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clomipramine hydrochloride

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Identification
Molecular formula
C19H24ClN
CAS number
303-49-1
IUPAC name
N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine;hydrochloride
State
State
At room temperature, clomipramine hydrochloride is typically in a solid state as a crystalline powder.
Melting point (Celsius)
193.00
Melting point (Kelvin)
466.15
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.15
General information
Molecular weight
351.86g/mol
Molar mass
351.8640g/mol
Density
1.1600g/cm3
Appearence

Clomipramine hydrochloride appears as a white to off-white crystalline powder. It is sparingly soluble in water and has a slight, distinctive odor.

Comment on solubility

Solubility of N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine;hydrochloride

The solubility of N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine;hydrochloride can be quite intriguing due to its complex molecular structure. There are several factors that influence the solubility of this compound:

  • Ionic Nature: As a hydrochloride salt, this compound is likely to be more soluble in polar solvents, such as water, compared to its parent amine.
  • Hydrogen Bonding: The presence of functional groups capable of forming hydrogen bonds can enhance solubility in aqueous solutions.
  • Molecular Size: Its large and complex tricyclic structure can impede solubility due to steric hindrance.
  • pH Dependency: The solubility may vary significantly with changes in pH, affecting the ionization of the amino group.

In consideration of these factors, it’s critical to understand that the solubility characteristics of this compound are not simply a function of its ionic and polar nature, but also involve intricate interactions with the solvent system. Although one might expect a good level of solubility due to its hydrochloride form, the actual dissolution behavior may necessitate experimental verification in specific conditions.

Interesting facts

Interesting Facts about N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine; hydrochloride

This unique compound, often denoted as a hydrochloride salt, features a complex structure that makes it an intriguing subject for both chemists and researchers interested in organic chemistry. Below are several key aspects that highlight its significance:

  • Structural Complexity: The compound incorporates a tricyclic component along with a heptaene subsystem, which plays a crucial role in its chemical properties and potential applications.
  • Pharmacological Potential: Compounds with similar structural motifs have been explored for their biological activities, including potential applications in medicinal chemistry. Understanding this compound's interactions could yield insights into its therapeutic properties.
  • Synthetic Challenges: The synthesis of such intricate molecules involves advanced organic synthesis techniques. Researchers often encounter hurdles related to selectivity and yield, making the study of this compound a valuable learning experience for students.
  • Isomerism: Due to its complex framework, this compound may exhibit various isomeric forms, each potentially differing in physical and chemical properties. This opens up discussions on stereochemistry and its implications in biological systems.
  • Material Science Applications: The unique properties of the tricyclic structures in this compound may position it for use in novel materials, including polymers or catalysts, paving the way for innovative advancements in material science.

As noted by notable chemists, "Understanding the intricacies of complex organic compounds can lead to revolutionary breakthroughs in chemistry and related fields." The exploration of N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine; hydrochloride is a prime example of how delving into the molecular world can inspire future discoveries.

Synonyms
438-59-5
Desmethyl Cyclobenzaprine Hydrochloride
Ro 4-6011
3-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)propyl(methyl)ammonium chloride
10,11-Didehydronortriptyline Hydrochloride
1-Propanamine,3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-,hydrochloride (1:1)
N 7068 hydrochloride
N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine;hydrochloride
3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)propyl(methyl)ammonium chloride
1-Propanamine, 3-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methyl-, hydrochloride
3-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine hydrochloride
EINECS 207-118-3
Desmethylcyclobenzaprine HCl
Norproheptatriene Hydrochloride
1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-, hydrochloride
Desmethylcyclobenzaprine hydrochloride
VKZ2UCW7RG
3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamin hydrochloride
3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine Hydrochloride
5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, N-methyl-, hydrochloride
Norcyclobenzaprine Hydrochloride
DTXSID70963118
UZMPCPFDZYTEJG-UHFFFAOYSA-N
AKOS030242111
Cyclobenzaprine related compound B [USP IMPURITY]
1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-, hydrochloride (1:1)
3-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine--hydrogen chloride (1/1)
3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, hydrochloride
5H-Dibenzo[a,d]cycloheptene-Delta5,gamma-propylamine, N-methyl-, hydrochloride
207-118-3
3-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine Hydrochloride (Norcyclobenzaprine Hydrochloride)
3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine hydrochloride;10,11-Didehydronortriptyline hydrochloride;N 7068 hydr ochloride
N-Desmethylcyclobenzaprine Hydrochloride (Norcyclobenzaprine Hydrochloride) 1.0 mg/ml in Methanol (as free base)