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Memantine hydrochloride

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Identification
Molecular formula
C12H22ClN
CAS number
41100-52-1
IUPAC name
N-isobutyladamantan-1-amine;hydrochloride
State
State

At room temperature, memantine hydrochloride is in a solid state.

Melting point (Celsius)
292.00
Melting point (Kelvin)
565.15
Boiling point (Celsius)
193.00
Boiling point (Kelvin)
466.15
General information
Molecular weight
215.77g/mol
Molar mass
215.7700g/mol
Density
1.0040g/cm3
Appearence

Memantine hydrochloride appears as a white to off-white crystalline powder. It is soluble in water and slightly soluble in alcohol.

Comment on solubility

Solubility of N-isobutyladamantan-1-amine Hydrochloride

N-isobutyladamantan-1-amine hydrochloride is a compound whose solubility characteristics are particularly influenced by its molecular structure and the presence of the hydrochloride salt form. Understanding its solubility can provide valuable insights for various applications, particularly in pharmaceutical contexts.

Solubility Properties

This compound is generally soluble in:

  • Water: The hydrochloride form typically enhances solubility in polar solvents like water due to the ionic nature of the salt.
  • Alcohols: Moderate solubility in alcohols can also be expected, as they can engage in hydrogen bonding with the amine functional groups.
  • Organic Solvents: Limited solubility in non-polar organic solvents is likely due to its polar nature.

In summary, the solubility of N-isobutyladamantan-1-amine hydrochloride is a combination of its polar characteristics and ionic interactions, making it more soluble in polar solvents. As emphasized, the **hydrochloride** form significantly affects solubility properties, setting it apart from its base counterpart. Understanding these solubility traits is essential for optimal utilization in research and development.

Interesting facts

Interesting Facts About N-isobutyladamantan-1-amine Hydrochloride

N-isobutyladamantan-1-amine hydrochloride is a fascinating compound with unique properties and applications. Here are several engaging points to consider:

  • Structural Characteristics: This compound features an adamantane structure, which is a diamond-like carbon framework. Such structures are known for their stability and rigidity, making them intriguing for various chemical applications.
  • Pharmacological Interest: As an amine, N-isobutyladamantan-1-amine hydrochloride is of particular interest in medicinal chemistry. Compounds with similar structures are studied for their potential as drugs, especially in the fields of neuropharmacology and psychiatry.
  • Application in Drug Design: The unique framework of adamantane derivatives is often explored in drug design. The 3D shape of adamantane can help improve the bioavailability and selectivity of pharmaceutical agents.
  • Research and Development: Current research might focus on the synthesis of this compound and its derivatives, exploring how modifications can enhance its efficacy or reduce side effects in medicinal applications.
  • Potential in Material Science: The stability and molecular characteristics of adamantane structures open doors for uses beyond medicine, potentially in the development of advanced materials or nanotechnology.

"The world of chemical compounds is filled with surprises and opportunities for innovation!"

This compound exemplifies the intersection of organic chemistry and pharmacology, making it a valuable subject for ongoing research and application. Its unique features and potential capabilities contribute to the rich tapestry of chemical compounds currently being investigated.

Synonyms
N-Isobutyl-1-adamantanamine hydrochloride
1-ADAMANTANAMINE, N-ISOBUTYL-, HYDROCHLORIDE
23479-44-9
DTXSID60178037
RefChem:227368
DTXCID90100528