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N-Ethylformamide

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Identification
Molecular formula
C3H7NO
CAS number
627-45-2
IUPAC name
N-ethylformamide
State
State

N-Ethylformamide is a liquid at room temperature.

Melting point (Celsius)
-93.00
Melting point (Kelvin)
180.15
Boiling point (Celsius)
181.80
Boiling point (Kelvin)
454.95
General information
Molecular weight
73.09g/mol
Molar mass
73.0940g/mol
Density
0.9481g/cm3
Appearence

N-Ethylformamide is a colorless liquid.

Comment on solubility

Solubility of N-ethylformamide

N-ethylformamide, with the chemical formula C3H7NO, exhibits notable solubility characteristics due to its molecular structure. This compound is typically considered:

  • Highly soluble in polar solvents: N-ethylformamide easily dissolves in water and other polar solvents like alcohols.
  • Moderately soluble in non-polar solvents: While it shows some solubility in organic non-polar solvents, the extent is significantly less compared to its solubility in polar environments.
  • Influenced by temperature: Like many substances, solubility can increase with temperature; thus, warm conditions often enhance its dissolution in various solvents.

The ability of N-ethylformamide to form hydrogen bonds due to its amide functional group enhances its solubility profile, making it a valuable compound in various chemical reactions and applications. As one might say, "A compound's utility often depends on its solubility," highlighting the importance of understanding this aspect in both academic and industrial settings.

Interesting facts

Interesting Facts about N-ethylformamide

N-ethylformamide is a fascinating chemical compound that falls within the realm of amides, which are derivatives of carboxylic acids. This particular compound is notable for its unique structure and various applications:

  • Structural Characteristics: N-ethylformamide features an ethyl group connected to the nitrogen atom of the formamide functional group. This structure plays a crucial role in its chemical reactivity and interactions.
  • Synthesis: It can be synthesized through the reaction of ethylamine with formic acid, showcasing a beautiful example of organic synthesis. The process highlights the importance of amine acids in producing specific functional groups.
  • Applications: N-ethylformamide has valuable applications in both industrial and research settings. It is often used as a solvent and an intermediate in the production of pharmaceuticals, agricultural chemicals, and polymeric substances.
  • Biological Significance: Due to its amide nature, N-ethylformamide can interact with biological molecules and may contribute to various biochemical processes. Its potential role in the formulation of drug compounds makes it of particular interest to medicinal chemists.
  • Safety Considerations: Handling N-ethylformamide requires understanding basic safety protocols. The compound can be harmful if ingested or improperly handled, emphasizing the need for a solid foundation in chemical safety.

As a compound that bridges the gap between organic chemistry and practical application, N-ethylformamide showcases the intricate world of chemical synthesis. Exploring its properties and effects can lead to exciting discoveries in many fields.

Synonyms
N-Ethylformamide
Formamide, N-ethyl-
N-FORMYLETHYLAMINE
Ethylformamide
N-Aethylformamid
N-Aethylformamid [German]
ethylaminocarbonyl
VJF7XCH5B6
EINECS 211-001-2
NSC 404522
BRN 1737860
AI3-18804
UNII-VJF7XCH5B6
NSC-404522
DTXSID6060842
DTXCID0043501
211-001-2
4-04-00-00346 (beilstein handbook reference)
kerbaaibdhefdd-uhfffaoysa-n
627-45-2
N-ethyl formamide
N-Ethyl-formamide
NSC404522
CHEMBL9421
MFCD00042672
AKOS009156775
N-Ethylformamide, >=99.0% (GC)
DB-321113
CS-0187584
F0188
NS00035158
F19558