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5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT)

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Identification
Molecular formula
C14H19NS2
CAS number
1019-45-0
IUPAC name
N-methyl-2-(5-methylsulfanyl-1H-indol-3-yl)propan-1-amine
State
State

At room temperature, 5-MeO-DMT is typically found in a solid-state, often as a powder.

Melting point (Celsius)
69.00
Melting point (Kelvin)
342.15
Boiling point (Celsius)
137.10
Boiling point (Kelvin)
410.20
General information
Molecular weight
246.36g/mol
Molar mass
246.3620g/mol
Density
1.2300g/cm3
Appearence

5-MeO-DMT appears as a crystalline powder. It may present itself in various colors, ranging from white to a light yellow or beige color, due to impurities. The compound is usually finely granulated or formed in small crystalline structures.

Comment on solubility

Solubility of N-methyl-2-(5-methylsulfanyl-1H-indol-3-yl)propan-1-amine

N-methyl-2-(5-methylsulfanyl-1H-indol-3-yl)propan-1-amine exhibits solubility characteristics that can be intriguing due to its structural features.

Several factors influence the solubility of this compound:

  • Polarity: The presence of the amine functional group typically contributes to a certain level of polarity, which can enhance solubility in polar solvents such as water.
  • Hydrophobic regions: The indole structure introduces hydrophobic character, which may limit solubility in purely aqueous environments.
  • Bulkiness: The steric hindrance from the methyl groups could potentially affect how well this compound interacts with solvent molecules.
  • Hydrogen bonding: The ability of the amine group to form hydrogen bonds can enhance solubility in specific solvents.

In practice, solubility is often assessed under various conditions, and the results may differ significantly based on:

  1. Temperature: Increased temperature may improve solubility for some compounds.
  2. pH levels: The ionization state of the amine can vary with pH, altering solubility.
  3. Presence of co-solvents: Using mixtures of solvents can enhance solubility by providing a better environment for dissolution.

Ultimately, understanding the solubility of N-methyl-2-(5-methylsulfanyl-1H-indol-3-yl)propan-1-amine is crucial for applications in fields such as pharmaceuticals, where solubility can greatly affect bioavailability and therapeutic effectiveness.

Interesting facts

Exploring N-methyl-2-(5-methylsulfanyl-1H-indol-3-yl)propan-1-amine

N-methyl-2-(5-methylsulfanyl-1H-indol-3-yl)propan-1-amine is a fascinating compound that has drawn the interest of researchers due to its unique structural features and the potential applications in various fields.

Interesting Aspects of the Compound

  • Structural Diversity: The presence of the indole ring, which is a common motif in many biologically active compounds, adds intricate chemical properties to this compound. This ring structure is known for its role in neurotransmitter functioning and can contribute to its activity in biological systems.
  • Biological Significance: Compounds containing indole derivatives have been associated with various physiological effects including antidepressant and antimicrobial properties, making this compound worthy of investigation in the pharmacological realm.
  • Methylsulfanyl Group: The 5-methylsulfanyl group on the indole ring offers additional reactivity and may lend itself to interesting interactions with biological targets, possibly enhancing the compound's bioactivity.
  • Synthesis Routes: Researchers are continually developing novel synthetic pathways for creating compounds like this one, often employing techniques such as cross-coupling reactions and amine alkylation to obtain high yields with specific stereochemistry.
  • Potential Aromatic Activity: Aromatic amines, like this compound, are vital in synthetic chemistry and are frequently used in the production of pharmaceuticals, dyes, and agrochemicals.

As scientists continue to uncover the properties and applications of N-methyl-2-(5-methylsulfanyl-1H-indol-3-yl)propan-1-amine, it stands to represent the intersection of medicinal chemistry and synthetic innovation. The exploration of its biological activity can open doors for new therapeutic agents, showcasing the importance of such compounds in modern materials science.

Synonyms
BRN 0397146
INDOLE, 3-(1-METHYLAMINO-2-PROPYL)-5-METHYLTHIO-
3-(Methylaminopropyl-2')-5-methylthioindole
5564-15-8
5-22-12-00092 (beilstein handbook reference)
DTXSID10970982
N-Methyl-2-[5-(methylsulfanyl)-1H-indol-3-yl]propan-1-amine