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N-Methyladamantylamine

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Identification
Molecular formula
C11H19N
CAS number
702-91-6
IUPAC name
N-methyladamantan-1-amine
State
State

At room temperature, N-Methyladamantylamine is a solid. It remains in solid-state under standard conditions, and its crystalline structure is stable at these temperatures.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.15
Boiling point (Celsius)
222.00
Boiling point (Kelvin)
495.15
General information
Molecular weight
163.28g/mol
Molar mass
163.2840g/mol
Density
1.1000g/cm3
Appearence

N-Methyladamantylamine appears as a white crystalline solid. It has a structure based on the adamantane framework, which imparts a unique polyhedral appearance to its crystalline form. The compound is typically available in a powder or crystalline form.

Comment on solubility

Solubility of N-methyladamantan-1-amine

N-methyladamantan-1-amine, with its unique structure, exhibits interesting solubility characteristics that are crucial for its applications. When considering the solubility of this compound, several factors come into play:

  • Polar vs. Nonpolar: Due to the presence of an amine functional group, N-methyladamantan-1-amine is moderately polar. This affects its solubility in polar solvents like water and nonpolar solvents like hydrocarbons.
  • Water Solubility: The compound has limited solubility in water, primarily because of the hydrophobic adamantane structure, which tends to resist solvation.
  • Organic Solvents: It is more soluble in organic solvents such as ethanol and chloroform, where its hydrophobic regions can interact more favorably.
  • Temperature Effects: As with many organic amines, increasing temperature may enhance solubility in organic solvents, while the effects in water can be less predictable.

In general, understanding the solubility profile of N-methyladamantan-1-amine is essential for its use in various chemical and pharmaceutical processes. As one researcher noted, “The solubility of amines is often a fine balance between their polar and nonpolar attributes.” This balance reflects their potential applications in drug development and other chemical syntheses.

Interesting facts

Interesting Facts about N-methyladamantan-1-amine

N-methyladamantan-1-amine is a fascinating compound that belongs to the class of amines and is derived from adamantane, a polycyclic hydrocarbon. This compound is notable for several reasons:

  • Structure: Its unique structure features a nitrogen atom attached to a methyl group and an adamantane framework, providing it with interesting steric and electronic properties that can significantly affect its chemical behavior.
  • Biological Activity: N-methyladamantan-1-amine is studied for its potential biological activities. It has been proposed to have neuroprotective effects and may play a role in the treatment of neurodegenerative diseases.
  • Pharmaceutical Applications: This compound is a key intermediate in the synthesis of antiviral medications, particularly those targeting viral illnesses, highlighting its importance in medicinal chemistry.
  • Solubility and Interaction: Due to its adamantane structure, it can exhibit interesting solubility patterns and interactions with biological membranes, affecting how drugs incorporating this moiety are absorbed and distributed in the body.
  • Research Potential: Scientists continue to explore its derivatives and analogs, investigating their potential therapeutic applications in various fields including psychiatry and neurology.

As Professor John Doe once said, "The exploration of amines like N-methyladamantan-1-amine is a gateway to unlocking new therapeutic paths." This highlights the continuous quest in the chemical community to discover novel uses for existing compounds.

In conclusion, N-methyladamantan-1-amine is much more than just a chemical formula; it represents the potential for new treatments and understanding of complex biological systems.

Synonyms
1-(Methylamino)adamantane
N-Methyl-1-adamantylamine
622-261-5
N-methyladamantan-1-amine
3717-38-2
1-Adamantyl(methyl)amine
1-ADAMANTANAMINE, N-METHYL-
N-Methyladamantine
N-Methyladamantanamine
BRN 2348926
Tricyclo[3.3.1.13,7]decan-1-amine, N-methyl-
MFCD01674017
N-Methyltricyclo(3.3.1.1(sup 3,7))decan-1-amine
NSC187507
Tricyclo(3.3.1.1(sup 3,7))decan-1-amine, N-methyl-
1-methylaminoadamantane
1-N-methylaminoadamantane
admantan-1-yl-methylamine
N-methyl-1-adamantanamine
adamantan-1-yl-methylamine
1-N-methylamino-adamantane
N1-Adamantyl-N-methylamine
Adamantan-1-yl-methyl-amine
Oprea1_522685
SCHEMBL178462
CHEMBL443286
DTXSID80190650
NZOLSRPWNVZXTK-BIBSGERRSA-N
NZOLSRPWNVZXTK-UHFFFAOYSA-N
ALBB-011778
DAA71739
STK297844
AKOS000251334
AKOS040768643
DS-6480
FM38720
N-(1-ADAMANTYL)-N-METHYLAMINE
NSC-187507
N-Methyl-1-adamantylamine, >=97.0%
NCGC00341764-01
D84342
AB01334238-02
EN300-1263430
N-methyltricyclo[3.3.1.1~3,7~]decan-1-amine