
180.1950g/mol
Density
1.2160g/cm3
Appearence

N-ethyl-4-nitroaniline is a yellow crystalline solid. Crystals are typically needle-like or granular in texture. It has a distinct yellow hue due to the presence of the nitro group, which can cause noticeable coloring.

Comment on solubility

Solubility of N-ethyl-4-nitro-aniline

N-ethyl-4-nitro-aniline, with the chemical formula C8H10N2O2, exhibits interesting solubility characteristics that are influenced by its structural components. Due to the presence of an amino group and a nitro group, this compound shows varying degrees of solubility in different solvents:

  • Polar Solvents: N-ethyl-4-nitro-aniline is soluble in polar solvents such as water, methanol, and ethanol. The amino group can hydrogen bond with water, enhancing solubility.
  • Non-Polar Solvents: It has limited solubility in non-polar solvents like hexane or benzene, which can affect its applications in certain chemical processes.
  • Influence of Temperature: The solubility can increase with temperature, making it easier to dissolve the compound at higher temperatures.
  • pH Dependence: The pH of the solution can also play a crucial role; the ionization state of the amino group may change with pH, affecting its solubility.

In summary, N-ethyl-4-nitro-aniline's solubility profile highlights it as a versatile compound in synthetic chemistry. Understanding its solubility behavior is essential for its effective application in various fields.

Interesting facts

N-ethyl-4-nitro-aniline

N-ethyl-4-nitro-aniline, an organic compound, is an important derivative of aniline, categorized as an aromatic amine. This compound features a nitro group and an ethyl substituent, making it unique in its properties and applications.

Key Properties and Applications

  • Dye Industry: N-ethyl-4-nitro-aniline plays a significant role as a precursor in the synthesis of azo dyes, which are extensively used in textiles.
  • Pharmaceuticals: Some derivatives of this compound have been studied for their potential medicinal properties, including anti-cancer activities.
  • Research Reagent: It serves as an important reagent in organic synthesis and various chemical reactions, allowing researchers to explore new pathways in organic chemistry.

Health and Safety Considerations

While N-ethyl-4-nitro-aniline has valuable applications, proper safety measures should be taken when handling it due to its potential toxicity. Experts often emphasize the importance of using protective gear to minimize exposure. In fact, many safety data sheets (SDS) highlight that:

  • It may cause skin irritation and is harmful if inhaled.
  • Long-term exposure could pose serious health risks, thereby necessitating proper disposal methods.

Interesting Tidbit

Due to the presence of the nitro group, this compound showcases interesting reactivity patterns that can be exploited in chemical synthesis. The research community often notes the versatility of nitro-substituted compounds, as they can undergo various transformations, leading to a broad spectrum of chemical products.

Overall, N-ethyl-4-nitro-aniline serves not just as a compound of theoretical interest, but also as a practical material that bridges various fields of chemistry—from industrial applications to fundamental research.

Synonyms
N-Ethyl-4-nitroaniline
N-Ethyl-p-nitroaniline
Benzenamine, N-ethyl-4-nitro-
N-ETHYL-4-NITROBENZENAMINE
HIJ38TTD80
EINECS 222-927-1
UNII-HIJ38TTD80
DTXSID3063124
ETHYL-4-NITROANILINE, N-
ANILINE, N-ETHYL-P-NITRO-
DTXCID6039213
222-927-1
inchi=1/c8h10n2o2/c1-2-9-7-3-5-8(6-4-7)10(11)12/h3-6,9h,2h2,1h
xbnnlawqcmdisj-uhfffaoysa-n
3665-80-3
N-Ethyl-N-(4-nitrophenyl)amine
N-Ethyl-4-nitro-benzenamine
MFCD00010647
CDS1_000053
N-ethyl 4-nitroaniline
p-nitrophenyl-ethylamine
4-nitrophenyl-ethylamine
Maybridge1_002341
N1-ethyl-4-nitroaniline
aniline, N-ethyl-4-nitro-
MLS000851160
DivK1c_001093
SCHEMBL570831
ethyl-(4-nitro-phenyl)-amine
N-Ethyl-4-nitroaniline, 99%
CHEMBL1378281
HMS548C09
HMS2777B10
DAA66580
N-Ethyl-N-(4-nitrophenyl)amine #
STL069463
AKOS004896753
NCGC00246665-01
AS-76339
SMR000457403
DB-048986
CS-0258169
NS00030073
EN300-69278
E85396
AE-562/43447810