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Amitriptyline

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Identification
Molecular formula
C20H23N
CAS number
549-18-8
IUPAC name
N-methyl-3-(2-methyl-6H-benzo[c][1]benzothiepin-11-ylidene)propan-1-amine
State
State

Amitriptyline is a solid at room temperature. It is most commonly encountered in its salt form as amitriptyline hydrochloride for pharmaceutical use.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
408.35
Boiling point (Kelvin)
681.50
General information
Molecular weight
277.40g/mol
Molar mass
277.4040g/mol
Density
1.0300g/cm3
Appearence

Amitriptyline is typically encountered as its hydrochloride salt, appearing as a white or off-white powder. It is crystalline in nature and can sometimes appear as a fine powder.

Comment on solubility

Solubility of N-methyl-3-(2-methyl-6H-benzo[c][1]benzothiepin-11-ylidene)propan-1-amine

The solubility of N-methyl-3-(2-methyl-6H-benzo[1]benzothiepin-11-ylidene)propan-1-amine is an interesting aspect to consider, as it influences both its chemical behavior and practical applications. This compound is part of a class of organic molecules that can exhibit varying solubility based on several factors:

  • Polarity: The molecular structure of this compound contains both non-polar (aromatic rings) and polar (amine group) components, which can lead to limited solubility in water but potentially high solubility in organic solvents.
  • Temperature: Like many organic compounds, an increase in temperature may enhance solubility, allowing for better dissolution in appropriate solvent systems.
  • pH Levels: The presence of an amine functional group suggests that the solubility can be affected by the pH of the solution; in acidic conditions, the amine group can become protonated, increasing solubility in aqueous environments.

As a general rule, "like dissolves like." This implies that:

  • If the compound is placed in a non-polar solvent (e.g., hexane), solubility may be higher.
  • In contrast, aqueous solutions could present challenges due to its structural characteristics.

In conclusion, the solubility behavior of N-methyl-3-(2-methyl-6H-benzo[1]benzothiepin-11-ylidene)propan-1-amine is quite complex, dictated by its unique molecular features and external conditions. Understanding these factors is crucial for applications in pharmaceuticals and materials science.

Interesting facts

Interesting Facts about N-methyl-3-(2-methyl-6H-benzo[c][1]benzothiepin-11-ylidene)propan-1-amine

N-methyl-3-(2-methyl-6H-benzo[1]benzothiepin-11-ylidene)propan-1-amine is a fascinating compound that belongs to a group of chemicals known for their unique structures and potential applications. Here are some intriguing aspects of this compound:

  • Structure Complexity: This compound features a complex and unique molecular structure that incorporates a benzo[b]thiepin core, which is significant in various biological activities.
  • Potential Pharmacological Applications: Compounds like these have gained attention for their potential therapeutic effects, particularly in the fields of psychiatry and neuropharmacology. Many molecules with similar frameworks have shown promise for treating disorders such as schizophrenia and depression.
  • Research Interest: Its distinct features have led to increased research interest to explore its interaction with neuroreceptors and to evaluate its efficacy in drug formulations. Scientists aim to uncover its action mechanism at a molecular level.
  • Synthetic Routes: The synthesis of such complex organic structures often involves intricate and multi-step chemical processes, which can be a thrilling challenge for chemists and students alike. Learning the methods of constructing these compounds enhances critical thinking and problem-solving skills in organic synthesis.
  • Chemical Properties and Reactions: The compound may exhibit unique chemical properties that can lead to interesting reactivity. Understanding its behavior under various conditions could unveil opportunities for creating more efficient synthetic pathways or applications in medicinal chemistry.

This compound exemplifies the intersection between organic chemistry and pharmacology, showcasing how intricate molecular designs can lead to groundbreaking discoveries in medicine. As research continues, it may pave the way for new therapeutic strategies that could impact healthcare significantly.