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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
N-isopropyl-3-(5-nitro-2-furyl)prop-2-enamide
State
State

At room temperature, nitrofurazone is a solid. It is generally found in crystalline form and belongs to the class of nitro compounds used for its antibacterial properties.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
233.00
Boiling point (Kelvin)
506.15
General information
Molecular weight
198.16g/mol
Molar mass
198.1560g/mol
Density
1.7940g/cm3
Appearence

Nitrofurazone typically appears as a yellow crystalline solid in pure form. It may also be encountered as a fine yellow powder. Its distinct color is characteristic of many nitro compounds, attributed to the nitro group attached to an aromatic ring.

Comment on solubility

Solubility of N-isopropyl-3-(5-nitro-2-furyl)prop-2-enamide

N-isopropyl-3-(5-nitro-2-furyl)prop-2-enamide is known to exhibit intriguing solubility characteristics, influenced by its molecular structure and functional groups. Its solubility can be discussed in the following contexts:

  • Polar and Non-polar Solvents: This compound tends to be more soluble in polar solvents due to the presence of nitro and amide functional groups, which can engage in hydrogen bonding.
  • Water Solubility: While specific solubility values in water may not be well-documented, the structure suggests limited water solubility because of the hydrophobic isopropyl group.
  • Organic Solvent Compatibility: Conversely, it is likely to dissolve well in organic solvents such as ethanol, methanol, or acetone which can stabilize non-polar regions and interact with polar functional groups.
  • Temperature Influence: As with many organic compounds, solubility may improve with increasing temperature, potentially enhancing interactions with solvent molecules.

In summary, N-isopropyl-3-(5-nitro-2-furyl)prop-2-enamide’s solubility dynamics are largely dependent on the solvent environment, making it a compound of interest when considering applications in various chemical contexts. Understanding the solubility can significantly inform its potential uses and reactivity in synthetic pathways.

Interesting facts

Interesting Facts about N-isopropyl-3-(5-nitro-2-furyl)prop-2-enamide

N-isopropyl-3-(5-nitro-2-furyl)prop-2-enamide is a fascinating compound, especially within the realm of organic chemistry. This compound is notable for several reasons:

  • Chemical Structure: The presence of the nitro group (–NO2) attached to the furan ring contributes significantly to the compound's reactivity and potential applications in medicinal chemistry.
  • Biological Activity: Compounds containing furan and nitro groups have been studied for their biological properties, with some exhibiting antimicrobial and anticancer activities. Research into such compounds often leads to the discovery of new drugs.
  • Synthetic Routes: The synthesis of N-isopropyl-3-(5-nitro-2-furyl)prop-2-enamide can involve various synthetic strategies, highlighting the creativity and problem-solving skills of chemists. Techniques like condensation reactions and functional group modifications are commonly employed.
  • Applications: Besides its potential in pharmaceuticals, compounds like this may serve as intermediates in organic synthesis, allowing for the creation of more complex molecules.
  • Research Potential: This compound can serve as a basis for further investigation into the structure-activity relationships of biologically active compounds, providing insights that could enhance drug design.

In summary, N-isopropyl-3-(5-nitro-2-furyl)prop-2-enamide is more than just a simple compound; it embodies the intricate interplay between structure and function in the world of organic chemistry. As a chemist, exploring such compounds opens doors to understanding novel therapeutic agents and the mechanisms behind their activity.