Interesting facts
Exploring N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide
N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide is an intriguing compound that has garnered attention for its potential applications in the field of pharmacology. Here are some captivating insights:
- Pharmacological Potential: This compound is associated with the modulation of psychiatric and neurological disorders. Its unique structure, which combines the indole and piperidine moieties, allows it to interact selectively with various neurotransmitter systems.
- Cognitive Enhancer: It has been studied for its possible use as a cognitive enhancer, showing promise in improving memory and learning processes. As research continues, it may offer new avenues for treating conditions such as Alzheimer’s disease or schizophrenia.
- Diverse Applications: Beyond its neurological implications, researchers are investigating its use in other areas, such as oncology and pain management. The compound's sulfonamide group is particularly noteworthy as it can contribute to anti-inflammatory properties.
- Synthetic Challenges: The synthesis of this compound poses several intriguing challenges due to its complex structure. Chemists must navigate delicate reaction conditions and purification processes, making it a compelling subject for students and researchers alike.
- Interdisciplinary Connections: N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide exemplifies the intersection of organic chemistry and medicinal research. It highlights the importance of understanding chemical interactions and molecular design, essential for drug development.
In summary, N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide represents a fascinating area of study, where chemistry meets the pursuit of novel therapeutic agents. Its diverse possibilities underscore the dynamic nature of compound research in paving the way for medical advancements.
Synonyms
naratriptan
121679-13-8
N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide
Naramig
1H-Indole-5-ethanesulfonamide, N-methyl-3-(1-methyl-4-piperidinyl)-
naratriptanum
N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide
UNII-QX3KXL1ZA2
QX3KXL1ZA2
Naratriptan (INN)
CHEBI:7478
CHEMBL1278
N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide
DTXSID7023354
N-Methyl-2-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)ethanesulfonamide
Colatan
NARATRIPTAN [INN]
N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethane-1-sulfonamide
Naramig (TN)
NCGC00181786-01
Naratriptan [INN:BAN]
N-methyl-2-(3-(1-methyl-4-piperidyl)-1H-indol-5-yl)-ethanesulfonamide
NARATRIPTAN [MI]
GTPL45
NARATRIPTAN [VANDF]
SCHEMBL68753
NARATRIPTAN [WHO-DD]
BIDD:GT0312
DTXCID003354
N02CC02
NARATRIPTAN [ORANGE BOOK]
HY-B0197
BDBM50073682
N-methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide
AKOS015895854
AC-5013
BCP9000978
DB00952
NCGC00181786-03
NCGC00181786-04
NCGC00181786-08
FN170148
TS-09866
NS00006374
C07792
D08255
G78311
AB01565792_02
EN300-18567334
L000432
Q421315
BRD-K61337602-003-02-1
BRD-K61337602-003-03-9
N-Methyl-3-(1-methyl-4 -piperidinyl)-1H-indole-5-ethansulphonamide
N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulphonamide
2-[3-(1-Methyl-piperidin-4-yl)-1H-indol-5-yl]-ethanesulfonic acid methylamide
InChI=1/C17H25N3O2S/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14/h3-4,11-12,14,18-19H,5-10H2,1-2H
Naratriptan; 1H-Indole-5-ethanesulfonamide, N-methyl-3-(1-methyl-4-piperidinyl)-; N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide; N-Methyl-3-(1-methyl-4-piperidyl)indole-5-ethanesulfonamide; Naratriptan
Solubility of N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide
The solubility of a compound can significantly influence its application and effectiveness, particularly in pharmaceutical and chemical processes. In the case of N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide (C18H26N2O2S), the following points are noteworthy:
Research or experimental data would be essential to determine the exact solubility parameters, but understanding these structural aspects is critical. As a general rule, compounds like this one that feature both hydrophobic and hydrophilic regions often display amphiphilic behavior, which can impact their bioavailability and interactions in biological systems.
Ultimately, the solubility profile will play a vital role in the pharmacokinetics and therapeutic efficacy of N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide, making it a topic of significant interest in further research and development.