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N-(m-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide

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Identification
Molecular formula
C16H20N4O2
CAS number
5542-80-9
IUPAC name
N-(m-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide
State
State

At room temperature, N-(m-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide is typically found in a solid state. It is stable under standard conditions of temperature and pressure but may require special conditions for storage to prevent degradation.

Melting point (Celsius)
220.90
Melting point (Kelvin)
494.05
Boiling point (Celsius)
474.15
Boiling point (Kelvin)
747.30
General information
Molecular weight
285.32g/mol
Molar mass
285.3150g/mol
Density
0.9862g/cm3
Appearence

N-(m-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide typically appears as a crystalline solid. The color can vary but is often white or off-white, and it may have a slight odor characteristic of amides. It is generally handled as a powder or solid bulk material.

Comment on solubility

Solubility Information

The compound N-(m-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide is known for its unique solubility characteristics, which can greatly influence its application in various chemical processes. Understanding its solubility is crucial for effective utilization in chemical reactions and formulations.

Key Solubility Insights

  • Solvent Affinity: The solubility of this compound tends to be favorable in polar solvents such as dimethyl sulfoxide (DMSO) and methanol, due to the presence of both hydrophobic (m-tolylmethyl) and hydrophilic (hydrazine and carbonyl) functional groups.
  • Temperature Dependence: As with many organic compounds, solubility is generally enhanced with increasing temperature. This is particularly important when preparing solutions for synthesis or analysis.
  • pH Influence: The solubility may also be affected by pH, especially since the compound contains a hydrazine group that can interact with acidic or basic environments, thus altering its protonation state.

In summary, the solubility behavior of N-(m-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide is multifaceted and can be tailored through the choice of solvent, temperature, and pH. Understanding these factors can pave the way for devising more effective methodologies in both research and practical applications.

Interesting facts

Interesting Facts about N-(m-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide

N-(m-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide is a compound that showcases the intriguing relationship between structure and biological activity. Here are some noteworthy aspects of this compound:

  • Complex Structure: This compound features a multi-functional structure incorporating both hydrazine and amide functionalities. Such complexity can lead to interesting interactions with biological targets.
  • Pyridine Moiety: The presence of a pyridine ring contributes to the compound's potential for interacting with various enzymes and receptors due to its electron-withdrawing properties and ability to engage in hydrogen bonding.
  • Medicinal Chemistry: Compounds containing hydrazone and amide groups are of great interest in the field of medicinal chemistry. They often exhibit anti-tumor, anti-inflammatory, and anti-microbial activities, making them prime candidates for drug development.
  • Research Potential: As highlighted in several studies, compounds with similar structural motifs often reveal valuable insights for developing new therapeutic agents. Scientists are continuously exploring their potential within pharmacology.
  • Synthetic Routes: The synthesis of this compound can involve various organic reactions, including hydrazone formation and amide coupling. Understanding these synthetic pathways can illuminate broader synthetic strategies in organic chemistry.

The exploration and study of carbohydrates like N-(m-tolylmethyl)-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide not only enhance our fundamental understanding of chemical interactions but also pave the way for discovering new drugs that could potentially revolutionize treatment methodologies. As the saying goes, "The next great drug may be just one reaction away!"

Synonyms
P 1260
BRN 0495118
ISONICOTINIC ACID, 2-(2-((m-METHYLBENZYL)CARBAMOYL)ETHYL)HYDRAZIDE
15806-16-3
DTXSID90166361
DTXCID8088852