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Amantadine

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Identification
Molecular formula
C10H17NH2
CAS number
768-94-5
IUPAC name
N-isopropyladamantan-1-amine
State
State

At room temperature, Amantadine is in a solid state, typically in the form of a crystalline powder.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.20
Boiling point (Celsius)
213.50
Boiling point (Kelvin)
486.70
General information
Molecular weight
151.26g/mol
Molar mass
151.2570g/mol
Density
1.0000g/cm3
Appearence

Amantadine appears as a white or nearly white crystalline powder. It is typically odorless or may have a faint ammonia-like smell.

Comment on solubility

Solubility of N-isopropyladamantan-1-amine

N-isopropyladamantan-1-amine, characterized by its unique amine functional group and adamantane structure, exhibits intriguing solubility properties. Understanding its solubility can be approached from several angles:

  • Solvent Compatibility: The compound is likely to be soluble in polar organic solvents such as methanol or ethanol due to the presence of the amine group.
  • Hydrophobic Characteristics: The adamantane framework contributes to its hydrophobic nature, potentially limiting solubility in water and non-polar solvents.
  • Temperature Effects: Like many amines, solubility may increase with temperature, enhancing molecular movement and interactions with solvents.
  • Concentration Factors: At higher concentrations, the solubility might exhibit saturation points that should be considered in practical applications.

To summarize, while the solubility of N-isopropyladamantan-1-amine may vary significantly depending on the solvent and environmental conditions, it tends to favor polar environments. To accurately determine its solubility characteristics, empirical testing in various solvents is advisable. As you explore this compound, keep in mind the words of chemists: “The solubility is the gateway to understanding the reactivity and functionality of a compound.”

Interesting facts

Exploring N-Isopropyladamantan-1-amine

N-Isopropyladamantan-1-amine is an intriguing compound that belongs to the class of amines and is characterized by its unique structure derived from adamantane, a polycyclic hydrocarbon. This compound is particularly interesting to researchers and industry professionals for several reasons:

  • Structure Matters: The adamantane backbone provides a rigid and stable molecular structure, which contributes to its potential in various chemical applications and pharmacological properties.
  • Potential Applications: N-Isopropyladamantan-1-amine is being investigated for its role as a pharmaceutical intermediate. Its unique structural properties might make it suitable for developing novel therapeutic agents.
  • Cognitive Effects: Some studies suggest that compounds related to adamantane have neuroprotective and cognitive-enhancing effects, sparking interest in their application within the fields of neurology and psychiatry.
  • Research Opportunities: The combination of the isopropyl group with the adamantane core creates opportunities for targeted modifications that could lead to new derivatives with improved efficacy or reduced side effects.
  • Versatile Reactions: As an amine, N-isopropyladamantan-1-amine can undergo a variety of chemical reactions, making it a valuable compound for synthetic organic chemistry.

The study of this compound exemplifies how a single structural modification can lead to diverse functionalities and a wealth of research opportunities in both basic and applied chemistry.

In Conclusion

Examining compounds like N-Isopropyladamantan-1-amine reveals the fascinating interplay between structure and function in organic chemistry. Whether for therapeutic applications or advanced materials, the potential of such compounds continues to inspire scientific exploration and innovation.

Synonyms
Tricyclo(3.3.1.1(3,7))decan-1-amine, N-(1-methylethyl)-
N-isopropyladamantan-1-amine
3667-90-1
N-(1-Methylethyl)tricyclo(3.3.1.1(3,7))decan-1-amine
SCHEMBL105165
DTXSID50190122
FSMRLILYPRGBDS-UHFFFAOYSA-N
Tricyclo[3.3.1.1]decan-1-amine, N-(1-methylethyl)-