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Paracetamol

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Identification
Molecular formula
C8H9NO2
CAS number
103-90-2
IUPAC name
N-hydroxy-N-(p-tolyl)acetamide
State
State

At room temperature, paracetamol is in a solid state; it is a stable compound under normal conditions.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.00
Boiling point (Celsius)
327.86
Boiling point (Kelvin)
601.01
General information
Molecular weight
151.16g/mol
Molar mass
151.1630g/mol
Density
1.2633g/cm3
Appearence

Paracetamol is typically a white, crystalline solid. It is often in the form of powder or granules in its pure state, suitable for chemical and pharmaceutical purposes.

Comment on solubility

Solubility of N-hydroxy-N-(p-tolyl)acetamide

N-hydroxy-N-(p-tolyl)acetamide, known for its intriguing chemical properties, exhibits specific solubility traits that are important for its application in various fields. The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of both hydroxyl and amide functional groups suggests that the compound can engage in hydrogen bonding, which may enhance its solubility in polar solvents such as water.
  • Temperature: Like many organic compounds, solubility may increase with rising temperature, allowing for greater dissolution of N-hydroxy-N-(p-tolyl)acetamide in certain solvents.
  • Solvent Choice: This compound may be more soluble in organic solvents like methanol or ethanol due to the aromatic p-tolyl group, which increases hydrophobic interactions.

It's worth noting that while certain generalizations can be made, actual solubility may vary based on conditions such as pH and the presence of other solutes. For practical purposes, conducting solubility tests in relevant solvents is essential to determine the most favorable conditions for use.

In summary, understanding the solubility of N-hydroxy-N-(p-tolyl)acetamide requires consideration of multiple factors, making it a fascinating compound to study in the context of organic chemistry.

Interesting facts

Interesting Facts about N-hydroxy-N-(p-tolyl)acetamide

N-hydroxy-N-(p-tolyl)acetamide is a compound that serves as an important molecule in various chemical and biological processes. Here are some intriguing aspects of this compound that highlight its significance:

  • Pharmaceutical Relevance: This compound is often studied for its potential role in drug development, particularly in targeting specific enzymes and pathways in human biology. Its structural characteristics offer opportunities for modifying pharmacological properties.
  • Mechanism of Action: N-hydroxy-N-(p-tolyl)acetamide is known to act as an inhibitor of certain enzymes. This mechanism has implications in the design of inhibitors that prevent disease progression, making it valuable in medicinal chemistry.
  • Synthetic Utility: The methods of synthesizing N-hydroxy-N-(p-tolyl)acetamide are of keen interest to chemists. Synthetic pathways often involve reaction conditions that allow for the optimization of yield and purity, showcasing the compound’s versatility in the laboratory.
  • Structural Insights: The presence of the p-tolyl group plays a crucial role in the compound's spatial configuration, affecting how it interacts with other molecules. Understanding these interactions is essential for molecular design.
  • Research Potential: Ongoing research is aimed at exploring the broader implications of this compound in various fields such as agriculture and biotechnology, revealing its multifaceted nature.

As a scientist or chemistry student, delving into compounds like N-hydroxy-N-(p-tolyl)acetamide not only enriches your understanding of organic chemistry but also showcases the intersection of chemistry with real-world applications.

Synonyms
N-Hydroxy-N-(4-methylphenyl)acetamide
27451-21-4
N-(4-Methylphenyl)acetohydroxamic acid
DTXSID00181868
RefChem:162185
DTXCID40104359
Acetamide, N-hydroxy-N-(4-methylphenyl)-
N-Hydroxy-acet-para-toluidid
ACETOHYDROXAMIC ACID, N-(p-TOLYL)-
CCRIS 5142
N-Hydroxy-acet-para-toluidid [German]
BRN 2937345
N-hydroxy-4-methylacetanilide
CHEMBL156553
N-Acetyl-N-hydroxy-p-toluidine
SCHEMBL3279618
DKXQDOLWLOYQOK-UHFFFAOYSA-N
N-Hydroxy-N-(4-methylphenyl)acetamide #