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Methamphetamine

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Identification
Molecular formula
C10H15N
CAS number
537-46-2
IUPAC name
N-methyl-3-(1-phenyl-3H-2-benzothiophen-1-yl)propan-1-amine
State
State

Methamphetamine is typically found in a solid state at room temperature. However, depending on its form and purity, it can also be encountered as a liquid or gas in various illicit preparations or during synthesis.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
215.60
Boiling point (Kelvin)
488.80
General information
Molecular weight
149.23g/mol
Molar mass
149.2330g/mol
Density
1.0900g/cm3
Appearence

The compound typically appears as a white crystalline substance. It is known for its glassy, shard-like crystalline texture, which can range in appearance from fine powder to larger, chunky crystals. The appearance may vary slightly depending on purity and synthesis methods.

Comment on solubility

Solubility of N-methyl-3-(1-phenyl-3H-2-benzothiophen-1-yl)propan-1-amine

N-methyl-3-(1-phenyl-3H-2-benzothiophen-1-yl)propan-1-amine, a complex organic compound, presents intriguing solubility characteristics.

Understanding its solubility involves considering several key factors:

  • Polarity: The presence of polar amine groups may enhance solubility in polar solvents, while the aromatic and thiophene components could increase lipophilicity, favoring solubility in nonpolar solvents.
  • Hydrogen Bonding: The ability of the amine to engage in hydrogen bonding can facilitate solubility in water, though the overall structure might still hinder extensive solvation.
  • Solvent Selection: It is likely to be more soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and acetone, while showing limited solubility in water.

In practice, solubility tests may reveal that while it dissolves to some extent in aqueous environments, it does not achieve high solubility levels, which may be attributed to the bulky, hydrophobic aromatic structure. This makes predicting its behavior in pharmaceutical applications particularly interesting.

To summarize:

  • Moderately soluble in polar solvents
  • Better solubility in organic solvents
  • Potential for limited aqueous solubility due to structural hindrances

Overall, the solubility behavior of this compound can be described as complex and dependent on environmental conditions, reflecting both its unique molecular architecture and functional groups.

Interesting facts

Interesting Facts about N-methyl-3-(1-phenyl-3H-2-benzothiophen-1-yl)propan-1-amine

N-methyl-3-(1-phenyl-3H-2-benzothiophen-1-yl)propan-1-amine is a fascinating compound that merges the fields of organic chemistry and pharmacology. Here are some intriguing aspects of this compound:

  • Structural Complexity: This compound features an intricate structure, including a benzothiophene moiety. The combination of the benzene and thiophene rings contributes to its unique chemical properties.
  • Psychoactive Potential: Compounds like N-methyl-3-(1-phenyl-3H-2-benzothiophen-1-yl)propan-1-amine are often researched for their psychoactive effects. The amine group may play a crucial role in its interaction with neuroreceptor pathways.
  • Research Applications: This compound could be of interest in the development of pharmaceuticals, particularly in the realm of mental health, due to its potential as a neurotransmitter modulator.
  • Analog Studies: Scientists are known to create analogs of this compound to enhance its properties, studying modifications to improve efficacy and reduce side effects.

In the words of researchers, "Understanding the structure-activity relationship of compounds like this can lead to groundbreaking advancements in therapy for various psychological disorders."
The exploration of such compounds adds depth to our knowledge in medicinal chemistry and offers prospects for innovative treatments.

Furthermore, the continuing study of N-methyl-3-(1-phenyl-3H-2-benzothiophen-1-yl)propan-1-amine provides rich avenues for research in both organic synthesis and biological activity, making it a compound of significant importance in contemporary chemistry.