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Memantine hydrochloride

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Identification
Molecular formula
C12H22ClN
CAS number
41100-52-1
IUPAC name
N-methyladamantan-1-amine;hydrochloride
State
State

Memantine hydrochloride is typically in a solid state at room temperature.

Melting point (Celsius)
292.00
Melting point (Kelvin)
565.15
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.15
General information
Molecular weight
215.77g/mol
Molar mass
215.7690g/mol
Density
1.1750g/cm3
Appearence

Memantine hydrochloride appears as a white to off-white crystalline powder. It is typically odorless.

Comment on solubility

Solubility of N-methyladamantan-1-amine;hydrochloride

N-methyladamantan-1-amine;hydrochloride, a quaternary ammonium compound, exhibits notable solubility characteristics that are of interest in both pharmaceutical and industrial applications.

When discussing the solubility of this compound, consider the following points:

  • Solubility in Water: N-methyladamantan-1-amine;hydrochloride is generally soluble in water due to the presence of the hydrochloride ion, which enhances its ability to ionize and interact with the polar water molecules.
  • Solubility in Organic Solvents: The solubility may vary in organic solvents. While it might be less soluble in non-polar solvents, moderate solubility could be expected in polar organic solvents such as ethanol and methanol.
  • Effect of pH: The solubility can also be influenced by the pH of the solution. As an amine, the protonation state of the compound will affect its solubility profile.

Overall, it is crucial to note that the solubility of N-methyladamantan-1-amine;hydrochloride facilitates its utilization in various applications, ranging from pharmacology to materials science. As always, when considering solubility, the temperature and specific solvent interactions should also be taken into account.

Interesting facts

Interesting Facts about N-methyladamantan-1-amine Hydrochloride

N-methyladamantan-1-amine hydrochloride, often referred to as a psychostimulant, holds significance in various fields including pharmacology and neurochemistry. Here are some captivating insights into this fascinating compound:

  • Structural Uniqueness: The compound is derived from adamantane, characterized by its cage-like structure. This unique configuration contributes to its interaction with biological systems.
  • Pharmacological Potential: As a methylated derivative of adamantan-1-amine, it shows potential in enhancing dopaminergic signaling, making it of interest for conditions related to attention and focus.
  • Research Applications: Scientists are investigating its properties for possible use in treating neurodegenerative diseases such as Alzheimer's, by exploring how it affects neurotransmitter systems.
  • Stability Considerations: Being a hydrochloride salt form, it typically provides improved stability and solubility compared to its free base counterparts, which is advantageous for formulation in pharmaceutical contexts.
  • Side Notes: While it is gaining attention for its potential therapeutic benefits, the compound's safety profile is still under investigation, making ongoing research crucial for its understanding.

In summary, N-methyladamantan-1-amine hydrochloride is more than just a chemical compound; it is a pathway to understanding complex interactions within neurochemistry and offers potential therapeutic avenues that are worth exploring. As Benjamin Franklin once said, “An investment in knowledge always pays the best interest,” and research on such compounds embodies the essence of that investment in scientific discovery.

Synonyms
N-methyladamantan-1-amine hydrochloride
982-768-5
3717-39-3
N-methyladamantan-1-amine;hydrochloride
1-(N-Methylamine)adamantanamine hydrochloride
NSC 187507
1-ADAMANTANAMINE, N-METHYL-, HYDROCHLORIDE
SCHEMBL3027024
MGWTWRYRZDCDBG-UHFFFAOYSA-N
AKOS024302080
adamantan-1-yl-methylamine hydrochloride
N-methyl-N-(1-adamantyl)amine hydrochloride