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N-hydroxy-N-(7-hydroxy-9H-fluoren-2-yl)acetamide

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Identification
Molecular formula
C15H13NO3
CAS number
127241-11-8
IUPAC name
N-hydroxy-N-(7-hydroxy-9H-fluoren-2-yl)acetamide
State
State

At room temperature, this compound exists in a solid state. It is likely relatively stable due to the aromatic character of the fluorenyl group within the molecule.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
241.27g/mol
Molar mass
241.2450g/mol
Density
1.3750g/cm3
Appearence

The compound is likely to appear as a crystalline solid, given its complex organic structure and aromatic components. The presence of hydroxyl groups suggests potential interactions such as hydrogen bonding, which can influence the crystalline lattice arrangement.

Comment on solubility

Solubility of N-hydroxy-N-(7-hydroxy-9H-fluoren-2-yl)acetamide

The solubility of N-hydroxy-N-(7-hydroxy-9H-fluoren-2-yl)acetamide can be classified based on its molecular structure and functional groups. Understanding its solubility properties is essential for its applications in various chemical processes. Here are some key points regarding its solubility:

  • Polar vs. Nonpolar: The presence of the hydroxyl groups (-OH) in this compound suggests a potential for polar interactions, which may enhance its solubility in polar solvents such as water.
  • Molecular Interactions: The ability to form hydrogen bonds due to the hydroxyl groups can significantly influence solubility. Compounds capable of hydrogen bonding typically exhibit better solubility in polar solvents.
  • Aromatic Influence: The fluorenyl moiety may introduce some hydrophobic characteristics, potentially limiting solubility in highly polar solvents while enhancing it in organic solvents.
  • pH Dependency: The solubility may also be affected by the pH of the solution, as ionization of the functional groups can alter interactions with the solvent.

In conclusion, the solubility of N-hydroxy-N-(7-hydroxy-9H-fluoren-2-yl)acetamide is likely to be:

  • Good in polar solvents due to hydrogen bonding capabilities.
  • Variable in nonpolar solvents, depending on the concentration of aromatic characteristics and molecular structure influences.

Ultimately, experimental data would provide the most accurate understanding of its solubility profile across different environments.

Interesting facts

Interesting Facts about N-hydroxy-N-(7-hydroxy-9H-fluoren-2-yl)acetamide

N-hydroxy-N-(7-hydroxy-9H-fluoren-2-yl)acetamide is a compound that demonstrates fascinating properties and applications in the field of organic chemistry and pharmaceuticals. Here are some noteworthy insights:

  • Biological Activity: This compound exhibits promising biological activity, particularly in the arena of medicinal chemistry. Its structure provides a basis for developing novel therapeutic agents.
  • Fluorene Derivative: As a derivative of fluorene, a polycyclic aromatic hydrocarbon, it has attracted attention for its unique electronic properties. Fluorene compounds are often studied for their potential use in organic light-emitting diodes (OLEDs) and other electronic applications.
  • Hydroxyl Groups: The presence of hydroxyl functional groups not only increases its solubility but also contributes to its reactivity. These groups are often crucial in facilitating various chemical reactions.
  • Interactions with Biological Systems: The hydroxyl groups may enhance interactions with biological macromolecules, such as proteins and nucleic acids, making this compound a candidate for further study in drug design.
  • Research Applications: N-hydroxy-N-(7-hydroxy-9H-fluoren-2-yl)acetamide can serve as a model compound in research focused on understanding the mechanisms of drug action and development.

In summary, this compound stands out not only for its chemical uniqueness but also for the potential implications in pharmaceutical development and materials science. As research continues to unfold, N-hydroxy-N-(7-hydroxy-9H-fluoren-2-yl)acetamide may pave the way for innovative advancements in various scientific disciplines.

Synonyms
14461-87-1
N-hydroxy-N-(7-hydroxy-9H-fluoren-2-yl)acetamide
ACETOHYDROXAMIC ACID, N-(7-HYDROXYFLUOREN-2-YL)-
N-(7-Hydroxyfluoren-2-yl)acetohydroxamic acid
N-Hydroxy-N-(7-hydroxy-2-fluorenyl)acetamide
DTXSID20162770