Skip to main content

N-(isopropylideneamino)benzamide

ADVERTISEMENT
Identification
Molecular formula
C10H12N2O
CAS number
5351-15-9
IUPAC name
N-(isopropylideneamino)benzamide
State
State

At room temperature, N-(Isopropylideneamino)benzamide is in a solid state. It is typically handled as a powder or in crystalline form, maintaining its stability under standard conditions.

Melting point (Celsius)
85.00
Melting point (Kelvin)
358.15
Boiling point (Celsius)
327.80
Boiling point (Kelvin)
600.95
General information
Molecular weight
176.22g/mol
Molar mass
176.2210g/mol
Density
1.0637g/cm3
Appearence

N-(Isopropylideneamino)benzamide is typically found as a crystalline solid. The appearance is characterized by white to off-white crystals or powder. It is important to store it in a cool, dry place and to handle it with care to maintain its stability and prevent decomposition.

Comment on solubility

Solubility of N-(isopropylideneamino)benzamide

N-(isopropylideneamino)benzamide, with the chemical formula C11H14N2O, exhibits notable solubility characteristics that are of interest in various chemical contexts. Here are some key points regarding its solubility:

  • Solvent Dependence: This compound shows varying levels of solubility depending on the solvent employed. It may be soluble in organic solvents like ethanol and dimethyl sulfoxide (DMSO), but can be poorly soluble in water.
  • Polar vs. Non-Polar: The presence of both polar (amine and carbonyl) and non-polar (aromatic ring) functional groups indicates that N-(isopropylideneamino)benzamide is more soluble in polar organic solvents compared to non-polar solvents.
  • Temperature Effects: Like many organic compounds, solubility can be enhanced with increased temperature. Thus, heating the solvent can provide better dissolution.
  • pH Influence: The solubility may also be influenced by the pH of the solution, particularly because the amine group can become protonated, thereby affecting the overall polarity and interaction with water.

In summary, while N-(isopropylideneamino)benzamide has some solubility in polar organic solvents, its behavior under various conditions is complex. Understanding its solubility properties can offer valuable insights for applications in pharmaceuticals and organic synthesis.

Interesting facts

Interesting Facts about N-(isopropylideneamino)benzamide

N-(isopropylideneamino)benzamide is a fascinating compound within the realm of organic chemistry, primarily known for its role in various chemical reactions and synthetic strategies. Here are some noteworthy aspects of this compound:

  • Structure and Characterization: The unique structure of N-(isopropylideneamino)benzamide features an isopropylidene group attached to the amino function, which introduces interesting steric and electronic effects that can influence its reactivity and interactions.
  • Applications: This compound is notably used in:
    • Organic synthesis, particularly in the preparation of other more complex organic molecules.
    • Pharmaceutical research, where it may serve as a precursor or intermediate in drug development.
  • Reactivity: The presence of the amide functional group provides a site for hydrogen bonding and various chemical reactions, making it a versatile building block in organic synthesis. It can participate in:
    • Nucleophilic substitutions
    • Condensations
    • Coupling reactions
  • Importance in Medicinal Chemistry: Compounds like N-(isopropylideneamino)benzamide are significant in medicinal chemistry because they can exhibit biological activities. Understanding their properties can lead to the discovery of new therapeutic agents.
  • Research Interests: Ongoing studies may focus on the compound’s potential applications in functionally diverse materials or its effects in biological systems, making it a subject of keen interest in contemporary research.

In summary, N-(isopropylideneamino)benzamide demonstrates unique chemical properties that position it as a valuable compound for both research and application in organic and medicinal chemistry. Its multifunctional reactivity showcases the chemistry behind amides, and its applications underscore the importance of synthetic organic compounds in modern science.

Synonyms
Acetone benzoylhydrazone
3408-16-0
BENZOIC ACID, ISOPROPYLIDENEHYDRAZIDE
Isopropanone benzoylhydrazone
N-(propan-2-ylideneamino)benzamide
N'-(1-methylethylidene)benzohydrazide
6BA3BD9JR1
Benzoic acid, (1-methylethylidene)hydrazide
NSC-50992
NSC-170280
N'-(propan-2-ylidene)benzohydrazide
NSC 50992
P 1053
NSC 170280
BRN 1943256
AI3-21125
PhCON2 Me2CO de
UNII-6BA3BD9JR1
4-09-00-00924 (Beilstein Handbook Reference)
SCHEMBL1562144
N-(isopropylideneamino)benzamide
DTXSID30187676
HMS1577L15
NSC50992
NSC170280
STK119549
AKOS001469728
SDCCGMLS-0064776.P001
NCGC00338520-01
1-Benzoyl-2-(propan-2-ylidene)hydrazone
N-BENZOYL-N'-ISOPROPYLIDENEHYDRAZINE
AB00626716-03
BENZOIC ACID, 2-(1-METHYLETHYLIDENE)HYDRAZIDE
Z57101751