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Methamphetamine

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Identification
Molecular formula
C10H15N
CAS number
51-57-0
IUPAC name
N-methyl-2-phenyl-propan-1-amine
State
State

At room temperature, methamphetamine is typically found in a crystalline solid state, which can be dissolved in water for liquid usage.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
215.00
Boiling point (Kelvin)
488.15
General information
Molecular weight
149.23g/mol
Molar mass
149.2330g/mol
Density
0.9112g/cm3
Appearence

Methamphetamine typically appears as a white, crystalline powder, but it can also appear as a pill or a shiny, bluish-white rock type known as crystal meth. As a powder, it is bitter-tasting and odorless.

Comment on solubility

Solubility of N-methyl-2-phenyl-propan-1-amine

N-methyl-2-phenyl-propan-1-amine, also known as methamphetamine, exhibits notable solubility characteristics influenced by its chemical structure. It is important to consider several factors when discussing its solubility:

  • Polarity: The presence of an amine functional group contributes to the polar nature of this compound, enhancing its solubility in polar solvents.
  • Solvation: N-methyl-2-phenyl-propan-1-amine tends to dissolve well in water as well as organic solvents, such as ethanol and acetone, due to its amphipathic nature.
  • Temperature Effects: Like many organic compounds, solubility can increase with temperature. Thus, heating the solvent may enhance the solubility of N-methyl-2-phenyl-propan-1-amine.

Moreover, it is crucial to note that the pH of the solution can significantly affect solubility attributes. In acidic conditions, the compound may exist predominantly in its protonated form, which could lead to higher solubility in aqueous solutions. In contrast, under neutral or basic conditions, the solubility might decrease as the compound becomes less stable in water.

In summary, the solubility of N-methyl-2-phenyl-propan-1-amine is influenced by its chemical composition, polarity, temperature, and the pH of the solution, making it an interesting compound to study in various chemical environments.

Interesting facts

Exploring N-methyl-2-phenyl-propan-1-amine

N-methyl-2-phenyl-propan-1-amine, often known as an aromatic amine, has garnered attention in various fields of chemistry due to its unique properties and applications. Here are some fascinating facts about this compound:

  • Structure and Isomerism: This compound features a chiral center, making it an interesting subject for the study of stereochemistry. Isomers can exhibit significantly different biological activities, highlighting the importance of three-dimensional arrangement in molecular interactions.
  • Biological Significance: Compounds structurally related to N-methyl-2-phenyl-propan-1-amine have been investigated for their role in pharmacology. They may exhibit stimulant properties, which has implications for research into focused cognitive enhancement and mood elevation.
  • Applications: This compound serves as a precursor in the synthesis of various pharmaceuticals, including antidepressants and weight control agents. Understanding its reactivity can lead to the development of more effective therapeutic agents.
  • Psychoactive Research: Due to its structural resemblance to certain psychoactive substances, it opens avenues for research into neurotransmitter activity and receptor interactions, which might lead to treatments for conditions such as depression and ADHD.
  • Synthetic Pathways: Chemists are exploring innovative synthetic routes to create N-methyl-2-phenyl-propan-1-amine with high enantiomeric purity, which is essential for maximizing efficacy and minimizing side effects in pharmaceuticals.

In summary, N-methyl-2-phenyl-propan-1-amine not only fascinates with its structural features but also carries potential in medicinal chemistry and therapeutic applications. Its role as a building block in drug development continues to inspire researchers looking for novel treatments and better understanding of biochemical pathways.

Synonyms
PHENPROMETHAMINE
Phenpromethaminum
93-88-9
Vonedrine
Fenprometamina
methyl(2-phenylpropyl)amine
N-Methyl-2-phenylpropylamine
Phenpromethadrinum
1-Methylamino-2-phenylpropane
Phenpromethadrine
N,beta-Dimethylphenethylamine
Phenpromethamine [INN:DCF]
Fenprometamina [INN-Spanish]
1-Methylamino-2-methyl-2-phenylethane
Phenpromethaminum [INN-Latin]
Dl-n-methyl-2-phenylpropylamine
1-Phenyl-1-methyl-2-methylaminoethane
7D4542I59V
BRN 3196526
1-Phenyl-1-methyl-2-methylamino-aethan
PHENPROMETHAMINE [INN]
PHENPROMETHAMINE [MART.]
Phenethylamine, N,beta-dimethyl-
1-Phenyl-1-methyl-2-methylamino-aethan [German]
3-12-00-02689 (Beilstein Handbook Reference)
Benzeneethanamine, N,beta-dimethyl-
PHENYLPROPYLMETHYLAMINE [MI]
N,.BETA.-DIMETHYLPHENETHYLAMINE
N,.BETA.-DIMETHYLBENZENEETHANAMINE
PHENETHYLAMINE, N,.BETA.-DIMETHYL-
DL-N,.BETA.-DIMETHYLBENZENEETHANAMINE
BENZENEETHANAMINE, N,.BETA.-DIMETHYL-
Fenprometamina (INN-Spanish)
Phenpromethaminum (INN-Latin)
PHENPROMETHAMINE (MART.)
N,beta-Dimethylbenzeneethanamine
Benzeneethanamine, N,beta-dimethyl-(9CI)
DL-N,BETA-DIMETHYLBENZENEETHANAMINE
(+-)-1-METHYLAMINO-2-PHENYLPROPANE
823-163-7
phenylpropylmethylamine
Methyl-(2-phenyl-propyl)-amine
N-methyl-2-phenylpropan-1-amine
Phenpromethamin
MLS000708563
SMR000289130
UNII-7D4542I59V
cid_22275
SCHEMBL681384
CHEMBL1622886
BDBM96687
DTXSID20861690
N-Methyl-2-phenyl-1-propylamine
AUFSOOYCQYDGES-UHFFFAOYSA-N
CHEBI:134771
N-Methyl-beta-Methylphenethylamine
HMS1691M02
AAA09388
STK511146
AKOS000302817
AKOS017269518
methyl(2-phenylpropyl)amine;hydrochloride
NCGC00245147-01
benzene, (1-methyl-2-methylamino)ethyl-
methyl-(2-phenyl-propyl)-amine, AldrichCPR
NS00001594
(+/-)-1-METHYLAMINO-2-PHENYLPROPANE
EN300-66712
N-methyl-2-phenyl-1-propanamine;hydrochloride
N-methyl-2-phenyl-propan-1-amine;hydrochloride
Q7181405
Z57797325