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Methamphetamine

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Identification
Molecular formula
C10H15N
CAS number
537-46-2
IUPAC name
N-methyl-2-[o-tolyl(phenyl)methoxy]ethanamine
State
State

Methamphetamine is typically found in crystalline powder form at room temperature.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
215.00
Boiling point (Kelvin)
488.15
General information
Molecular weight
149.23g/mol
Molar mass
149.2330g/mol
Density
0.9130g/cm3
Appearence

Methamphetamine is a colorless volatile liquid. In its solid form, it appears as a white, odorless crystalline powder. It is soluble in alcohol, chloroform, and water.

Comment on solubility

Solubility of N-methyl-2-[o-tolyl(phenyl)methoxy]ethanamine

N-methyl-2-[o-tolyl(phenyl)methoxy]ethanamine, a compound with intriguing structural characteristics, demonstrates unique solubility properties. When discussing the solubility of this compound, consider the following points:

  • Polarity: The presence of the methoxy group suggests some degree of polarity which may contribute to its solubility in polar solvents.
  • Functional Groups: The o-tolyl and phenyl groups can influence solubility through hydrophobic interactions, potentially making it less soluble in water but more so in organic solvents.
  • Solvent Interaction: The compound is likely to be soluble in organic solvents like ethanol, methanol, or dimethyl sulfoxide (DMSO), while exhibiting limited solubility in water.
  • Temperature Effects: Like many organic compounds, its solubility may increase with temperature, enhancing interactions with solvents.

In summary, while N-methyl-2-[o-tolyl(phenyl)methoxy]ethanamine has the potential to dissolve effectively in certain organic environments, its hydrophobic components may hinder water solubility. As a general rule, it is wise to perform solubility tests under varied conditions to fully understand its behavior in different mediums.

Interesting facts

Interesting Facts about N-methyl-2-[o-tolyl(phenyl)methoxy]ethanamine

N-methyl-2-[o-tolyl(phenyl)methoxy]ethanamine is a fascinating compound with intriguing properties and potential applications. Here are some key points to consider:

  • Origin of Name: The name of this compound reflects its structure. The "N-methyl" indicates a methyl group attached to a nitrogen atom, while "o-tolyl" and "phenyl" suggest the presence of aromatic rings, which are often associated with stability and reactivity.
  • Synthetic Pathways: This compound can be synthesized through various methods, involving reactions that typically include amination techniques. Chemists often explore various synthetic routes to optimize yields and minimize by-products.
  • Biological Significance: Compounds of this nature may exhibit biological activity, making them of interest in medicinal chemistry. Understanding how the different functional groups interact with biological systems can lead to the discovery of new pharmaceuticals.
  • Uses in Research: As a compound with both amine and ether functionalities, it may serve as a versatile building block in organic synthesis, enabling the creation of more complex molecules in drug development.
  • Structural Features: The aromatic sections of the molecule can provide enhanced electronic properties, making them suitable for various applications, including as ligands in coordination chemistry.
  • Chemical Behavior: Its unique structure may impart characteristics such as specific reactivity patterns or solubility traits, making it an interesting subject for kinetic and mechanism studies.

In summary, N-methyl-2-[o-tolyl(phenyl)methoxy]ethanamine represents a rich area of study within organic and medicinal chemistry, inviting further exploration into its properties and applications. As one delves deeper into the realm of this compound, one might find the relationship between its structure and function particularly enlightening.

Synonyms
TOFENACIN
Tofenacine
15301-93-6
demethylorphenadrine
Tofenacina
Elamol
Nororphenadrine
Tofenacin, (+)-
Tofenacin, (-)-
N-methyl-2-[(2-methylphenyl)-phenylmethoxy]ethanamine
WV5MS5T7YD
D67B6M43WW
C4A112M10H
J8.547B
Ethanamine, N-methyl-2-((2-methylphenyl)phenylmethoxy)-
Ethanamine, N-methyl-2-[(2-methylphenyl)phenylmethoxy]-
Tofenacinum
33431-04-8
33431-05-9
NSC113809
NSC169432
Tofenacin [INN:BAN]
Tofenacine [INN-French]
Tofenacinum [INN-Latin]
Tofenacina [INN-Spanish]
N-Methyl-2-[(o-methyl-.alpha.-phenylbenzyl)oxy]ethylamine
UNII-C4A112M10H
N-METHYL-2-((O-METHYL-.ALPHA.-PHENYLBENZYL)OXY)ETHYLAMINE
N-(Methylamino)ethyl 2-methylbenzhydryl ether hydrochloride
EINECS 239-338-0
Phenyl-(o-tolylmethyl) (methylamino)ethyl ether hydrochloride
Tofenacin (free base)
N-Demethyl orphenadrine
TOFENACIN [INN]
TOFENACIN [MI]
UNII-WV5MS5T7YD
TOFENACIN [WHO-DD]
UNII-D67B6M43WW
SCHEMBL49290
CHEMBL2110923
DTXSID50864578
CHEBI:135046
NS00051629
N-methyl-2-[o-tolyl(phenyl)methoxy]ethanamine
Q7812962
N-methyl-2-[(o-methyl-a-phenylbenzyl)oxy]-ethylamine
N-Methyl-2-((2-methylphenyl)(phenyl)methoxy)ethanamine
{[2-(Phenyl-o-tolylmethoxy)ethyl]methylamine} hydrochloride
N-Methyl-2-[(2-methylphenyl)(phenyl)methoxy]ethan-1-amine
N-Methyl-2-[(2-methylphenyl)(phenyl)methoxy]ethanamine #
N-Methyl-N-(2-((2-methylphenyl)(phenyl)methoxy)ethyl)amine
{N-Methyl-2-[.alpha.-(2-tolylbenzyl)oxy]ethylamine} hydrochloride
Ethylamine, N-methyl-2-((O-methyl-alpha-phenylbenzyl)oxy)-, (+)-
Ethylamine, N-methyl-2-((O-methyl-alpha-phenylbenzyl)oxy)-, (-)-
{N-Methyl-2-[(o-methyl-.alpha.-phenylbenzyl)oxy]ethylamine} hydrochloride
Ethanamine, {N-methyl-2-[(2-methylphenyl)phenylmethoxy]-,} hydrochloride
Ethylamine, {N-methyl-2-[(o-methyl-.alpha.-phenylbenzyl)oxy]-,} hydrochloride
ETHYLAMINE, N-METHYL-2-((O-METHYL-.ALPHA.-PHENYLBENZYL)OXY)-, (+)-
ETHYLAMINE, N-METHYL-2-((O-METHYL-.ALPHA.-PHENYLBENZYL)OXY)-, (-)-