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N-methyl-2-(2-pyridyl)ethanamine

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Identification
Molecular formula
C8H12N2
CAS number
22255-81-0
IUPAC name
N-methyl-2-(2-pyridyl)ethanamine
State
State
The compound is typically a liquid at room temperature, which is characteristic for many simple amines of smaller molecular size.
Melting point (Celsius)
-12.00
Melting point (Kelvin)
261.15
Boiling point (Celsius)
197.00
Boiling point (Kelvin)
470.15
General information
Molecular weight
136.21g/mol
Molar mass
136.2070g/mol
Density
1.0280g/cm3
Appearence

This compound typically appears as a colorless to pale yellow liquid. It might have a slight amine-like odor.

Comment on solubility

Solubility of N-methyl-2-(2-pyridyl)ethanamine

The compound N-methyl-2-(2-pyridyl)ethanamine, with the chemical formula C8H12N2, displays notable solubility characteristics that are worth exploring. This organic compound belongs to the class of amines and contains both aliphatic and aromatic functions, influencing its solubility in various solvents.

Solubility Characteristics:

  • Polar Solvents: N-methyl-2-(2-pyridyl)ethanamine is generally soluble in polar solvents such as water and alcohols. This is due to the presence of the amine functional group that can engage in hydrogen bonding.
  • Non-polar Solvents: Its solubility in non-polar solvents can be limited, as the aromatic pyridine ring may not interact favorably with non-polar environments.
  • Saturation Behavior: When dissolved in a solvent, the saturation behavior can lead to distinct outcomes, as the solubility may vary with temperature and pressure, underscoring the relevance of solution conditions.

Furthermore, understanding the solubility of this compound can be crucial in practical applications, such as synthesis and formulation in different chemical environments. As a rule of thumb, "like dissolves like," which indicates that the solubility can be greatly affected by the polarity of the solvent.

In summary, N-methyl-2-(2-pyridyl)ethanamine exhibits good solubility in polar solvents while showcasing limited solubility in non-polar solvents. Its solubility characteristics make it a compound of interest in various chemical processes.

Interesting facts

Interesting Facts about N-methyl-2-(2-pyridyl)ethanamine

N-methyl-2-(2-pyridyl)ethanamine, commonly referred to as 2-(N-methylpyridin-2-yl)ethanamine, is a fascinating compound that has drawn the interest of chemists for various reasons, particularly in the fields of medicinal chemistry and organic synthesis.

Key Characteristics:

  • Structural Significance: This compound possesses a pyridine ring, which is a heterocyclic aromatic organic compound. The presence of a nitrogen atom in the ring enhances its reactivity and interaction with other molecules.
  • Biological Relevance: N-methyl-2-(2-pyridyl)ethanamine has been studied for its potential applications as a pharmacological agent. Compounds like this are often explored for their effects on the central nervous system.
  • Synthetic Versatility: The amine functional group allows for versatile reactivity; it can undergo various chemical transformations such as alkylation, acylation, and reductive amination.
  • Research and Development: Due to its structure, this compound serves as a building block in the synthesis of larger organic molecules, contributing to advancements in drug discovery.

Notable Applications:

Some key applications of N-methyl-2-(2-pyridyl)ethanamine include:

  • Investigation in the synthesis of complex molecules for therapeutic purposes.
  • Utilization in the development of high-performing catalysts in organic reactions.
  • The study of its interactions with biological receptors, which could lead to the identification of potential new drugs.

In summary, N-methyl-2-(2-pyridyl)ethanamine exemplifies the intricate relationships between molecular structure and function, and it stands as a beacon for ongoing research in both synthetic and medicinal chemistry. Scientists continue to explore its vast potentials, making compounds like this an essential part of the chemical research landscape.

Synonyms
betahistine
5638-76-6
2-(2-METHYLAMINOETHYL)PYRIDINE
N-methyl-2-(pyridin-2-yl)ethanamine
Vasomotal
2-Pyridineethanamine, N-methyl-
Serc base
N-Methyl-2-pyridineethanamine
Betahistina
beta-Histine
PT 9 base
2-[2-(Methylamino)ethyl]pyridine
N-methyl-2-pyridin-2-ylethanamine
Sinmenier (free base)
Betahistinum
N-Methyl-2-pyridineethylamine
methyl[2-(pyridin-2-yl)ethyl]amine
Betaistina [DCIT]
Serc
Betaistina
2-(2-(Methylamino)ethyl)pyridine
Pyridine, 2-(2-methylaminoethyl)-
Betahistine [INN:BAN]
Betahistinum [INN-Latin]
[2-(2-Pyridyl)ethyl]methylamine
Betahistina [INN-Spanish]
NSC 42617
Vestibo
(2-(2-Pyridyl)ethyl)methylamine
2-(beta-Methylaminoethyl)pyridine
.beta.-Histine
EINECS 227-086-4
Vestibo (TN)
Betahistine (INN)
Pyridine, 2-[2-(methylamino)ethyl]-
Betahistine hydrochloride
N-Methyl-N-beta-(2-pyridyl)ethylamine
BRN 0112294
HISTALEAN
Betahistine free base
CHEBI:35677
5638-76-6 (free base)
X32KK4201D
BETAHISTINE [MI]
N-Methyl-2-(2-pyridinyl)ethanamine
BETAHISTINE [INN]
NSC-42617
BETAHISTINE [VANDF]
BETAHISTINE [MART.]
N-Methyl-N-(2-pyridin-2-ylethyl)amine
BETAHISTINE [WHO-DD]
CHEMBL24441
DTXSID3022665
PYRIDINE, 2-(2-(METHYLAMINO)ETHYL)-
EC 227-086-4
5-22-09-00368 (Beilstein Handbook Reference)
2-(.beta.-Methylaminoethyl)pyridine
N-Methyl-2-(pyridin-2-yl)ethan-1-amine
N-Methyl-N-.beta.-(2-pyridyl)ethylamine
Betahistinum (INN-Latin)
Betahistina (INN-Spanish)
BETAHISTINE (MART.)
methyl(2-(pyridin-2-yl)ethyl)amine
Betahistine Biphar
Betahistine Methanesulphonate
Dihydrochloride, Betahistine
Methanesulfonate, Betahistine
N-Methyl-N-[2-(2-pyridyl)ethyl]amine
Methanesulphonate, Betahistine
UNII-X32KK4201D
Betahistine?
Ethyl nipicotate
MFCD00006362
Methyl-(2-pyridin-2-yl-ethyl)-amine
Spectrum_000274
Betahistine dihdrochloride
Prestwick0_000543
Prestwick1_000543
Prestwick2_000543
Prestwick3_000543
Spectrum2_001191
Spectrum3_001735
Spectrum4_000254
Spectrum5_001393
2-(methylaminoethyl)pyridine
(2-Methylaminoethyl)pyridine
BSPBio_000585
BSPBio_003410
KBioGR_000688
KBioSS_000754
methyl(2-pyridinyl)ethylamine
MLS000028903
DivK1c_000602
SCHEMBL125582
SPBio_001261
SPBio_002506
BPBio1_000645
cid_203875
DTXCID202665
OBE101
2-(2(methylamino)ethyl)pyridine
2-(2-methylaminoethyl) pyridine
BDBM96589
GTPL11937
KBio1_000602
KBio2_000754
KBio2_003322
KBio2_005890
KBio3_002630
EX-A921
N07CA01
NINDS_000602
2-(2-methylamino-ethyl)-pyridine
HMS3886O12
BCP16849
HY-B0524
Methyl-(2-pyridin-2-ylethyl)amine
N-methyl-2-pyridin-2-ylethaneamine
NSC42617
AKOS BBS-00002883
2-[2-(N-methylamino)ethyl]pyridine
AR1013
BBL004908
methyl-(2-pyridin-2-yl-ethyl)amine
s5619
STK801447
AKOS000255727
N-methyl-2-(pyridine-2-yl)ethanamine
2-(2-Methylaminoethyl)pyridine, 97%
CCG-266132
DB06698
N-Methyl-2-(2-pyridinyl)ethanamine #
PS-4217
SB17406
SB37365
IDI1_000602
NCGC00093362-02
NCGC00093362-03
SMR000059096
SBI-0051588.P003
DB-052905
AB00053577
CS-0009496
NS00006018
EN300-17834
D07522
methyl-[2-(2-pyridyl)ethyl]amine;hydrochloride
AB00053577_12
AB00053577_13
N-methyl-2-(2-pyridinyl)ethanamine;hydrochloride
N-methyl-2-pyridin-2-yl-ethanamine;hydrochloride
Q368995
BRD-K91315211-300-02-4
BRD-K91315211-300-05-7
BRD-K91315211-300-06-5
BRD-K91315211-334-02-3
F2158-0901
227-086-4