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Memantine hydrochloride

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Identification
Molecular formula
C12H21N·HCl
CAS number
41100-52-1
IUPAC name
N-isopropyladamantan-1-amine;hydrochloride
State
State

At room temperature, memantine hydrochloride is a solid.

Melting point (Celsius)
292.00
Melting point (Kelvin)
565.15
Boiling point (Celsius)
229.00
Boiling point (Kelvin)
502.00
General information
Molecular weight
215.77g/mol
Molar mass
215.7680g/mol
Density
1.1004g/cm3
Appearence

Memantine hydrochloride appears as a white to off-white crystalline powder. It is typically odorless.

Comment on solubility

Solubility of N-isopropyladamantan-1-amine;hydrochloride

N-isopropyladamantan-1-amine;hydrochloride is a quaternary ammonium compound that exhibits intermediate solubility properties in various solvents. Understanding its solubility behavior is crucial for applications in pharmaceuticals and chemical research. Here are some key points regarding its solubility:

  • Water Solubility: The hydrochloride form typically displays increased solubility in water due to the presence of the ionic functional groups, which facilitates hydration.
  • Organic Solvents: In organic solvents, the solubility can vary. It is generally more soluble in polar solvents such as ethanol or methanol compared to non-polar solvents.
  • pH Dependency: The solubility might be influenced by the pH of the solution. As a quaternary amine salt, it will behave differently in acidic versus basic conditions.
  • Temperature Effects: Like many compounds, solubility may increase with temperature, making higher temperatures favorable for dissolution.

In summary, the solubility of N-isopropyladamantan-1-amine;hydrochloride is characterized by its ionic nature, which enhances solubility in water and polar organic solvents, while also being sensitive to environmental factors such as pH and temperature. Understanding these solubility characteristics is essential for effective application and formulation in various chemical processes.

Interesting facts

Interesting Facts about N-isopropyladamantan-1-amine Hydrochloride

N-isopropyladamantan-1-amine hydrochloride is a fascinating compound with various applications and interesting characteristics. Here are some noteworthy aspects to consider:

  • Structural Uniqueness: This compound features a unique adamantane core, a structure known for its three-dimensional cage-like shape, which contributes to its distinct chemical properties.
  • CNS Activity: N-isopropyladamantan-1-amine is noted for its potential activity in the central nervous system (CNS). It is being studied for possible therapeutic effects, particularly in the context of neurological disorders.
  • Pharmaceutical Relevance: Due to its amine functionality, this compound is of interest to pharmaceutical researchers in drug design. It could serve as a lead compound for developing novel medications.
  • Isopropyl Group Influence: The isopropyl group in its structure may enhance lipid solubility, influencing how the compound interacts within biological systems.

Quotes from Research

In the field of medicinal chemistry, researchers often refer to compounds like N-isopropyladamantan-1-amine hydrochloride as having "inherent potential for overcoming blood-brain barrier challenges." This is pivotal in drug development aimed at CNS targets.

Future Perspectives

As research progresses, N-isopropyladamantan-1-amine hydrochloride may reveal even more applications and benefits in various fields, including:

  • Neurology
  • Pharmacology
  • Material Science

As a scientist or a chemistry student, the study of such compounds not only enhances our understanding of chemical properties and interactions but also demonstrates the exciting potential of chemistry in developing solutions for real-world problems.

Synonyms
N-Isopropyl-1-adamantanamine hydrochloride
1-ADAMANTANAMINE, N-ISOPROPYL-, HYDROCHLORIDE
3667-91-2
DTXSID10190123
DTXCID20112614