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Methamphetamine hydrochloride

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Identification
Molecular formula
C10H16ClN
CAS number
51-57-0
IUPAC name
N-methyl-2-phenyl-propan-1-amine;hydrochloride
State
State

Methamphetamine hydrochloride is typically found in a solid state at room temperature, usually appearing as crystalline solids. It is primarily known and utilized as a psychoactive drug, though it is also used medicinally under strict regulation.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
185.71g/mol
Molar mass
185.7050g/mol
Density
1.0000g/cm3
Appearence

The compound typically appears as a white crystalline powder or as clear crystals. In its pure state, it is almost odorless. It is often sold in the illegal drug market with a variety of impurities, which can alter its appearance.

Comment on solubility

Solubility of N-methyl-2-phenyl-propan-1-amine;hydrochloride

N-methyl-2-phenyl-propan-1-amine;hydrochloride, often referred to as a salt form, exhibits specific solubility characteristics that are crucial for its application in various chemical processes. As an amine hydrochloride, it tends to be highly soluble in aqueous solutions due to the ionic interaction between the amine and the chloride ion.

Key points regarding its solubility include:

  • High Aqueous Solubility: The presence of the hydrochloride form greatly enhances solubility in water, making it easier to handle and incorporate into solutions.
  • Solvents: It is also soluble in other polar solvents, although less so in non-polar solvents, which is common for amines and their salts.
  • Temperature Effects: Increased temperature generally improves solubility, which is an important factor in preparation and reaction conditions.
  • pH Dependence: The solubility can be influenced by the pH of the solution, with notable variations observed under different acidity conditions.

In conclusion, the solubility profile of N-methyl-2-phenyl-propan-1-amine;hydrochloride is characterized by strong solubility in water and other polar solvents, which supports its wide utility in both research and pharmaceutical applications. Understanding these solubility characteristics can significantly affect its functional use in various chemical reactions and formulations.

Interesting facts

Interesting Facts about N-methyl-2-phenyl-propan-1-amine Hydrochloride

N-methyl-2-phenyl-propan-1-amine hydrochloride, commonly referred to in scientific literature and research, is a fascinating organic compound that falls under the category of substituted amphetamines. Here are some compelling insights:

  • Structural Significance: This compound features a phenyl group attached to a carbon chain, giving it a unique structure that is significant in both medicinal chemistry and pharmacology. The addition of a methyl group enhances its lipophilicity, which is essential for its biological activity.
  • Medicinal Applications: N-methyl-2-phenyl-propan-1-amine has been explored for its potential use as a stimulant and has applications in the treatment of various disorders, including attention deficit hyperactivity disorder (ADHD) and narcolepsy.
  • Mechanism of Action: As a compound that interacts with neurotransmitter systems, it is known to increase the release of dopamine and norepinephrine, contributing to its stimulant effects. This action makes it a subject of interest for studies on addiction and dependency.
  • Synthesis Interests: The synthesis of N-methyl-2-phenyl-propan-1-amine hydrochloride involves several chemical transformations that are of interest to synthetic chemists, including amination and alkylation reactions, showcasing the beauty of organic synthesis.
  • Research Perspectives: Current research is not only focused on the therapeutic uses of this compound but also on its social implications and the ongoing discussions regarding its classification and regulation due to its potential for abuse.

In summary, N-methyl-2-phenyl-propan-1-amine hydrochloride embodies a rich tapestry of chemical properties and societal relevance, making it a noteworthy subject in both academic and clinical settings. Its engaging history and application underline the complexities of drug design and development in the field of modern chemistry.

Synonyms
5969-39-1
N,beta-Dimethylphenethylamine hydrochloride
PHENPROMETHAMINE HYDROCHLORIDE
Phenylpropylmethylamine Hydrochloride
Methyl-(2-phenyl-propyl)-amine hydrochloride
N-methyl-2-phenylpropan-1-amine;hydrochloride
NIOSH/SH5465000
91L40I3N18
Vonedrine hydrochloride
SH54650000
dl-beta-Phenyl-n-propylmethylamine hydrochloride
(+-)-N,beta-Dimethylphenethylamine hydrochloride
N-Methyl-beta-Methylphenylethylamine hydrochloride
Phenethylamine, N,beta-dimethyl-, hydrochloride, (+-)-
MLS000708563
N-Methyl-2-phenylpropan-1-amine HCl
SMR000289130
UNII-91L40I3N18
Phenethylamine, N,beta-dimethyl-, hydrochloride
N-methyl beta-methylphenylethylamine HCL
N-Methyl-2-phenylpropylamine hydrochloride
PHENPROMETHAMINE HCL
Phenethylamine, N,.beta.-dimethyl-, hydrochloride
Benzeneethanamine, N,.beta.-dimethyl-, hydrochloride
SCHEMBL6235704
CHEMBL1479941
DTXSID20975089
PHENYLPROPYLMETHYLAMINE HCL
AKOS015846355
FP27003
HY-W354635
PD017356
N-Methyl-2-phenylpropan-1-amine (hydrochloride)
1-METHYLAMINO-2-PHENYLPROPANE HYDROCHLORIDE
Q27271409
N-Methyl-2-phenylpropan-1-amine--hydrogen chloride (1/1)
BENZENEETHANAMINE, N,.BETA.-DIMETHYL-, HYDROCHLORIDE (1:1)
N,b-Dimethylbenzeneethanamine hydrochloride;N,b-Dimethylphenethylamine hydrochloride;1-Methylamino-2-methyl-2-phenylethane hydrochlo ride;N-Methyl-?-methylphenylethylamine hydrochloride