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Tazobactam

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Identification
Molecular formula
C10H12N4O5S
CAS number
89786-04-9
IUPAC name
[N-hydroxy-C-[[o-tolyl(phenyl)methoxy]methyl]carbonimidoyl]ammonium;4-hydroxy-4-oxo-but-2-enoate
State
State
At room temperature, Tazobactam is in a solid state and it is commonly used in conjunction with other antibiotics to enhance their efficacy.
Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
453.15
Boiling point (Kelvin)
726.30
General information
Molecular weight
300.31g/mol
Molar mass
300.3070g/mol
Density
1.3400g/cm3
Appearence

Tazobactam is typically observed as a white to off-white crystalline powder. It is stable under normal temperatures and pressures, making it suitable for pharmaceutical formulations.

Comment on solubility

Solubility of N-hydroxy-C-[[o-tolyl(phenyl)methoxy]methyl]carbonimidoyl]ammonium;4-hydroxy-4-oxo-but-2-enoate

The solubility of this compound is an intriguing aspect to delve into, as it encompasses two distinct components that may exhibit different characteristics in various solvents.

Factors Influencing Solubility

When examining the solubility of this compound, several key factors come into play:

  • Molecular Structure: The presence of functional groups, such as hydroxyl and carbonimidoyl moieties, can significantly enhance solubility in polar solvents due to their ability to form hydrogen bonds.
  • Hydrophobic Interactions: The incorporation of the o-tolyl and phenyl groups suggests that portions of the molecule may exhibit hydrophobic characteristics, which might lead to limited solubility in aqueous solutions.
  • pH of the Solution: The solubility could also be affected by the pH level, particularly since the compound contains ammonium, which can change its protonation state in different pH environments.

Expected Solubility

Given these factors, one can anticipate the following:

  • In polar solvents like water, the solubility may be moderate due to the competing hydrophilic and hydrophobic regions.
  • In organic solvents such as ethanol or methanol, the solubility could be enhanced due to the more compatible interactions with the hydrophobic functionality.
  • Conversely, non-polar solvents might exhibit low solubility levels, reflecting the adverse interactions of the hydrophilic sites.

In conclusion, understanding the solubility of N-hydroxy-C-[[o-tolyl(phenyl)methoxy]methyl]carbonimidoyl]ammonium;4-hydroxy-4-oxo-but-2-enoate requires careful consideration of its structural attributes and the solvent environment, making it a complex yet fascinating study in the realm of chemical compounds.

Interesting facts

Interesting Facts About N-hydroxy-C-[[o-tolyl(phenyl)methoxy]methyl]carbonimidoyl]ammonium;4-hydroxy-4-oxo-but-2-enoate

This compound exhibits a fascinating structure that merges the principles of organic and medicinal chemistry. Its unique arrangement creates pathways for various interactions, making it a subject of interest in numerous chemical studies.

Key Features:

  • Hybrid Nature: The compound incorporates both hydroxy and imidoyl functional groups, showcasing versatility in chemical reactivity.
  • Biological Applications: Compounds with similar structures are often explored for their potential as bioactive agents in pharmaceuticals, especially in anti-inflammatory and anticancer research.
  • Synthetic Routes: Its complex synthetic pathway can involve multiple steps, making it a great example for students learning about organic synthesis methodologies.
  • Structure-Activity Relationship (SAR): Understanding how structural changes influence the compound's biological activity can lead to the design of more effective therapeutics.

As a characteristic blend of functional groups, the study of this compound can also provide insights into mechanistic pathways of reactions in organic chemistry. The incorporation of tolyl and phenyl groups enhances its stability and offers intrigue into its reactivity patterns.

In the words of a prominent chemist, “Complex structures provide complex answers.” This compound is a prime example of how intricate chemistry can lead to new discoveries and innovations in various fields.