Skip to main content

N-hydroxy-N-(4-phenylphenyl)benzamide

ADVERTISEMENT
Identification
Molecular formula
C19H15NO2
CAS number
35947-07-0
IUPAC name
N-hydroxy-N-(4-phenylphenyl)benzamide
State
State

This compound exists as a solid at room temperature. It is characterized by its stable crystalline structure, making it easy to handle and store under standard laboratory conditions.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
379.00
Boiling point (Kelvin)
652.15
General information
Molecular weight
291.34g/mol
Molar mass
291.3390g/mol
Density
1.2239g/cm3
Appearence

N-hydroxy-N-(4-phenylphenyl)benzamide is a crystalline solid with a pale yellow to white appearance. It is typically seen as a powder or in crystalline form, depending on the level of purity and processing it has undergone. The crystals are usually fine and can be quite delicate.

Comment on solubility

Solubility of N-hydroxy-N-(4-phenylphenyl)benzamide

N-hydroxy-N-(4-phenylphenyl)benzamide, a compound with a complex structure, exhibits interesting solubility characteristics. Understanding its solubility can be essential for its application in various chemical processes and formulations.

Solubility Characteristics

The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of the hydroxy group (-OH) tends to increase the polarity of the molecule, potentially enhancing its solubility in polar solvents.
  • Hydrogen Bonding: The ability of N-hydroxy-N-(4-phenylphenyl)benzamide to form hydrogen bonds may improve its solubility in solvents like water and alcohols.
  • Temperature: Increasing temperature often enhances solubility; therefore, this compound may display better solubility at elevated temperatures.
  • Solvent Type: The solubility may vary significantly between different solvents. For instance, it may be more soluble in organic solvents such as ethanol or methanol compared to water.

As a practical note, it is often said that "like dissolves like," meaning the nature of the solvent plays a critical role in the solubility of N-hydroxy-N-(4-phenylphenyl)benzamide. Thus, choosing the right solvent is crucial for maximizing its solubility.

This compound's unique structure results in a distinctive balance between hydrophobic and hydrophilic properties, making its solubility both a challenge and an opportunity in chemical applications.

Interesting facts

Interesting Facts about N-hydroxy-N-(4-phenylphenyl)benzamide

N-hydroxy-N-(4-phenylphenyl)benzamide is a fascinating compound with several notable characteristics and applications, particularly in the field of medicinal chemistry. Here are some intriguing insights about this compound:

  • Biological Activity: This compound has been studied for its potential biological activity. Its structure suggests that it may possess properties that could inhibit certain enzymes or act as a modulator in biochemical pathways.
  • Synthetic Routes: The synthesis of N-hydroxy-N-(4-phenylphenyl)benzamide often involves various condensation reactions. The ability to modify its structure opens avenues for the creation of derivatives that could enhance its efficacy or alter its properties.
  • Applications: As a chemical entity, it has potential applications in pharmaceuticals, particularly in developing drugs targeting specific diseases. Researchers are exploring its role in cancer therapy due to its structural composition that may impact cell signaling pathways.
  • Role in Organic Chemistry: This compound is a prime example of how modifying an amide group can lead to vastly different chemical behaviors. The introduction of hydroxy and phenyl groups can influence both the reactivity and physical properties of the compound.
  • Functional Group Significance: The presence of the N-hydroxy group is especially interesting. Hydroxamates like this are often explored for their ability to chelate metal ions, which can be a critical feature in drug design.

As a chemistry student or scientist, understanding compounds like N-hydroxy-N-(4-phenylphenyl)benzamide provides valuable insights into the complexities of organic molecules and their potential applications in healthcare and beyond. Each modification can lead to new discoveries, making this compound a noteworthy subject of study!


Synonyms
N-Hydroxy-4-biphenylylbenzamide
26690-77-7
N-(1,1'-Biphenyl)-4-yl-N-hydroxybenzamide
RefChem:163497
N-hydroxy-N-(4-phenylphenyl)benzamide
N-Hydroxy-4-biphenylbenzamide
BRN 2746331
N-4-Biphenylylbenzohydroxamic acid
BENZOHYDROXAMIC ACID, N-4-BIPHENYLYL-
DTXSID80949509
N-([1,1'-Biphenyl]-4-yl)-N-hydroxybenzamide