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Memantine

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Identification
Molecular formula
C12H21N
CAS number
19982-08-2
IUPAC name
N-methyl-3-[3-(methylamino)-1-adamantyl]adamantan-1-amine
State
State

At room temperature, Memantine is a solid in the form of a crystalline powder.

Melting point (Celsius)
292.00
Melting point (Kelvin)
565.15
Boiling point (Celsius)
381.46
Boiling point (Kelvin)
654.61
General information
Molecular weight
215.36g/mol
Molar mass
215.3630g/mol
Density
1.4500g/cm3
Appearence

Memantine appears as a white to off-white crystalline powder. It is practically insoluble in water, slightly soluble in ethanol and soluble in methanol.

Comment on solubility

Solubility of N-methyl-3-[3-(methylamino)-1-adamantyl]adamantan-1-amine

N-methyl-3-[3-(methylamino)-1-adamantyl]adamantan-1-amine, a complex organic compound, presents an interesting profile in terms of solubility. Its unique molecular structure, which combines both hydrophobic adamantane units and hydrophilic amine functional groups, contributes to its distinctive solubility behavior.

When considering solubility, it is important to note the following factors:

  • Polarity: The presence of the methylamino group enhances its polarity, suggesting that similar polar solvents (e.g., water, alcohols) may dissolve the compound to a certain extent.
  • Hydrophobic Regions: The adamantane structure is highly hydrophobic, which may lead to limited solubility in aqueous solutions but better solubility in organic solvents.
  • pH Dependence: The ionization of the amine groups can vary with pH, further influencing solubility in different environments.

Ultimately, while the compound may have some solubility in polar solvents due to its functional groups, it may exhibit significant challenges in achieving high solubility due to its bulky hydrophobic components. As a result, understanding the exact solubility requires careful examination of solvent interactions and environmental conditions.

Interesting facts

Interesting Facts about N-methyl-3-[3-(methylamino)-1-adamantyl]adamantan-1-amine

N-methyl-3-[3-(methylamino)-1-adamantyl]adamantan-1-amine is a fascinating chemical compound that falls into the category of adamantylamines, which have garnered significant interest in medicinal chemistry. Here are some key insights about this intriguing compound:

  • Structural Complexity: This compound showcases a unique and complex molecular structure that includes an adamantane core. The adamantane structure is known for its stability and has been likened to a "diamond-like" configuration, making it a prevalent motif in drug design.
  • Potential Biological Activity: The methylamino group in the molecule suggests that this compound may have interesting pharmacological properties. Compounds related to methylamino groups have been studied for their potential in neurological treatments and psychotropic effects.
  • Research Applications: Chemists often explore adamantylamines for their potential applications in treating various disorders, including ADHD and mental health conditions. Understanding the action mechanism of such compounds can lead to breakthroughs in drug development.
  • Chirality Considerations: The presence of asymmetric centers in the molecule opens up a discussion on stereochemistry. The three-dimensional orientation of the molecule can have significant effects on its biological interactions and properties.
  • Novel Derivatives: Researchers are continuously synthesizing new derivatives of adamantylamines to enhance efficacy and reduce side effects. Studying N-methyl-3-[3-(methylamino)-1-adamantyl]adamantan-1-amine can pave the way for discovering new therapeutic agents.

In summary, N-methyl-3-[3-(methylamino)-1-adamantyl]adamantan-1-amine is not just another chemical compound; it's a gateway to understanding complex biological mechanisms and developing innovative therapeutic solutions. As scientists delve deeper into its properties, they can unlock new frontiers in medicinal chemistry.

Synonyms
18220-69-4
N,N'-Dimethyl-1,1'-biadamantane-3,3'-diamine
N-methyl-3-[3-(methylamino)-1-adamantyl]adamantan-1-amine
BRN 2854498
1,1'-BIADAMANTANE-3,3'-DIAMINE, N,N'-DIMETHYL-
DTXSID60939544
3,3'-bis(N-methyl-amino)-[1,1'-biadamantane]
N~3~,N~3'~-Dimethyl[1,1'-bi(tricyclo[3.3.1.1~3,7~]decane)]-3,3'-diamine