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N'-hydroxy-2-indol-1-yl-acetamidine

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Identification
Molecular formula
C10H11N3O
CAS number
883030-27-3
IUPAC name
N'-hydroxy-2-indol-1-yl-acetamidine
State
State

At room temperature, N'-hydroxy-2-indol-1-yl-acetamidine is a solid.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
187.21g/mol
Molar mass
187.2070g/mol
Density
1.2345g/cm3
Appearence

N'-hydroxy-2-indol-1-yl-acetamidine typically appears as a crystalline solid. It may be off-white to light yellow in color depending on purity and the specific conditions under which it is observed. It is often synthesized for research purposes.

Comment on solubility

Solubility of N'-hydroxy-2-indol-1-yl-acetamidine

N'-hydroxy-2-indol-1-yl-acetamidine exhibits particular solubility characteristics that merit attention. Understanding its solubility can aid in its applications in various fields such as pharmaceuticals and organic synthesis.

General Solubility Characteristics

The solubility of N'-hydroxy-2-indol-1-yl-acetamidine can be influenced by several factors:

  • Polarity: As a compound featuring both hydroxy and amidine functional groups, it possesses polar characteristics, suggesting it may dissolve in polar solvents.
  • pH Sensitivity: The presence of an amidine group can lead to changes in solubility based on pH levels, highlighting that its solubility can vary in acidic versus basic conditions.
  • Temperature Dependence: Like many organic compounds, increased temperature may enhance solubility due to greater molecular motion.

In general, compounds that include amino and hydroxyl groups tend to have increased solubility in water. Therefore, N'-hydroxy-2-indol-1-yl-acetamidine might dissolve well in aqueous solutions, especially if the solution is adjusted to an appropriate pH.

Considerations for Practical Applications

When utilizing N'-hydroxy-2-indol-1-yl-acetamidine in laboratory settings, keep in mind:

  • Always test solubility in a variety of solvents, including water, ethanol, and dimethyl sulfoxide (DMSO).
  • Monitor the compound's behavior under different temperature conditions to determine the right conditions for its use or synthesis.

Ultimately, understanding the solubility of N'-hydroxy-2-indol-1-yl-acetamidine is crucial for harnessing its potential effectively. By comprehensively evaluating its solubility in various environments, researchers can optimize its applications and enhance its utility.

Interesting facts

Interesting Facts About N'-hydroxy-2-indol-1-yl-acetamidine

N'-hydroxy-2-indol-1-yl-acetamidine is a fascinating compound that plays an intriguing role in the field of medicinal chemistry and biochemistry. Here are some key points to consider:

  • Biological Significance: This compound is often studied for its potential applications in drug development, particularly for its activity against various biological targets.
  • Indole Structure: The indole structure, which consists of a fused benzene and pyrrole ring, is a common motif in many natural products and pharmaceuticals, enhancing the compound's relevance.
  • Mechanisms of Action: Research has indicated that compounds with indole derivatives can influence various mechanisms in biological pathways, making N'-hydroxy-2-indol-1-yl-acetamidine an interesting candidate for exploration in pharmacological contexts.
  • Potential Therapeutic Applications: While research is ongoing, there is promise that compounds similar to N'-hydroxy-2-indol-1-yl-acetamidine could lead to the development of novel therapeutic agents.
  • Research Interest: Chemists and biochemists are keenly interested in synthesizing derivatives of this compound to enhance its efficacy or reduce potential side effects.

As scientists delve deeper into both its structure and function, the implications of N'-hydroxy-2-indol-1-yl-acetamidine could extend far beyond our current understanding, leading to breakthroughs in various fields of science.

Quote to ponder: "The most exciting discoveries are often found at the intersection of organic chemistry and biology."

Synonyms
INDOLE-1-ACETAMIDOXIME