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Tacrine

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Identification
Molecular formula
C13H14N2
CAS number
321-64-2
IUPAC name
N-ethyl-5,6,7,8-tetrahydroacridin-1-amine
State
State

Tacrine is in a solid state at room temperature.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
542.20
Boiling point (Kelvin)
815.40
General information
Molecular weight
198.27g/mol
Molar mass
198.2710g/mol
Density
1.3000g/cm3
Appearence

Tacrine typically appears as an off-white to pale yellow crystalline powder.

Comment on solubility

Solubility of N-ethyl-5,6,7,8-tetrahydroacridin-1-amine

N-ethyl-5,6,7,8-tetrahydroacridin-1-amine exhibits interesting solubility characteristics that are worth discussing. Understanding the solubility behavior of this compound can help predict its application in various fields, particularly in pharmaceuticals and organic synthesis. Here are some key points regarding its solubility:

  • Polar & Non-Polar Solvents: This compound is likely to show solubility in polar solvents due to the presence of the nitrogen atom within its structure, which can engage in hydrogen bonding. However, it may also display some level of solubility in non-polar solvents due to its hydrophilic and hydrophobic balance.
  • Temperature Influence: As with many organic compounds, the solubility of N-ethyl-5,6,7,8-tetrahydroacridin-1-amine can be influenced by temperature. Generally, an increase in temperature can lead to greater solubility in many solutions.
  • pH Effects: The solubility can also be affected by the pH of the solution. In acidic conditions, the amine group may become protonated, increasing solubility in aqueous solutions.
  • Concentration Considerations: At elevated concentrations, this compound may reach saturation limits that affect its solubility dynamics.

Overall, the solubility of N-ethyl-5,6,7,8-tetrahydroacridin-1-amine is an important factor that can influence its reactivity, biological interactions, and usage in various applications. As with many amine-containing compounds, understanding these solubility traits can provide insight into how to effectively utilize this intriguing molecule.

Interesting facts

Interesting Facts about N-ethyl-5,6,7,8-tetrahydroacridin-1-amine

N-ethyl-5,6,7,8-tetrahydroacridin-1-amine is a fascinating compound that captures the attention of chemists and researchers alike. Here are some intriguing aspects of this compound:

  • Structural Features: This compound belongs to the acridine family, which is known for its unique fused-ring structure. The tetrahydro modification contributes to its chemical properties, making it an interesting subject for study.
  • Biological Significance: Compounds like N-ethyl-5,6,7,8-tetrahydroacridin-1-amine are often researched for their potential biological activities, including neuroprotective effects and anti-Alzheimer properties. This makes it a candidate for further pharmacological investigations.
  • Synthetic Pathways: The synthesis of this compound often involves innovative organic reactions, which can provide insight into reaction mechanisms and stereochemistry. These processes can be a great learning opportunity for students in organic chemistry.
  • Applications in Research: Due to its structural similarities to other bioactive molecules, it serves as a lead compound in drug development research. Scientists aim to modify its structure to enhance its efficacy and minimize side effects.
  • Intellectual Curiosity: The study of N-ethyl-5,6,7,8-tetrahydroacridin-1-amine opens avenues for discussions about molecular interactions, drug design, and therapeutic potentials, making it a stimulating topic in both academic and professional spheres.

Chemistry students often find the exploration of such compounds both challenging and rewarding, as they combine knowledge of organic synthesis, biological implications, and the potential for real-world applications.

In the words of a prominent chemist: "The beauty of chemistry lies not in the answers we find, but in the questions we dare to explore."

Synonyms
9-ACRIDINAMINE, 1,2,3,4-TETRAHYDRO-N-ETHYL-
958778-07-9
N-ethyl-5,6,7,8-tetrahydroacridin-1-amine
316-86-9
BRN 0479230
1,2,3,4-Tetrahydro-N-ethyl-9-acridinamine
DTXSID20185489