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N-(Fluoro-(isopropylamino)phosphoryl)propan-2-amine

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Identification
Molecular formula
C6H16FN2OP
CAS number
1333-83-5
IUPAC name
N-[fluoro-(isopropylamino)phosphoryl]propan-2-amine
State
State

At room temperature, the compound is in a liquid state.

Melting point (Celsius)
-50.00
Melting point (Kelvin)
223.15
Boiling point (Celsius)
103.00
Boiling point (Kelvin)
376.15
General information
Molecular weight
161.12g/mol
Molar mass
161.1000g/mol
Density
1.2000g/cm3
Appearence

The compound is usually found as a colorless or slightly yellow liquid, displaying a clear appearance.

Comment on solubility

Solubility of N-[fluoro-(isopropylamino)phosphoryl]propan-2-amine

N-[fluoro-(isopropylamino)phosphoryl]propan-2-amine, with its complex molecular structure, presents fascinating characteristics in terms of solubility. The solubility of this compound can be influenced by several key factors:

  • Polarity: The presence of fluorine and an amine group often enhances the polarity of the molecule, potentially improving its solubility in polar solvents.
  • Hydrogen Bonding: The amine functionality may engage in hydrogen bonding interactions with water, suggesting a likelihood of soluble behavior in aqueous environments.
  • Log P Value: A quantitative measure such as the partition coefficient (Log P) can help predict solubility in both aqueous and organic solvents; lower values generally indicate a higher likelihood of solubility in water.
  • Temperature: Solubility may vary significantly with temperature; thus, elevated temperatures could lead to increased solubility.

In summary, while definitive solubility data may not be readily available, it is reasonable to hypothesize that N-[fluoro-(isopropylamino)phosphoryl]propan-2-amine exhibits moderate solubility characteristics in polar solvents due to its polar functional groups and potential hydrogen-bonding capacity. To accurately assess its solubility, experimental testing under controlled conditions would be recommended.

Interesting facts

Interesting Facts about N-[fluoro-(isopropylamino)phosphoryl]propan-2-amine

N-[fluoro-(isopropylamino)phosphoryl]propan-2-amine is a notable compound in the realm of organic chemistry, particularly in the field of medicinal chemistry. This compound features a unique combination of elements that contribute to its interesting properties and potential applications.

Key Characteristics

  • Phosphorus-Containing Compound: The presence of phosphorus in its structure indicates its potential use in biochemical applications, especially in the synthesis of organophosphorus compounds.
  • Fluorine Atom: The fluorine atom in the compound can significantly enhance its pharmacological properties, making it an intriguing subject for drug design.
  • Amine Functionality: With its amine group, this compound may exhibit basic properties and can interact with various biological systems, leading to diverse functions.

Potential Applications

This compound could be explored for several important applications:

  • Pest Control: Similar phosphorus compounds are often used in agrochemicals, suggesting potential uses in pesticide formulations.
  • Pharmaceutical Development: Due to its structural diversity, it might be synthesized in derivatives that could serve as therapeutic agents or intermediates.
  • Biochemical Research: The complex nature of the compound may enable it to act as a probe or marker in biological studies.

Research Implications

As scientists delve deeper into its properties, they might uncover novel interactions or mechanisms related to:

  • Medicinal chemistry
  • Synergistic effects in pharmacology
  • Environmental chemistry through its potential impact in ecosystems

In conclusion, N-[fluoro-(isopropylamino)phosphoryl]propan-2-amine represents an exciting molecule with promising significance across various fields. Its multifaceted characteristics warrant continued exploration, and as famed chemist Linus Pauling once said, “The best way to have a good idea is to have lots of ideas.” Indeed, this compound may inspire many innovative thoughts in the chemical sciences.

Synonyms
MIPAFOX
371-86-8
Isopestox
N,N'-Diisopropylphosphorodiamidic fluoride
Peston XV
Pestox XV
Pestox 15
Mipafox [ISO]
Bis(isopropylamido) fluorophosphate
Caswell No. 356B
Bis(monoisopropylamino)fluorophosphate
Di(isopropylamido)phosphoryl fluoride
Phosphorodi(isopropylamidic) fluoride
N,N'-Diisopropyldiamidophosphoryl fluoride
NSC 8924
Bis(monoisopropylamino)fluorophosphine oxide
Bisisopropylaminofluorophosphine oxide
Phosphine oxide, fluorobis(isopropylamino)-
HSDB 1585
Bis(isopropylamido)fluorophosphate
N,N'-Diisopropil-fosforodiammido-fluoruro
UNII-24MJP5H3YN
N,N'-Diisopropyl-diamido-fosforzuur-fluoride
Phosphorodiamidic fluoride, N,N'-bis(1-methylethyl)-
EINECS 206-742-3
Fluorobisisopropylaminophosphine oxide
24MJP5H3YN
Phosphorodiamidic fluoride, N,N'-diisopropyl-
Fluorure de N,N'-diisopropyle phosphorodiamide
N,N'-Diisopropyl-diamido-phosphorsaeure-fluorid
EPA Pesticide Chemical Code 356300
BRN 1705911
N-[fluoro-(propan-2-ylamino)phosphoryl]propan-2-amine
MIPAFOX [HSDB]
NSC-8924
MIPAFOX [MI]
N,N'-Diisopropil-fosforodiammido-fluoruro [Italian]
N,N'-Diisopropyl-diamido-fosforzuur-fluoride [Dutch]
UN 2783 (Salt/Mix)
Fluorure de N,N'-diisopropyle phosphorodiamide [French]
N,N'-Diisoprophyl phosphordiamide fluoride
N,N'-Diisopropyl-diamido-phosphorsaeure-fluorid [German]
DTXSID5042160
4-04-00-00536 (Beilstein Handbook Reference)
N,N'-BIS(1-METHYLETHYL)PHOSPHORODIAMIDIC FLUORIDE
Fluoro(bis(isopropylamino))phosphine oxide
bis[(propan-2-yl)amino]phosphinoyl fluoride
Fluoro[bis(isopropylamino)]phosphine oxide
N,N'-DIISOPROPIL-FOSFORODIAMMIDO-FLUORURO (ITALIAN)
N,N'-DIISOPROPYL-DIAMIDO-PHOSPHORSAEURE-FLUORID (GERMAN)
N,N'-di-isopropylphosphorodiamidic fluoride
SCHEMBL119253
DTXCID3022160
CHEBI:82142
NSC8924
WLN: 1Y1&MPO&FMY1&1
ALBB-027255
STL388019
N,N'Diisopropilfosforodiammidofluoruro
AKOS017258617
N,N'Diisopropyldiamidofosforzuurfluoride
USEPA/OPP Pesticide Code: 356300
N,N'Diisopropyldiamidophosphoryl fluoride
N,N'Diisopropylphosphorodiamidic fluoride
Phosphine oxide, fluorobis(isopropylamino)
N,N'Diisopropyldiamidophosphorsaeurefluorid
Phosphorodiamidic fluoride,N'-diisopropyl-
DI(ISOPROPYLAMIDO) PHOSPHORYLFLUORIDE
Phosphorodiamidic fluoride, N,N'diisopropyl
Fluorure de N,N'diisopropyle phosphorodiamide
N,N'- Di-isopropylphosphorodiamidic fluoride
N,N'-dipropan-2-ylphosphorodiamidic fluoride
NS00030168
BIS(ISOPROPYLAMINO)FLUOROPHOSPHINE OXIDE
C19008
EN300-266699
G40368
Phosphorodiamidic fluoride, N,N'bis(1methylethyl)
Phosphorodiamidic fluoride,N'-bis(1-methylethyl)-
N,N'-bis(1-methylethyl)-phosphorodiamidic fluoride
N,N'-diisopropyl-phosphorodiamidic fluoride, mipafox
N,N(-DIISOPROPYL-DIAMIDO-FOSFORZUUR-FLUORIDE
Q26841312
Z1681338465
N,N(-DIISOPROPYL-DIAMIDO-FOSFORZUUR-FLUORIDE (DUTCH)
Phosphorodiamidic fluoride, N,N'-bis(1-methylethyl)-(9CI)
206-742-3