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N-Hydroxy-N-(4-phenylphenyl)acetamide

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Identification
Molecular formula
C14H13NO2
CAS number
21499-56-5
IUPAC name
N-hydroxy-N-(4-phenylphenyl)acetamide
State
State
This compound is a solid at room temperature, typically presented as a crystalline powder.
Melting point (Celsius)
129.00
Melting point (Kelvin)
402.15
Boiling point (Celsius)
352.12
Boiling point (Kelvin)
625.27
General information
Molecular weight
227.27g/mol
Molar mass
227.2680g/mol
Density
1.2487g/cm3
Appearence

This compound typically appears as a white to off-white powder. It has a crystalline structure and is usually odorless.

Comment on solubility

Solubility of N-hydroxy-N-(4-phenylphenyl)acetamide

N-hydroxy-N-(4-phenylphenyl)acetamide, a compound with intriguing properties, exhibits solubility behavior that can be quite noteworthy. The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of the hydroxy group enhances polarity, which can improve solubility in polar solvents such as water.
  • Solvent Selection: It is likely to be more soluble in organic solvents such as ethanol or acetone due to its organic nature.
  • Temperature: As with many organic compounds, solubility may increase with temperature, allowing for better dissolution in heated solvents.
  • pH Level: The solubility may also exhibit pH-dependent behavior, particularly if the compound is ionizable at certain pH levels.

In practical terms, it is often observed that:

  1. The compound is likely to be moderately soluble in common organic solvents.
  2. Limited solubility in water can occur, but certain formulation techniques may enhance its dissolution.

Understanding the solubility characteristics of N-hydroxy-N-(4-phenylphenyl)acetamide is essential for its application in various fields, including pharmaceuticals and material sciences, and it opens avenues for its use in formulation strategies.

Interesting facts

Interesting Facts about N-hydroxy-N-(4-phenylphenyl)acetamide

N-hydroxy-N-(4-phenylphenyl)acetamide is a fascinating chemical compound with a variety of intriguing characteristics. As a derivative of acetamide, it showcases some key features that make it worthy of exploration:

  • Structure and Composition: The compound comprises a hydroxy group attached to an acetamide backbone, with a phenyl group on either side, enhancing its molecular complexity and functional capabilities.
  • Biological Significance: Compounds similar to N-hydroxy-N-(4-phenylphenyl)acetamide have been studied for their potential biological activities, including anti-inflammatory and analgesic properties, which highlights their importance in medicinal chemistry.
  • Synthetic Pathways: The synthesis of this compound often involves the reactions between phenyl derivatives and acetylating agents, making it an interesting subject of study in organic synthesis courses.
  • Applications: Beyond its biological significance, this compound can serve as an intermediate in the synthesis of more complex pharmaceuticals and materials, illustrating its versatility in chemical applications.
  • A Center for Research: Researchers are continuously investigating derivatives of this compound to enrich our understanding of structure-activity relationships in pharmacology, enriching the field of drug design.

“Chemistry is the mother of all sciences, and each compound tells its unique story.”

Overall, N-hydroxy-N-(4-phenylphenyl)acetamide stands as a noteworthy compound in the world of chemistry, with potentials that beckon further study and exploration.

Synonyms
N-Hydroxy-4-acetylaminobiphenyl
4463-22-3
N-Hydroxy-4-acetamidodiphenyl
N-Hydroxy-aabp
N-Hydroxy-N-4-biphenylacetamide
4-Biphenylacethydroxamic acid
N-Hydroxy-4-acetamidobiphenyl
N-Acetyl-4-biphenylhydroxylamine
N-4-Biphenylylacetohydroxamic acid
N-4-(N-Hydroxyacetamido)biphenyl
N-Acetyl-N-hydroxy-4-aminobiphenyl
CCRIS 1061
ACETOHYDROXAMIC ACID, N-4-BIPHENYLYL-
N-Hydroxy-4-(acetylamino)biphenyl
N-(1,1'-Biphenyl)-4-yl-N-hydroxyacetamide
4-Acetamido-N-hydroxybiphenyl
BRN 2807692
CHEBI:16434
N-hydroxy-N-4-acetylaminobiphenyl
N-(4-biphenylyl)acetohydroxamic acid
Acetamide, N-[1,1'-biphenyl]-4-yl-N-hydroxy-
N-([1,1'-biphenyl]-4-yl)-N-hydroxyacetamide
Acetamide, N-(1,1'-biphenyl)-4-yl-N-hydroxy-
N-hydroxy-N-(4-phenylphenyl)-acetamide
N-((1,1'-biphenyl)-4-yl)-N-hydroxyacetamide
Acetamide, N-(1,1'-biphenyl)-4-yl-N-hydroxy-(9CI)
unhsjqxrzciatf-uhfffaoysa-n
N-hydroxy-N-(4-phenylphenyl)acetamide
V62MEG9TQB
CHEMBL279548
SCHEMBL3345880
DTXSID7020718
Hydroxy-4-acetylaminobiphenyl, N-
N-(4-Biphenyl)acetohydroxamic acid
C04081
N-[1,1'-Biphenyl]-4-yl-N-hydroxyacetamide #
Q27101903