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N-ethylacetamide

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Identification
Molecular formula
C4H9NO
CAS number
625-50-3
IUPAC name
N-ethylacetamide
State
State

At room temperature, N-Ethylacetamide is a liquid.

Melting point (Celsius)
-86.00
Melting point (Kelvin)
187.00
Boiling point (Celsius)
215.70
Boiling point (Kelvin)
488.90
General information
Molecular weight
87.12g/mol
Molar mass
87.1210g/mol
Density
0.9120g/cm3
Appearence

N-Ethylacetamide is typically a colorless to pale yellow liquid. It possesses a slight, amine-like odor.

Comment on solubility

Solubility of N-ethylacetamide

N-ethylacetamide, with the chemical formula C4H9N1 O1, is a compound that exhibits notable solubility properties. Understanding the solubility of N-ethylacetamide can provide insight into its potential applications as a solvent and in chemical processes.

Key Solubility Characteristics:

  • Polarity: Being an amide, N-ethylacetamide is polar due to the presence of the carbonyl group (C=O), which enhances its ability to interact with polar solvents.
  • Solvent Compatibility: N-ethylacetamide is soluble in water, indicating its amphipathic nature, which enables it to dissolve well in aqueous environments. It also shows solubility in a variety of organic solvents such as alcohols and acetone.
  • Aufbau Principle: The presence of a polar C-N bond along with the hydrophilic carbonyl group contributes to its good solubility in polar solvents.

In summary, the solubility of N-ethylacetamide in various solvents is a crucial factor that can influence its use in chemical reactions and formulations. As stated in many studies, "The solubility behavior of amides is significantly affected by their molecular structure," which in the case of N-ethylacetamide showcases its versatility and compatibility with both polar and non-polar media.

Interesting facts

Interesting Facts about N-ethylacetamide

N-ethylacetamide is a fascinating compound known for its diverse applications in both industrial and laboratory settings. Here are some intriguing aspects of this lesser-known amide:

  • Versatile Solvent: N-ethylacetamide serves as an effective solvent for a variety of chemical reactions and processes. Its ability to dissolve both polar and non-polar substances makes it an invaluable resource in organic synthesis.
  • Biochemical Relevance: This compound is often used as a building block in the synthesis of pharmaceuticals and agrochemicals. Its role in medicinal chemistry emphasizes its importance in the development of new drug candidates.
  • Safety and Handling: While working with N-ethylacetamide, it’s crucial to observe appropriate safety protocols. It is recommended to use personal protective equipment (PPE) to minimize exposure, as with many organic solvents.
  • Thermal Stability: N-ethylacetamide exhibits a good degree of thermal stability, allowing it to be utilized in reactions that require elevated temperatures without significant degradation.

As a compound, N-ethylacetamide illustrates the interplay between organic chemistry and real-world applications. Its unique structure, which consists of an ethyl group attached to an acetamide functional group, is key to its functionality. Understanding and exploring compounds like N-ethylacetamide contributes to advancements in chemical research and development.

In the words of a notable chemist, "The beauty of chemistry lies in its ability to transform simple molecules into complex structures with profound implications." This sentiment is perfectly captured by the versatility of N-ethylacetamide in various fields.

Synonyms
N-ETHYLACETAMIDE
Acetamide, N-ethyl-
Acetamidoethane
Ethylacetamide
Acetoethylamide
N-Acetylethylamine
N-Aethylacetamid
N-Aethylacetamid [German]
EINECS 210-896-7
NSC 406307
BRN 0969292
M9Y95ZE6J9
AI3-02181
ETHYLACETAMIDE, N-
NSC-406307
UNII-M9Y95ZE6J9
DTXSID5060803
CHEBI:87370
4-04-00-00347 (Beilstein Handbook Reference)
NAethylacetamid
Acetamide, Nethyl
DTXCID7043370
210-896-7
inchi=1/c4h9no/c1-3-5-4(2)6/h3h2,1-2h3,(h,5,6
pmdczencaxmsou-uhfffaoysa-n
625-50-3
N-Ethyl-acetamide
MFCD00009029
N-ethylethanamide
N-Ethylacetamide, 99%
WLN: 2MV1
AC2513
NSC406307
AKOS003857793
CS-W011352
SY016499
DB-054195
E0324
NS00035066
C21404
Q27159564