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N-hydroxy-N-(4-styrylphenyl)acetamide

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Identification
Molecular formula
C16H15NO2
CAS number
6264-45-5
IUPAC name
N-hydroxy-N-(4-styrylphenyl)acetamide
State
State

At room temperature, N-hydroxy-N-(4-styrylphenyl)acetamide exists as a solid. This is common for its class of organic compounds.

Melting point (Celsius)
139.00
Melting point (Kelvin)
412.15
Boiling point (Celsius)
312.00
Boiling point (Kelvin)
585.15
General information
Molecular weight
239.30g/mol
Molar mass
239.2810g/mol
Density
1.2010g/cm3
Appearence

This compound appears as a solid crystalline material. The color can range from white to off-white, depending largely on the purity and synthesis conditions.

Comment on solubility

Solubility of N-hydroxy-N-(4-styrylphenyl)acetamide

N-hydroxy-N-(4-styrylphenyl)acetamide, known for its unique structural features, exhibits interesting solubility characteristics that are influenced by its molecular structure. Understanding its solubility is essential for both theoretical and practical applications. Here are some key points:

  • Polar vs. Non-polar Interactions: Its amide group is polar, which generally aids in solubility in polar solvents. However, the presence of the styryl group contributes non-polar character, creating a balanced nature.
  • Solvent Compatibility: This compound is likely to dissolve readily in solvents such as methanol and dimethyl sulfoxide (DMSO) due to their ability to interact with the polar amide group.
  • Limited Aqueous Solubility: Despite its potential for solubility in organic solvents, N-hydroxy-N-(4-styrylphenyl)acetamide may exhibit poor solubility in water, which is a common trait among many organic compounds with large hydrophobic portions.

To optimize its use in various chemical applications, it is essential to consider these solubility traits. A practical approach includes:

  1. Testing different solvent systems to determine the most effective one for dissolution.
  2. Utilizing temperature control to enhance solubility when necessary.
  3. Exploring co-solvent strategies that can assist in improving water solubility.

In conclusion, the solubility of N-hydroxy-N-(4-styrylphenyl)acetamide is dictated by its unique molecular interactions. Understanding these properties is critical for leveraging its potential in diverse applications.

Interesting facts

Exploring N-hydroxy-N-(4-styrylphenyl)acetamide

N-hydroxy-N-(4-styrylphenyl)acetamide is a fascinating compound that has garnered interest in various fields, particularly in organic chemistry and medicinal research. Here are some intriguing facts about this compound:

  • Functional Groups: This compound contains a hydroxyl group (-OH) and an acetamide moiety. Such functional groups are crucial in determining the compound's reactivity and potential biological activities.
  • Potential Applications: Due to its unique structure, N-hydroxy-N-(4-styrylphenyl)acetamide may have applications in pharmaceuticals, particularly as a potential therapeutic agent. It can be explored for its anti-inflammatory or analgesic properties.
  • Structure-Activity Relationship: The presence of the styryl group suggests that this compound can interact with biological targets, leading to a rich area for study in medicinal chemistry. Understanding how structural variations affect activity can lead to the development of more effective drugs.
  • Research Interest: Scientists are intrigued by the compound's ability to act as a protective agent against oxidative stress, making it a candidate for research in neuroprotection.

"The beauty of chemistry is that small changes in structure can lead to big changes in function." This quote encapsulates the essence of exploring compounds like N-hydroxy-N-(4-styrylphenyl)acetamide. The ongoing research into such compounds continues to unveil their potential, contributing to advancements in both science and medicine.

In summary, N-hydroxy-N-(4-styrylphenyl)acetamide not only represents an interesting molecule from a structural perspective but also holds promise for various applications in modern chemistry.

Synonyms
N-hydroxy-N-[4-(2-phenylethenyl)phenyl]acetamide
MLS003389289
NCIOpen2_005365
CHEMBL1872651
DTXSID801239735
SMR002048944